| Full name: NADH:ubiquinone oxidoreductase subunit B8 | Alias Symbol: ASHI|CI-ASHI | ||
| Type: protein-coding gene | Cytoband: 10q24.31 | ||
| Entrez ID: 4714 | HGNC ID: HGNC:7703 | Ensembl Gene: ENSG00000166136 | OMIM ID: 602140 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NDUFB8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NDUFB8 | 4714 | 201227_s_at | -0.3808 | 0.1410 | |
| GSE20347 | NDUFB8 | 4714 | 201227_s_at | -0.4821 | 0.0001 | |
| GSE23400 | NDUFB8 | 4714 | 201227_s_at | -0.3474 | 0.0000 | |
| GSE26886 | NDUFB8 | 4714 | 201227_s_at | -0.2368 | 0.0358 | |
| GSE29001 | NDUFB8 | 4714 | 201227_s_at | -0.3380 | 0.0353 | |
| GSE38129 | NDUFB8 | 4714 | 201227_s_at | -0.5160 | 0.0000 | |
| GSE45670 | NDUFB8 | 4714 | 201227_s_at | -0.2600 | 0.0016 | |
| GSE53622 | NDUFB8 | 4714 | 24406 | -0.4659 | 0.0000 | |
| GSE53624 | NDUFB8 | 4714 | 24406 | -0.1582 | 0.0002 | |
| GSE63941 | NDUFB8 | 4714 | 201227_s_at | -0.2718 | 0.3715 | |
| GSE77861 | NDUFB8 | 4714 | 201227_s_at | -0.3772 | 0.1799 | |
| GSE97050 | NDUFB8 | 4714 | A_33_P3384721 | -0.3558 | 0.3363 | |
| SRP007169 | NDUFB8 | 4714 | RNAseq | -0.7113 | 0.0670 | |
| SRP008496 | NDUFB8 | 4714 | RNAseq | -0.7774 | 0.0007 | |
| SRP064894 | NDUFB8 | 4714 | RNAseq | -0.2107 | 0.4091 | |
| SRP133303 | NDUFB8 | 4714 | RNAseq | -0.3516 | 0.0589 | |
| SRP159526 | NDUFB8 | 4714 | RNAseq | -0.2966 | 0.3074 | |
| SRP193095 | NDUFB8 | 4714 | RNAseq | -0.5306 | 0.0000 | |
| SRP219564 | NDUFB8 | 4714 | RNAseq | -0.7009 | 0.0719 | |
| TCGA | NDUFB8 | 4714 | RNAseq | -0.1805 | 0.0003 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NDUFB8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NDUFB8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NDUFB8 | 4714 | 1 | 8 | 21 | |
| GSE20123 | NDUFB8 | 4714 | 1 | 7 | 22 | |
| GSE43470 | NDUFB8 | 4714 | 0 | 8 | 35 | |
| GSE46452 | NDUFB8 | 4714 | 0 | 11 | 48 | |
| GSE47630 | NDUFB8 | 4714 | 2 | 14 | 24 | |
| GSE54993 | NDUFB8 | 4714 | 8 | 0 | 62 | |
| GSE54994 | NDUFB8 | 4714 | 1 | 12 | 40 | |
| GSE60625 | NDUFB8 | 4714 | 0 | 0 | 11 | |
| GSE74703 | NDUFB8 | 4714 | 0 | 5 | 31 | |
| GSE74704 | NDUFB8 | 4714 | 0 | 4 | 16 | |
| TCGA | NDUFB8 | 4714 | 5 | 28 | 63 |
Total number of gains: 18; Total number of losses: 97; Total Number of normals: 373.
Somatic mutations of NDUFB8:
Generating mutation plots.
Highly correlated genes for NDUFB8:
Showing top 20/745 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NDUFB8 | USP25 | 0.795456 | 3 | 0 | 3 |
| NDUFB8 | TMEM132C | 0.756187 | 3 | 0 | 3 |
| NDUFB8 | ARIH1 | 0.755414 | 3 | 0 | 3 |
| NDUFB8 | ESYT2 | 0.75095 | 3 | 0 | 3 |
| NDUFB8 | MRPL39 | 0.74714 | 3 | 0 | 3 |
| NDUFB8 | GTF3C6 | 0.745607 | 3 | 0 | 3 |
| NDUFB8 | PTGS1 | 0.739448 | 4 | 0 | 4 |
| NDUFB8 | UBE2G2 | 0.739314 | 3 | 0 | 3 |
| NDUFB8 | ZMYM5 | 0.733972 | 4 | 0 | 4 |
| NDUFB8 | NKIRAS1 | 0.732681 | 3 | 0 | 3 |
| NDUFB8 | TMEM126A | 0.732624 | 3 | 0 | 3 |
| NDUFB8 | PDCD4 | 0.728973 | 3 | 0 | 3 |
| NDUFB8 | GNG7 | 0.727722 | 3 | 0 | 3 |
| NDUFB8 | OR7A10 | 0.721956 | 4 | 0 | 4 |
| NDUFB8 | HINT3 | 0.721719 | 3 | 0 | 3 |
| NDUFB8 | DPH3 | 0.715965 | 3 | 0 | 3 |
| NDUFB8 | ACSS2 | 0.71173 | 3 | 0 | 3 |
| NDUFB8 | CLCC1 | 0.703161 | 5 | 0 | 5 |
| NDUFB8 | TADA2B | 0.698983 | 3 | 0 | 3 |
| NDUFB8 | RERG | 0.693135 | 3 | 0 | 3 |
For details and further investigation, click here
