| Full name: proline rich and Gla domain 2 | Alias Symbol: PRGP2 | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 5639 | HGNC ID: HGNC:9470 | Ensembl Gene: ENSG00000126460 | OMIM ID: 604429 |
| Drug and gene relationship at DGIdb | |||
Expression of PRRG2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRRG2 | 5639 | 205617_at | -0.1769 | 0.7324 | |
| GSE20347 | PRRG2 | 5639 | 205617_at | -0.4500 | 0.0000 | |
| GSE23400 | PRRG2 | 5639 | 205617_at | -0.2985 | 0.0000 | |
| GSE26886 | PRRG2 | 5639 | 205617_at | -0.0385 | 0.8344 | |
| GSE29001 | PRRG2 | 5639 | 205617_at | -0.6246 | 0.0002 | |
| GSE38129 | PRRG2 | 5639 | 205617_at | -0.3329 | 0.0075 | |
| GSE45670 | PRRG2 | 5639 | 205617_at | -0.0027 | 0.9860 | |
| GSE53622 | PRRG2 | 5639 | 92903 | -0.7032 | 0.0000 | |
| GSE53624 | PRRG2 | 5639 | 92903 | -0.5784 | 0.0000 | |
| GSE63941 | PRRG2 | 5639 | 205617_at | 1.0857 | 0.0014 | |
| GSE77861 | PRRG2 | 5639 | 205617_at | -0.1850 | 0.1869 | |
| GSE97050 | PRRG2 | 5639 | A_23_P67355 | -0.2948 | 0.3692 | |
| SRP007169 | PRRG2 | 5639 | RNAseq | -2.0947 | 0.0000 | |
| SRP008496 | PRRG2 | 5639 | RNAseq | -2.2572 | 0.0000 | |
| SRP064894 | PRRG2 | 5639 | RNAseq | -0.8632 | 0.0122 | |
| SRP133303 | PRRG2 | 5639 | RNAseq | -0.8509 | 0.0121 | |
| SRP159526 | PRRG2 | 5639 | RNAseq | -0.7995 | 0.0000 | |
| SRP193095 | PRRG2 | 5639 | RNAseq | -0.8926 | 0.0000 | |
| SRP219564 | PRRG2 | 5639 | RNAseq | -1.6223 | 0.0375 | |
| TCGA | PRRG2 | 5639 | RNAseq | -0.1289 | 0.4202 |
Upregulated datasets: 1; Downregulated datasets: 3.
Survival by PRRG2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRRG2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRRG2 | 5639 | 4 | 4 | 22 | |
| GSE20123 | PRRG2 | 5639 | 4 | 3 | 23 | |
| GSE43470 | PRRG2 | 5639 | 4 | 11 | 28 | |
| GSE46452 | PRRG2 | 5639 | 45 | 1 | 13 | |
| GSE47630 | PRRG2 | 5639 | 10 | 6 | 24 | |
| GSE54993 | PRRG2 | 5639 | 17 | 4 | 49 | |
| GSE54994 | PRRG2 | 5639 | 4 | 14 | 35 | |
| GSE60625 | PRRG2 | 5639 | 9 | 0 | 2 | |
| GSE74703 | PRRG2 | 5639 | 4 | 7 | 25 | |
| GSE74704 | PRRG2 | 5639 | 4 | 1 | 15 | |
| TCGA | PRRG2 | 5639 | 14 | 19 | 63 |
Total number of gains: 119; Total number of losses: 70; Total Number of normals: 299.
Somatic mutations of PRRG2:
Generating mutation plots.
Highly correlated genes for PRRG2:
Showing top 20/1034 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRRG2 | RAB25 | 0.722041 | 10 | 0 | 9 |
| PRRG2 | TOLLIP | 0.720322 | 7 | 0 | 6 |
| PRRG2 | TICAM1 | 0.694868 | 5 | 0 | 4 |
| PRRG2 | CPTP | 0.691737 | 8 | 0 | 6 |
| PRRG2 | TM7SF2 | 0.690906 | 10 | 0 | 9 |
| PRRG2 | MTA2 | 0.686623 | 7 | 0 | 7 |
| PRRG2 | SYTL1 | 0.684169 | 6 | 0 | 6 |
| PRRG2 | RABGGTA | 0.681595 | 9 | 0 | 8 |
| PRRG2 | EPS8L1 | 0.678916 | 11 | 0 | 10 |
| PRRG2 | CDS1 | 0.677996 | 9 | 0 | 7 |
| PRRG2 | EVPL | 0.676016 | 12 | 0 | 11 |
| PRRG2 | PRSS3 | 0.672931 | 8 | 0 | 8 |
| PRRG2 | CARD14 | 0.672725 | 9 | 0 | 8 |
| PRRG2 | EPS8L2 | 0.672047 | 10 | 0 | 7 |
| PRRG2 | TOM1 | 0.671961 | 9 | 0 | 8 |
| PRRG2 | RIPK4 | 0.670586 | 9 | 0 | 8 |
| PRRG2 | ITGB7 | 0.669582 | 6 | 0 | 6 |
| PRRG2 | TECR | 0.669473 | 11 | 0 | 10 |
| PRRG2 | RARG | 0.669338 | 11 | 0 | 9 |
| PRRG2 | EBPL | 0.667093 | 3 | 0 | 3 |
For details and further investigation, click here
