| Full name: chromosome 3 open reading frame 80 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3q25.33 | ||
| Entrez ID: 401097 | HGNC ID: HGNC:40048 | Ensembl Gene: ENSG00000180044 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C3orf80:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C3orf80 | 401097 | 236738_at | -0.3724 | 0.7026 | |
| GSE26886 | C3orf80 | 401097 | 236738_at | -2.3944 | 0.0000 | |
| GSE45670 | C3orf80 | 401097 | 236738_at | -0.7012 | 0.1009 | |
| GSE53622 | C3orf80 | 401097 | 21761 | -0.5016 | 0.0086 | |
| GSE53624 | C3orf80 | 401097 | 21761 | -0.8888 | 0.0000 | |
| GSE63941 | C3orf80 | 401097 | 236738_at | -0.3205 | 0.7221 | |
| GSE77861 | C3orf80 | 401097 | 236738_at | -1.7260 | 0.0016 | |
| GSE97050 | C3orf80 | 401097 | A_33_P3257910 | 0.3068 | 0.5493 | |
| SRP007169 | C3orf80 | 401097 | RNAseq | -2.8503 | 0.0000 | |
| SRP064894 | C3orf80 | 401097 | RNAseq | -0.6901 | 0.0139 | |
| SRP133303 | C3orf80 | 401097 | RNAseq | -0.1610 | 0.6549 | |
| SRP159526 | C3orf80 | 401097 | RNAseq | -1.5693 | 0.0000 | |
| SRP219564 | C3orf80 | 401097 | RNAseq | -1.3512 | 0.1676 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by C3orf80 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of C3orf80:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C3orf80 | 401097 | 22 | 0 | 8 | |
| GSE20123 | C3orf80 | 401097 | 22 | 0 | 8 | |
| GSE43470 | C3orf80 | 401097 | 23 | 0 | 20 | |
| GSE46452 | C3orf80 | 401097 | 18 | 2 | 39 | |
| GSE47630 | C3orf80 | 401097 | 18 | 4 | 18 | |
| GSE54993 | C3orf80 | 401097 | 1 | 11 | 58 | |
| GSE54994 | C3orf80 | 401097 | 38 | 1 | 14 | |
| GSE60625 | C3orf80 | 401097 | 0 | 6 | 5 | |
| GSE74703 | C3orf80 | 401097 | 20 | 0 | 16 | |
| GSE74704 | C3orf80 | 401097 | 14 | 0 | 6 | |
| TCGA | C3orf80 | 401097 | 77 | 0 | 19 |
Total number of gains: 253; Total number of losses: 24; Total Number of normals: 211.
Somatic mutations of C3orf80:
Generating mutation plots.
Highly correlated genes for C3orf80:
Showing top 20/1001 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C3orf80 | VASH1 | 0.750475 | 3 | 0 | 3 |
| C3orf80 | SPNS2 | 0.74131 | 4 | 0 | 4 |
| C3orf80 | CTSS | 0.740682 | 3 | 0 | 3 |
| C3orf80 | MRPL39 | 0.738188 | 3 | 0 | 3 |
| C3orf80 | AVP | 0.735941 | 3 | 0 | 3 |
| C3orf80 | ZNRF1 | 0.727366 | 4 | 0 | 4 |
| C3orf80 | SIT1 | 0.720985 | 3 | 0 | 3 |
| C3orf80 | MMEL1 | 0.719478 | 4 | 0 | 4 |
| C3orf80 | RBM20 | 0.718441 | 4 | 0 | 4 |
| C3orf80 | PDLIM2 | 0.717643 | 5 | 0 | 4 |
| C3orf80 | ATP6V1C2 | 0.71621 | 5 | 0 | 5 |
| C3orf80 | HLA-DQB2 | 0.710815 | 4 | 0 | 3 |
| C3orf80 | CD59 | 0.710145 | 3 | 0 | 3 |
| C3orf80 | SLC25A51 | 0.70857 | 3 | 0 | 3 |
| C3orf80 | ACTR3 | 0.704141 | 3 | 0 | 3 |
| C3orf80 | XBP1 | 0.701827 | 3 | 0 | 3 |
| C3orf80 | PRSS2 | 0.701589 | 4 | 0 | 4 |
| C3orf80 | SFTA2 | 0.701086 | 4 | 0 | 4 |
| C3orf80 | ZNF416 | 0.698969 | 4 | 0 | 4 |
| C3orf80 | ZNF844 | 0.698835 | 4 | 0 | 4 |
For details and further investigation, click here
