| Full name: ring finger protein 126 | Alias Symbol: FLJ20552 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 55658 | HGNC ID: HGNC:21151 | Ensembl Gene: ENSG00000070423 | OMIM ID: 615177 |
| Drug and gene relationship at DGIdb | |||
Expression of RNF126:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNF126 | 55658 | 205748_s_at | 0.4696 | 0.4424 | |
| GSE20347 | RNF126 | 55658 | 205748_s_at | -0.0021 | 0.9918 | |
| GSE23400 | RNF126 | 55658 | 205748_s_at | 0.0638 | 0.3786 | |
| GSE26886 | RNF126 | 55658 | 223332_x_at | 0.3583 | 0.0163 | |
| GSE29001 | RNF126 | 55658 | 215031_x_at | -0.0772 | 0.7600 | |
| GSE38129 | RNF126 | 55658 | 205748_s_at | 0.2593 | 0.2463 | |
| GSE45670 | RNF126 | 55658 | 215031_x_at | 0.1369 | 0.2402 | |
| GSE63941 | RNF126 | 55658 | 205748_s_at | 3.0144 | 0.0000 | |
| GSE77861 | RNF126 | 55658 | 205748_s_at | 0.2773 | 0.0770 | |
| GSE97050 | RNF126 | 55658 | A_33_P3270102 | 0.2902 | 0.2257 | |
| SRP007169 | RNF126 | 55658 | RNAseq | -0.7680 | 0.0450 | |
| SRP008496 | RNF126 | 55658 | RNAseq | -1.2668 | 0.0000 | |
| SRP064894 | RNF126 | 55658 | RNAseq | 0.2224 | 0.3818 | |
| SRP133303 | RNF126 | 55658 | RNAseq | 0.1073 | 0.6144 | |
| SRP159526 | RNF126 | 55658 | RNAseq | -0.2476 | 0.1395 | |
| SRP193095 | RNF126 | 55658 | RNAseq | 0.0766 | 0.5666 | |
| SRP219564 | RNF126 | 55658 | RNAseq | -0.0312 | 0.9043 | |
| TCGA | RNF126 | 55658 | RNAseq | 0.1840 | 0.0007 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by RNF126 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of RNF126:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNF126 | 55658 | 4 | 6 | 20 | |
| GSE20123 | RNF126 | 55658 | 4 | 5 | 21 | |
| GSE43470 | RNF126 | 55658 | 1 | 10 | 32 | |
| GSE46452 | RNF126 | 55658 | 47 | 1 | 11 | |
| GSE47630 | RNF126 | 55658 | 5 | 7 | 28 | |
| GSE54993 | RNF126 | 55658 | 13 | 4 | 53 | |
| GSE54994 | RNF126 | 55658 | 8 | 15 | 30 | |
| GSE60625 | RNF126 | 55658 | 9 | 0 | 2 | |
| GSE74703 | RNF126 | 55658 | 1 | 7 | 28 | |
| GSE74704 | RNF126 | 55658 | 3 | 3 | 14 | |
| TCGA | RNF126 | 55658 | 8 | 25 | 63 |
Total number of gains: 103; Total number of losses: 83; Total Number of normals: 302.
Somatic mutations of RNF126:
Generating mutation plots.
Highly correlated genes for RNF126:
Showing top 20/590 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNF126 | MRPL38 | 0.792818 | 3 | 0 | 3 |
| RNF126 | PRPS2 | 0.756559 | 3 | 0 | 3 |
| RNF126 | WRAP73 | 0.753175 | 3 | 0 | 3 |
| RNF126 | KDF1 | 0.746997 | 3 | 0 | 3 |
| RNF126 | NOTCH1 | 0.724337 | 3 | 0 | 3 |
| RNF126 | TPD52 | 0.700579 | 3 | 0 | 3 |
| RNF126 | ASPSCR1 | 0.698104 | 4 | 0 | 4 |
| RNF126 | POLQ | 0.696925 | 3 | 0 | 3 |
| RNF126 | TOR3A | 0.694573 | 3 | 0 | 3 |
| RNF126 | CDK4 | 0.690347 | 5 | 0 | 5 |
| RNF126 | NOB1 | 0.689444 | 3 | 0 | 3 |
| RNF126 | MTFP1 | 0.679969 | 3 | 0 | 3 |
| RNF126 | SLC25A11 | 0.679139 | 3 | 0 | 3 |
| RNF126 | CHCHD5 | 0.676422 | 4 | 0 | 3 |
| RNF126 | MRPL4 | 0.671945 | 6 | 0 | 6 |
| RNF126 | TPM3 | 0.67097 | 3 | 0 | 3 |
| RNF126 | BCL11A | 0.670548 | 3 | 0 | 3 |
| RNF126 | PYGO2 | 0.670113 | 3 | 0 | 3 |
| RNF126 | EFNA3 | 0.66867 | 3 | 0 | 3 |
| RNF126 | COMMD2 | 0.666408 | 4 | 0 | 3 |
For details and further investigation, click here
