MTFR1

 

Full name: mitochondrial fission regulator 1 Alias Symbol: CHPPR|KIAA0009|FAM54A2
Type: protein-coding gene Cytoband: 8q13.1
Entrez ID: 9650 HGNC ID: HGNC:29510 Ensembl Gene: ENSG00000066855 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of MTFR1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 MTFR1 9650 203208_s_at 0.9888 0.0642
GSE20347 MTFR1 9650 203208_s_at 0.6710 0.0001
GSE23400 MTFR1 9650 203208_s_at 0.4994 0.0000
GSE26886 MTFR1 9650 203208_s_at 0.3423 0.0741
GSE29001 MTFR1 9650 203208_s_at 0.5344 0.0983
GSE38129 MTFR1 9650 203208_s_at 0.6920 0.0000
GSE45670 MTFR1 9650 203208_s_at 0.5549 0.0011
GSE53622 MTFR1 9650 50862 0.5888 0.0000
GSE53624 MTFR1 9650 50862 0.6130 0.0000
GSE63941 MTFR1 9650 203208_s_at 0.2671 0.6247
GSE77861 MTFR1 9650 203208_s_at 0.2405 0.3029
GSE97050 MTFR1 9650 A_24_P346587 0.3693 0.1927
SRP007169 MTFR1 9650 RNAseq -0.0929 0.8113
SRP008496 MTFR1 9650 RNAseq 0.1199 0.6870
SRP064894 MTFR1 9650 RNAseq 0.5812 0.0166
SRP133303 MTFR1 9650 RNAseq 0.8131 0.0000
SRP159526 MTFR1 9650 RNAseq 0.3938 0.2003
SRP193095 MTFR1 9650 RNAseq 0.2284 0.0583
SRP219564 MTFR1 9650 RNAseq 0.5423 0.2080
TCGA MTFR1 9650 RNAseq 0.0431 0.4864

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by MTFR1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of MTFR1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 MTFR1 9650 13 1 16
GSE20123 MTFR1 9650 13 1 16
GSE43470 MTFR1 9650 15 3 25
GSE46452 MTFR1 9650 21 1 37
GSE47630 MTFR1 9650 23 1 16
GSE54993 MTFR1 9650 1 18 51
GSE54994 MTFR1 9650 30 0 23
GSE60625 MTFR1 9650 0 4 7
GSE74703 MTFR1 9650 13 2 21
GSE74704 MTFR1 9650 9 0 11
TCGA MTFR1 9650 48 5 43

Total number of gains: 186; Total number of losses: 36; Total Number of normals: 266.  

 

Somatic mutations of MTFR1:

 

Generating mutation plots.

 

Highly correlated genes for MTFR1:

 

Showing top 20/1369 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
MTFR1TP53RK0.825911303
MTFR1TYW50.747609303
MTFR1ARHGAP390.72887303
MTFR1LRRC580.726373404
MTFR1COPS50.72560112012
MTFR1SLC7A6OS0.723583505
MTFR1ALG10.718458303
MTFR1POLR2K0.71456908
MTFR1PDRG10.714397404
MTFR1B3GALT60.703004403
MTFR1MTERF30.700233908
MTFR1SIX40.696015504
MTFR1GZF10.691719303
MTFR1ARMC10.69083713010
MTFR1UBTD20.68947404
MTFR1DPY19L40.68936412011
MTFR1TMEM700.687482808
MTFR1MAP4K40.686224303
MTFR1CENPBD10.685611403
MTFR1PPP1R9B0.683323303

For details and further investigation, click here