| Full name: F-box protein 16 | Alias Symbol: FBX16 | ||
| Type: protein-coding gene | Cytoband: 8p21.1 | ||
| Entrez ID: 157574 | HGNC ID: HGNC:13618 | Ensembl Gene: ENSG00000214050 | OMIM ID: 608519 |
| Drug and gene relationship at DGIdb | |||
Expression of FBXO16:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FBXO16 | 157574 | 228427_at | 0.4689 | 0.4476 | |
| GSE26886 | FBXO16 | 157574 | 228427_at | 0.0094 | 0.9632 | |
| GSE45670 | FBXO16 | 157574 | 228427_at | 0.1933 | 0.3828 | |
| GSE53622 | FBXO16 | 157574 | 10777 | -0.1641 | 0.4914 | |
| GSE53624 | FBXO16 | 157574 | 10777 | 0.2861 | 0.0653 | |
| GSE63941 | FBXO16 | 157574 | 228427_at | 2.8514 | 0.0002 | |
| GSE77861 | FBXO16 | 157574 | 228427_at | -0.0612 | 0.6764 | |
| GSE97050 | FBXO16 | 157574 | A_23_P168847 | -0.0470 | 0.8987 | |
| SRP133303 | FBXO16 | 157574 | RNAseq | -0.3849 | 0.2458 | |
| SRP159526 | FBXO16 | 157574 | RNAseq | 1.2761 | 0.0062 | |
| TCGA | FBXO16 | 157574 | RNAseq | -0.3324 | 0.3871 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by FBXO16 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FBXO16:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FBXO16 | 157574 | 4 | 10 | 16 | |
| GSE20123 | FBXO16 | 157574 | 4 | 10 | 16 | |
| GSE43470 | FBXO16 | 157574 | 4 | 7 | 32 | |
| GSE46452 | FBXO16 | 157574 | 13 | 13 | 33 | |
| GSE47630 | FBXO16 | 157574 | 10 | 8 | 22 | |
| GSE54993 | FBXO16 | 157574 | 2 | 15 | 53 | |
| GSE54994 | FBXO16 | 157574 | 10 | 15 | 28 | |
| GSE60625 | FBXO16 | 157574 | 3 | 0 | 8 | |
| GSE74703 | FBXO16 | 157574 | 4 | 6 | 26 | |
| GSE74704 | FBXO16 | 157574 | 3 | 7 | 10 | |
| TCGA | FBXO16 | 157574 | 17 | 42 | 37 |
Total number of gains: 74; Total number of losses: 133; Total Number of normals: 281.
Somatic mutations of FBXO16:
Generating mutation plots.
Highly correlated genes for FBXO16:
Showing top 20/151 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FBXO16 | TCEANC2 | 0.853209 | 3 | 0 | 3 |
| FBXO16 | TRAP1 | 0.803966 | 3 | 0 | 3 |
| FBXO16 | MRPL38 | 0.799132 | 3 | 0 | 3 |
| FBXO16 | CNOT1 | 0.794797 | 3 | 0 | 3 |
| FBXO16 | FAM192A | 0.77473 | 3 | 0 | 3 |
| FBXO16 | RPA3 | 0.767661 | 3 | 0 | 3 |
| FBXO16 | LSM2 | 0.750888 | 3 | 0 | 3 |
| FBXO16 | RNPS1 | 0.749272 | 3 | 0 | 3 |
| FBXO16 | PPP5C | 0.745535 | 3 | 0 | 3 |
| FBXO16 | EFTUD2 | 0.743088 | 3 | 0 | 3 |
| FBXO16 | PPP1R35 | 0.742994 | 3 | 0 | 3 |
| FBXO16 | POLB | 0.729024 | 3 | 0 | 3 |
| FBXO16 | NDUFV1 | 0.727922 | 3 | 0 | 3 |
| FBXO16 | PTGES2 | 0.727666 | 3 | 0 | 3 |
| FBXO16 | MRPS34 | 0.725404 | 3 | 0 | 3 |
| FBXO16 | CSE1L | 0.721049 | 3 | 0 | 3 |
| FBXO16 | ACD | 0.720874 | 3 | 0 | 3 |
| FBXO16 | ZNF484 | 0.72054 | 3 | 0 | 3 |
| FBXO16 | EIF4A3 | 0.713309 | 3 | 0 | 3 |
| FBXO16 | E2F4 | 0.713045 | 3 | 0 | 3 |
For details and further investigation, click here
