| Full name: solute carrier family 1 member 5 | Alias Symbol: AAAT|ASCT2 | ||
| Type: protein-coding gene | Cytoband: 19q13.32 | ||
| Entrez ID: 6510 | HGNC ID: HGNC:10943 | Ensembl Gene: ENSG00000105281 | OMIM ID: 109190 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC1A5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC1A5 | 6510 | 208916_at | 0.5989 | 0.0900 | |
| GSE20347 | SLC1A5 | 6510 | 208916_at | 0.6197 | 0.0001 | |
| GSE23400 | SLC1A5 | 6510 | 208916_at | 0.5503 | 0.0000 | |
| GSE26886 | SLC1A5 | 6510 | 208916_at | 0.4606 | 0.0575 | |
| GSE29001 | SLC1A5 | 6510 | 208916_at | 0.2515 | 0.1666 | |
| GSE38129 | SLC1A5 | 6510 | 208916_at | 0.7433 | 0.0000 | |
| GSE45670 | SLC1A5 | 6510 | 208916_at | 0.3755 | 0.0087 | |
| GSE63941 | SLC1A5 | 6510 | 208916_at | 1.4305 | 0.0294 | |
| GSE77861 | SLC1A5 | 6510 | 208916_at | 0.4968 | 0.0600 | |
| GSE97050 | SLC1A5 | 6510 | A_23_P55998 | 0.6203 | 0.1823 | |
| SRP007169 | SLC1A5 | 6510 | RNAseq | 1.1756 | 0.0088 | |
| SRP008496 | SLC1A5 | 6510 | RNAseq | 0.7975 | 0.0272 | |
| SRP064894 | SLC1A5 | 6510 | RNAseq | 0.8044 | 0.0058 | |
| SRP133303 | SLC1A5 | 6510 | RNAseq | 0.8742 | 0.0007 | |
| SRP159526 | SLC1A5 | 6510 | RNAseq | 0.7759 | 0.0311 | |
| SRP193095 | SLC1A5 | 6510 | RNAseq | 0.8716 | 0.0000 | |
| SRP219564 | SLC1A5 | 6510 | RNAseq | 0.7125 | 0.0388 | |
| TCGA | SLC1A5 | 6510 | RNAseq | 0.2002 | 0.0006 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by SLC1A5 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of SLC1A5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC1A5 | 6510 | 4 | 4 | 22 | |
| GSE20123 | SLC1A5 | 6510 | 4 | 3 | 23 | |
| GSE43470 | SLC1A5 | 6510 | 3 | 11 | 29 | |
| GSE46452 | SLC1A5 | 6510 | 45 | 1 | 13 | |
| GSE47630 | SLC1A5 | 6510 | 8 | 7 | 25 | |
| GSE54993 | SLC1A5 | 6510 | 17 | 4 | 49 | |
| GSE54994 | SLC1A5 | 6510 | 5 | 13 | 35 | |
| GSE60625 | SLC1A5 | 6510 | 9 | 0 | 2 | |
| GSE74703 | SLC1A5 | 6510 | 3 | 7 | 26 | |
| GSE74704 | SLC1A5 | 6510 | 4 | 1 | 15 | |
| TCGA | SLC1A5 | 6510 | 16 | 16 | 64 |
Total number of gains: 118; Total number of losses: 67; Total Number of normals: 303.
Somatic mutations of SLC1A5:
Generating mutation plots.
Highly correlated genes for SLC1A5:
Showing top 20/1426 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC1A5 | RNF4 | 0.832212 | 3 | 0 | 3 |
| SLC1A5 | NADSYN1 | 0.810303 | 3 | 0 | 3 |
| SLC1A5 | MRPL14 | 0.808801 | 3 | 0 | 3 |
| SLC1A5 | MFSD3 | 0.799157 | 3 | 0 | 3 |
| SLC1A5 | GEN1 | 0.793647 | 3 | 0 | 3 |
| SLC1A5 | C10orf55 | 0.790463 | 3 | 0 | 3 |
| SLC1A5 | SLC6A9 | 0.781799 | 3 | 0 | 3 |
| SLC1A5 | CHML | 0.748524 | 3 | 0 | 3 |
| SLC1A5 | CRTC2 | 0.734565 | 4 | 0 | 4 |
| SLC1A5 | TRIM59 | 0.731624 | 4 | 0 | 4 |
| SLC1A5 | STX5 | 0.729724 | 3 | 0 | 3 |
| SLC1A5 | ANLN | 0.729178 | 3 | 0 | 3 |
| SLC1A5 | GPR107 | 0.724397 | 3 | 0 | 3 |
| SLC1A5 | CDCA2 | 0.723414 | 4 | 0 | 4 |
| SLC1A5 | DPP9 | 0.72292 | 3 | 0 | 3 |
| SLC1A5 | ZBTB9 | 0.721426 | 3 | 0 | 3 |
| SLC1A5 | PSMG3 | 0.719114 | 4 | 0 | 4 |
| SLC1A5 | TIMELESS | 0.718847 | 7 | 0 | 7 |
| SLC1A5 | AP3D1 | 0.71753 | 4 | 0 | 3 |
| SLC1A5 | DUS3L | 0.717079 | 5 | 0 | 5 |
For details and further investigation, click here
