| Full name: maestro heat like repeat family member 1 | Alias Symbol: KIAA1833 | ||
| Type: protein-coding gene | Cytoband: 8q24.3 | ||
| Entrez ID: 727957 | HGNC ID: HGNC:26958 | Ensembl Gene: ENSG00000179832 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of MROH1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MROH1 | 727957 | 227778_at | 0.4303 | 0.6197 | |
| GSE26886 | MROH1 | 727957 | 227778_at | 0.4438 | 0.0176 | |
| GSE45670 | MROH1 | 727957 | 227778_at | 0.0016 | 0.9936 | |
| GSE53622 | MROH1 | 727957 | 83272 | 0.0265 | 0.7743 | |
| GSE53624 | MROH1 | 727957 | 83272 | -0.1391 | 0.0522 | |
| GSE63941 | MROH1 | 727957 | 227778_at | -0.3792 | 0.3929 | |
| GSE77861 | MROH1 | 727957 | 227778_at | -0.1135 | 0.5116 | |
| SRP007169 | MROH1 | 727957 | RNAseq | -0.9095 | 0.0426 | |
| SRP008496 | MROH1 | 727957 | RNAseq | -0.5277 | 0.0950 | |
| SRP064894 | MROH1 | 727957 | RNAseq | 0.6719 | 0.0044 | |
| SRP133303 | MROH1 | 727957 | RNAseq | 0.0917 | 0.5941 | |
| SRP159526 | MROH1 | 727957 | RNAseq | -0.2274 | 0.3649 | |
| SRP193095 | MROH1 | 727957 | RNAseq | 0.4743 | 0.0026 | |
| SRP219564 | MROH1 | 727957 | RNAseq | 0.5370 | 0.3496 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MROH1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of MROH1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MROH1 | 727957 | 17 | 1 | 12 | |
| GSE20123 | MROH1 | 727957 | 17 | 1 | 12 | |
| GSE43470 | MROH1 | 727957 | 16 | 2 | 25 | |
| GSE46452 | MROH1 | 727957 | 28 | 0 | 31 | |
| GSE47630 | MROH1 | 727957 | 23 | 1 | 16 | |
| GSE54993 | MROH1 | 727957 | 0 | 25 | 45 | |
| GSE54994 | MROH1 | 727957 | 39 | 1 | 13 | |
| GSE60625 | MROH1 | 727957 | 3 | 4 | 4 | |
| GSE74703 | MROH1 | 727957 | 14 | 1 | 21 | |
| GSE74704 | MROH1 | 727957 | 10 | 0 | 10 | |
| TCGA | MROH1 | 727957 | 63 | 2 | 31 |
Total number of gains: 230; Total number of losses: 38; Total Number of normals: 220.
Somatic mutations of MROH1:
Generating mutation plots.
Highly correlated genes for MROH1:
Showing top 20/40 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MROH1 | ZNF251 | 0.725137 | 3 | 0 | 3 |
| MROH1 | ZNF7 | 0.709887 | 3 | 0 | 3 |
| MROH1 | ZNF16 | 0.70693 | 3 | 0 | 3 |
| MROH1 | ZNF623 | 0.687593 | 3 | 0 | 3 |
| MROH1 | ZNF250 | 0.687224 | 3 | 0 | 3 |
| MROH1 | GAK | 0.672049 | 3 | 0 | 3 |
| MROH1 | TRIM8 | 0.641239 | 3 | 0 | 3 |
| MROH1 | PTK2 | 0.637154 | 3 | 0 | 3 |
| MROH1 | NOP14 | 0.633687 | 3 | 0 | 3 |
| MROH1 | FBXO2 | 0.621239 | 3 | 0 | 3 |
| MROH1 | LRRC14 | 0.615282 | 3 | 0 | 3 |
| MROH1 | PRKCZ | 0.613473 | 3 | 0 | 3 |
| MROH1 | DPP7 | 0.601312 | 3 | 0 | 3 |
| MROH1 | SCRIB | 0.59773 | 5 | 0 | 3 |
| MROH1 | PLXNA3 | 0.594369 | 4 | 0 | 3 |
| MROH1 | WBP2NL | 0.593968 | 4 | 0 | 3 |
| MROH1 | SHARPIN | 0.586491 | 6 | 0 | 4 |
| MROH1 | SLC52A2 | 0.581844 | 4 | 0 | 3 |
| MROH1 | KDM4B | 0.581232 | 3 | 0 | 3 |
| MROH1 | PPP1R16A | 0.58074 | 5 | 0 | 3 |
For details and further investigation, click here
