ICE2

 

Full name: interactor of little elongation complex ELL subunit 2 Alias Symbol: FLJ11896|BRCC1
Type: protein-coding gene Cytoband: 15q22.2
Entrez ID: 79664 HGNC ID: HGNC:29885 Ensembl Gene: ENSG00000128915 OMIM ID: 610835
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of ICE2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ICE2 79664 218713_at -0.2560 0.5531
GSE20347 ICE2 79664 218713_at 0.2583 0.1105
GSE23400 ICE2 79664 218713_at 0.3374 0.0000
GSE26886 ICE2 79664 218713_at 0.6005 0.0045
GSE29001 ICE2 79664 218713_at 0.3423 0.2254
GSE38129 ICE2 79664 218713_at 0.2198 0.0599
GSE45670 ICE2 79664 218713_at 0.1485 0.2721
GSE53622 ICE2 79664 543 -0.7318 0.0000
GSE53624 ICE2 79664 543 -0.4250 0.0000
GSE63941 ICE2 79664 218713_at 0.5512 0.1963
GSE77861 ICE2 79664 218713_at 0.3069 0.1963
SRP007169 ICE2 79664 RNAseq 0.2588 0.5916
SRP008496 ICE2 79664 RNAseq 0.2735 0.3259
SRP064894 ICE2 79664 RNAseq -0.1189 0.4647
SRP133303 ICE2 79664 RNAseq 0.2548 0.0797
SRP159526 ICE2 79664 RNAseq -0.1208 0.6830
SRP193095 ICE2 79664 RNAseq 0.0071 0.9282
SRP219564 ICE2 79664 RNAseq 0.0125 0.9633

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by ICE2 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  

Copy number change of ICE2:

 

No record found for this gene.

 

Somatic mutations of ICE2:

 

Generating mutation plots.

 

Highly correlated genes for ICE2:

 

Showing top 20/175 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ICE2MSI20.767875303
ICE2ASXL20.669784404
ICE2HERC20.660929404
ICE2CASC40.643033403
ICE2ARNT20.630466303
ICE2KCNE30.627809303
ICE2RCN20.622007805
ICE2ETAA10.620448605
ICE2BNIP20.618645806
ICE2PHIP0.615705504
ICE2ZNF7030.614461303
ICE2EID10.614419705
ICE2ZNF2750.613105403
ICE2SMARCA50.607873604
ICE2ARPP190.600437705
ICE2SACS0.600353504
ICE2KRR10.599786504
ICE2DUT0.598199807
ICE2LRIG30.595947303
ICE2GDPD10.595655504

For details and further investigation, click here