| Full name: mitochondrial ribosomal protein L16 | Alias Symbol: FLJ20484|PNAS-111 | ||
| Type: protein-coding gene | Cytoband: 11q12.1 | ||
| Entrez ID: 54948 | HGNC ID: HGNC:14476 | Ensembl Gene: ENSG00000166902 | OMIM ID: 611829 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MRPL16:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPL16 | 54948 | 217980_s_at | 0.1989 | 0.5501 | |
| GSE20347 | MRPL16 | 54948 | 217980_s_at | 0.3363 | 0.0181 | |
| GSE23400 | MRPL16 | 54948 | 217980_s_at | 0.2258 | 0.0000 | |
| GSE26886 | MRPL16 | 54948 | 217980_s_at | 0.4402 | 0.0332 | |
| GSE29001 | MRPL16 | 54948 | 217980_s_at | 0.0520 | 0.9020 | |
| GSE38129 | MRPL16 | 54948 | 217980_s_at | 0.0524 | 0.6928 | |
| GSE45670 | MRPL16 | 54948 | 217980_s_at | 0.0551 | 0.7370 | |
| GSE53622 | MRPL16 | 54948 | 16859 | 0.1070 | 0.1400 | |
| GSE53624 | MRPL16 | 54948 | 16859 | 0.4578 | 0.0000 | |
| GSE63941 | MRPL16 | 54948 | 217980_s_at | 0.2594 | 0.5554 | |
| GSE77861 | MRPL16 | 54948 | 217980_s_at | 0.1252 | 0.5895 | |
| GSE97050 | MRPL16 | 54948 | A_23_P47497 | -0.2438 | 0.3369 | |
| SRP007169 | MRPL16 | 54948 | RNAseq | 0.3255 | 0.4310 | |
| SRP008496 | MRPL16 | 54948 | RNAseq | -0.0854 | 0.7096 | |
| SRP064894 | MRPL16 | 54948 | RNAseq | 0.2115 | 0.1385 | |
| SRP133303 | MRPL16 | 54948 | RNAseq | 0.1896 | 0.2558 | |
| SRP159526 | MRPL16 | 54948 | RNAseq | 0.1879 | 0.2349 | |
| SRP193095 | MRPL16 | 54948 | RNAseq | 0.0238 | 0.8331 | |
| SRP219564 | MRPL16 | 54948 | RNAseq | 0.0745 | 0.8552 | |
| TCGA | MRPL16 | 54948 | RNAseq | -0.0504 | 0.3574 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MRPL16 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRPL16:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPL16 | 54948 | 1 | 5 | 24 | |
| GSE20123 | MRPL16 | 54948 | 1 | 5 | 24 | |
| GSE43470 | MRPL16 | 54948 | 2 | 5 | 36 | |
| GSE46452 | MRPL16 | 54948 | 9 | 4 | 46 | |
| GSE47630 | MRPL16 | 54948 | 3 | 8 | 29 | |
| GSE54993 | MRPL16 | 54948 | 3 | 0 | 67 | |
| GSE54994 | MRPL16 | 54948 | 5 | 6 | 42 | |
| GSE60625 | MRPL16 | 54948 | 0 | 3 | 8 | |
| GSE74703 | MRPL16 | 54948 | 2 | 3 | 31 | |
| GSE74704 | MRPL16 | 54948 | 1 | 4 | 15 | |
| TCGA | MRPL16 | 54948 | 14 | 10 | 72 |
Total number of gains: 41; Total number of losses: 53; Total Number of normals: 394.
Somatic mutations of MRPL16:
Generating mutation plots.
Highly correlated genes for MRPL16:
Showing top 20/598 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPL16 | PPTC7 | 0.784248 | 3 | 0 | 3 |
| MRPL16 | TIGD1 | 0.759733 | 3 | 0 | 3 |
| MRPL16 | RTF1 | 0.751868 | 3 | 0 | 3 |
| MRPL16 | HIRA | 0.746244 | 3 | 0 | 3 |
| MRPL16 | AQR | 0.712326 | 3 | 0 | 3 |
| MRPL16 | MRPL20 | 0.710228 | 3 | 0 | 3 |
| MRPL16 | MED26 | 0.707257 | 3 | 0 | 3 |
| MRPL16 | MRPS11 | 0.705092 | 3 | 0 | 3 |
| MRPL16 | NDRG3 | 0.701237 | 3 | 0 | 3 |
| MRPL16 | SPA17 | 0.696837 | 4 | 0 | 3 |
| MRPL16 | COMMD2 | 0.696224 | 3 | 0 | 3 |
| MRPL16 | GTPBP6 | 0.692644 | 3 | 0 | 3 |
| MRPL16 | WTAP | 0.691952 | 3 | 0 | 3 |
| MRPL16 | AURKAIP1 | 0.691411 | 4 | 0 | 3 |
| MRPL16 | SOCS4 | 0.687111 | 4 | 0 | 3 |
| MRPL16 | TMEM69 | 0.677557 | 3 | 0 | 3 |
| MRPL16 | MRPL40 | 0.672498 | 4 | 0 | 3 |
| MRPL16 | IDH3A | 0.671814 | 4 | 0 | 4 |
| MRPL16 | GOSR1 | 0.670897 | 3 | 0 | 3 |
| MRPL16 | UBE3A | 0.670854 | 4 | 0 | 4 |
For details and further investigation, click here
