| Full name: metastasis associated 1 family member 2 | Alias Symbol: MTA1-L1 | ||
| Type: protein-coding gene | Cytoband: 11q12.3 | ||
| Entrez ID: 9219 | HGNC ID: HGNC:7411 | Ensembl Gene: ENSG00000149480 | OMIM ID: 603947 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MTA2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MTA2 | 9219 | 203444_s_at | -0.0772 | 0.8706 | |
| GSE20347 | MTA2 | 9219 | 203444_s_at | -0.5050 | 0.0000 | |
| GSE23400 | MTA2 | 9219 | 203444_s_at | -0.2361 | 0.0000 | |
| GSE26886 | MTA2 | 9219 | 203444_s_at | -0.1191 | 0.5638 | |
| GSE29001 | MTA2 | 9219 | 203444_s_at | -0.6400 | 0.0003 | |
| GSE38129 | MTA2 | 9219 | 203444_s_at | -0.3101 | 0.0818 | |
| GSE45670 | MTA2 | 9219 | 203444_s_at | -0.2738 | 0.0746 | |
| GSE53622 | MTA2 | 9219 | 4023 | -0.2049 | 0.0098 | |
| GSE53624 | MTA2 | 9219 | 4023 | -0.0772 | 0.1946 | |
| GSE63941 | MTA2 | 9219 | 203444_s_at | 0.7966 | 0.0183 | |
| GSE77861 | MTA2 | 9219 | 203444_s_at | -0.3907 | 0.0367 | |
| GSE97050 | MTA2 | 9219 | A_23_P203420 | 0.0056 | 0.9891 | |
| SRP007169 | MTA2 | 9219 | RNAseq | -0.5434 | 0.0648 | |
| SRP008496 | MTA2 | 9219 | RNAseq | -0.5353 | 0.0018 | |
| SRP064894 | MTA2 | 9219 | RNAseq | -0.2640 | 0.0454 | |
| SRP133303 | MTA2 | 9219 | RNAseq | -0.2812 | 0.1608 | |
| SRP159526 | MTA2 | 9219 | RNAseq | -0.1856 | 0.3950 | |
| SRP193095 | MTA2 | 9219 | RNAseq | -0.1371 | 0.2921 | |
| SRP219564 | MTA2 | 9219 | RNAseq | -0.2061 | 0.5619 | |
| TCGA | MTA2 | 9219 | RNAseq | 0.1241 | 0.0061 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MTA2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MTA2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MTA2 | 9219 | 6 | 5 | 19 | |
| GSE20123 | MTA2 | 9219 | 6 | 5 | 19 | |
| GSE43470 | MTA2 | 9219 | 1 | 6 | 36 | |
| GSE46452 | MTA2 | 9219 | 8 | 4 | 47 | |
| GSE47630 | MTA2 | 9219 | 3 | 7 | 30 | |
| GSE54993 | MTA2 | 9219 | 3 | 0 | 67 | |
| GSE54994 | MTA2 | 9219 | 4 | 5 | 44 | |
| GSE60625 | MTA2 | 9219 | 0 | 3 | 8 | |
| GSE74703 | MTA2 | 9219 | 1 | 3 | 32 | |
| GSE74704 | MTA2 | 9219 | 4 | 3 | 13 | |
| TCGA | MTA2 | 9219 | 14 | 11 | 71 |
Total number of gains: 50; Total number of losses: 52; Total Number of normals: 386.
Somatic mutations of MTA2:
Generating mutation plots.
Highly correlated genes for MTA2:
Showing top 20/931 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MTA2 | LRRC28 | 0.728065 | 3 | 0 | 3 |
| MTA2 | OTUB1 | 0.727442 | 3 | 0 | 3 |
| MTA2 | RBAK | 0.712844 | 3 | 0 | 3 |
| MTA2 | SUSD1 | 0.708732 | 3 | 0 | 3 |
| MTA2 | PRELID1 | 0.702348 | 4 | 0 | 4 |
| MTA2 | DLG2 | 0.699638 | 6 | 0 | 5 |
| MTA2 | ESYT2 | 0.697866 | 3 | 0 | 3 |
| MTA2 | PLEKHA2 | 0.697747 | 3 | 0 | 3 |
| MTA2 | TOLLIP | 0.69222 | 8 | 0 | 7 |
| MTA2 | TMEM62 | 0.690684 | 3 | 0 | 3 |
| MTA2 | ZNRF1 | 0.690669 | 3 | 0 | 3 |
| MTA2 | SLC25A23 | 0.689355 | 5 | 0 | 5 |
| MTA2 | FAM204A | 0.689125 | 3 | 0 | 3 |
| MTA2 | CPTP | 0.688897 | 6 | 0 | 6 |
| MTA2 | CLEC16A | 0.688675 | 4 | 0 | 4 |
| MTA2 | SNRK | 0.686918 | 4 | 0 | 4 |
| MTA2 | PRRG2 | 0.686623 | 7 | 0 | 7 |
| MTA2 | MRPL49 | 0.680427 | 3 | 0 | 3 |
| MTA2 | SMPD2 | 0.680094 | 8 | 0 | 7 |
| MTA2 | PUSL1 | 0.680021 | 5 | 0 | 4 |
For details and further investigation, click here
