| Full name: thymopoietin | Alias Symbol: TP|LAP2|LEMD4 | ||
| Type: protein-coding gene | Cytoband: 12q23.1 | ||
| Entrez ID: 7112 | HGNC ID: HGNC:11875 | Ensembl Gene: ENSG00000120802 | OMIM ID: 188380 |
| Drug and gene relationship at DGIdb | |||
Expression of TMPO:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMPO | 7112 | 224944_at | 0.5643 | 0.1943 | |
| GSE20347 | TMPO | 7112 | 203432_at | 0.6659 | 0.0028 | |
| GSE23400 | TMPO | 7112 | 203432_at | 0.7359 | 0.0000 | |
| GSE26886 | TMPO | 7112 | 224944_at | 0.4500 | 0.0148 | |
| GSE29001 | TMPO | 7112 | 209753_s_at | 0.6335 | 0.0005 | |
| GSE38129 | TMPO | 7112 | 203432_at | 0.9781 | 0.0000 | |
| GSE45670 | TMPO | 7112 | 224944_at | 0.2398 | 0.2129 | |
| GSE53622 | TMPO | 7112 | 82898 | 0.3932 | 0.0001 | |
| GSE53624 | TMPO | 7112 | 82898 | 0.5217 | 0.0001 | |
| GSE63941 | TMPO | 7112 | 224944_at | 1.8514 | 0.0000 | |
| GSE77861 | TMPO | 7112 | 224944_at | 0.2815 | 0.3465 | |
| GSE97050 | TMPO | 7112 | A_23_P325040 | 0.5647 | 0.1782 | |
| SRP007169 | TMPO | 7112 | RNAseq | 0.5494 | 0.1153 | |
| SRP008496 | TMPO | 7112 | RNAseq | 0.4336 | 0.0685 | |
| SRP064894 | TMPO | 7112 | RNAseq | 0.2231 | 0.3603 | |
| SRP133303 | TMPO | 7112 | RNAseq | 0.7142 | 0.0054 | |
| SRP159526 | TMPO | 7112 | RNAseq | 0.6800 | 0.0346 | |
| SRP193095 | TMPO | 7112 | RNAseq | 0.2257 | 0.0377 | |
| SRP219564 | TMPO | 7112 | RNAseq | 0.1818 | 0.6832 | |
| TCGA | TMPO | 7112 | RNAseq | 0.2292 | 0.0002 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TMPO expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMPO:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMPO | 7112 | 2 | 3 | 25 | |
| GSE20123 | TMPO | 7112 | 2 | 3 | 25 | |
| GSE43470 | TMPO | 7112 | 2 | 0 | 41 | |
| GSE46452 | TMPO | 7112 | 9 | 1 | 49 | |
| GSE47630 | TMPO | 7112 | 9 | 2 | 29 | |
| GSE54993 | TMPO | 7112 | 0 | 5 | 65 | |
| GSE54994 | TMPO | 7112 | 4 | 2 | 47 | |
| GSE60625 | TMPO | 7112 | 0 | 0 | 11 | |
| GSE74703 | TMPO | 7112 | 2 | 0 | 34 | |
| GSE74704 | TMPO | 7112 | 1 | 2 | 17 | |
| TCGA | TMPO | 7112 | 17 | 9 | 70 |
Total number of gains: 48; Total number of losses: 27; Total Number of normals: 413.
Somatic mutations of TMPO:
Generating mutation plots.
Highly correlated genes for TMPO:
Showing top 20/1493 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMPO | KIAA1522 | 0.844641 | 3 | 0 | 3 |
| TMPO | SAMD1 | 0.760487 | 3 | 0 | 3 |
| TMPO | NRM | 0.753528 | 3 | 0 | 3 |
| TMPO | TMEM41A | 0.750963 | 3 | 0 | 3 |
| TMPO | AP1S3 | 0.749247 | 3 | 0 | 3 |
| TMPO | HIBADH | 0.745508 | 3 | 0 | 3 |
| TMPO | GIT1 | 0.743685 | 3 | 0 | 3 |
| TMPO | VANGL2 | 0.743059 | 3 | 0 | 3 |
| TMPO | MRPL38 | 0.739892 | 3 | 0 | 3 |
| TMPO | RPP38 | 0.7385 | 5 | 0 | 5 |
| TMPO | MRPL14 | 0.736342 | 4 | 0 | 4 |
| TMPO | C12orf60 | 0.736089 | 3 | 0 | 3 |
| TMPO | C1orf112 | 0.73262 | 10 | 0 | 9 |
| TMPO | DTX4 | 0.726389 | 3 | 0 | 3 |
| TMPO | ALG2 | 0.725482 | 3 | 0 | 3 |
| TMPO | CWF19L1 | 0.724436 | 5 | 0 | 4 |
| TMPO | WDR4 | 0.721344 | 3 | 0 | 3 |
| TMPO | MKI67 | 0.718987 | 9 | 0 | 8 |
| TMPO | DIP2B | 0.715583 | 3 | 0 | 3 |
| TMPO | CDCA7 | 0.713767 | 6 | 0 | 4 |
For details and further investigation, click here
