| Full name: reticulon 4 interacting protein 1 | Alias Symbol: NIMP | ||
| Type: protein-coding gene | Cytoband: 6q21 | ||
| Entrez ID: 84816 | HGNC ID: HGNC:18647 | Ensembl Gene: ENSG00000130347 | OMIM ID: 610502 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of RTN4IP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RTN4IP1 | 84816 | 224509_s_at | 0.1170 | 0.8478 | |
| GSE26886 | RTN4IP1 | 84816 | 224509_s_at | -0.0645 | 0.8226 | |
| GSE45670 | RTN4IP1 | 84816 | 224509_s_at | 0.6059 | 0.0001 | |
| GSE53622 | RTN4IP1 | 84816 | 41833 | 0.3436 | 0.0004 | |
| GSE53624 | RTN4IP1 | 84816 | 41833 | 0.5590 | 0.0000 | |
| GSE63941 | RTN4IP1 | 84816 | 1555679_a_at | 1.4530 | 0.0016 | |
| GSE77861 | RTN4IP1 | 84816 | 224509_s_at | 0.2531 | 0.2563 | |
| GSE97050 | RTN4IP1 | 84816 | A_23_P122775 | 0.1085 | 0.8415 | |
| SRP007169 | RTN4IP1 | 84816 | RNAseq | 0.4171 | 0.5046 | |
| SRP064894 | RTN4IP1 | 84816 | RNAseq | 0.4353 | 0.0495 | |
| SRP133303 | RTN4IP1 | 84816 | RNAseq | 0.3537 | 0.0121 | |
| SRP159526 | RTN4IP1 | 84816 | RNAseq | 0.4803 | 0.0151 | |
| SRP193095 | RTN4IP1 | 84816 | RNAseq | 0.0386 | 0.6910 | |
| SRP219564 | RTN4IP1 | 84816 | RNAseq | 0.1990 | 0.6012 | |
| TCGA | RTN4IP1 | 84816 | RNAseq | -0.1034 | 0.1524 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by RTN4IP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RTN4IP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RTN4IP1 | 84816 | 2 | 3 | 25 | |
| GSE20123 | RTN4IP1 | 84816 | 2 | 2 | 26 | |
| GSE43470 | RTN4IP1 | 84816 | 3 | 1 | 39 | |
| GSE46452 | RTN4IP1 | 84816 | 2 | 11 | 46 | |
| GSE47630 | RTN4IP1 | 84816 | 9 | 4 | 27 | |
| GSE54993 | RTN4IP1 | 84816 | 3 | 2 | 65 | |
| GSE54994 | RTN4IP1 | 84816 | 8 | 8 | 37 | |
| GSE60625 | RTN4IP1 | 84816 | 0 | 2 | 9 | |
| GSE74703 | RTN4IP1 | 84816 | 2 | 1 | 33 | |
| GSE74704 | RTN4IP1 | 84816 | 0 | 0 | 20 | |
| TCGA | RTN4IP1 | 84816 | 6 | 25 | 65 |
Total number of gains: 37; Total number of losses: 59; Total Number of normals: 392.
Somatic mutations of RTN4IP1:
Generating mutation plots.
Highly correlated genes for RTN4IP1:
Showing top 20/904 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RTN4IP1 | NSMCE4A | 0.790255 | 3 | 0 | 3 |
| RTN4IP1 | IER3IP1 | 0.778054 | 3 | 0 | 3 |
| RTN4IP1 | ERG | 0.774172 | 3 | 0 | 3 |
| RTN4IP1 | FRS2 | 0.767682 | 3 | 0 | 3 |
| RTN4IP1 | MREG | 0.766643 | 3 | 0 | 3 |
| RTN4IP1 | PPP1CC | 0.753314 | 4 | 0 | 3 |
| RTN4IP1 | ATXN10 | 0.740925 | 3 | 0 | 3 |
| RTN4IP1 | EPB41L5 | 0.740033 | 3 | 0 | 3 |
| RTN4IP1 | ATAD5 | 0.739154 | 3 | 0 | 3 |
| RTN4IP1 | LRIG3 | 0.736294 | 3 | 0 | 3 |
| RTN4IP1 | PSMD7 | 0.731772 | 5 | 0 | 4 |
| RTN4IP1 | ARHGEF5 | 0.729822 | 3 | 0 | 3 |
| RTN4IP1 | BZW1 | 0.72981 | 3 | 0 | 3 |
| RTN4IP1 | HMOX2 | 0.725318 | 3 | 0 | 3 |
| RTN4IP1 | COQ3 | 0.72426 | 8 | 0 | 8 |
| RTN4IP1 | LRRC58 | 0.722089 | 3 | 0 | 3 |
| RTN4IP1 | ADAT1 | 0.720281 | 5 | 0 | 4 |
| RTN4IP1 | HSBP1 | 0.716401 | 3 | 0 | 3 |
| RTN4IP1 | SCRN3 | 0.715882 | 3 | 0 | 3 |
| RTN4IP1 | TMEM107 | 0.71452 | 3 | 0 | 3 |
For details and further investigation, click here
