| Full name: receptor accessory protein 6 | Alias Symbol: DP1L1|FLJ25383|Yip2f | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 92840 | HGNC ID: HGNC:30078 | Ensembl Gene: ENSG00000115255 | OMIM ID: 609346 |
| Drug and gene relationship at DGIdb | |||
Expression of REEP6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | REEP6 | 92840 | 226597_at | -0.3583 | 0.6545 | |
| GSE26886 | REEP6 | 92840 | 226597_at | -0.7782 | 0.0046 | |
| GSE45670 | REEP6 | 92840 | 226597_at | -0.1805 | 0.4598 | |
| GSE53622 | REEP6 | 92840 | 18207 | -0.1330 | 0.0648 | |
| GSE53624 | REEP6 | 92840 | 30133 | -1.1223 | 0.0000 | |
| GSE63941 | REEP6 | 92840 | 226597_at | 1.5117 | 0.0306 | |
| GSE77861 | REEP6 | 92840 | 226597_at | -0.5586 | 0.1499 | |
| GSE97050 | REEP6 | 92840 | A_33_P3369834 | -0.1289 | 0.7141 | |
| SRP007169 | REEP6 | 92840 | RNAseq | -3.9327 | 0.0000 | |
| SRP064894 | REEP6 | 92840 | RNAseq | -0.3266 | 0.4065 | |
| SRP133303 | REEP6 | 92840 | RNAseq | -1.5120 | 0.0000 | |
| SRP159526 | REEP6 | 92840 | RNAseq | -1.4154 | 0.0001 | |
| SRP193095 | REEP6 | 92840 | RNAseq | -1.5656 | 0.0000 | |
| SRP219564 | REEP6 | 92840 | RNAseq | -0.0091 | 0.9911 | |
| TCGA | REEP6 | 92840 | RNAseq | 0.2362 | 0.1630 |
Upregulated datasets: 1; Downregulated datasets: 5.
Survival by REEP6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of REEP6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | REEP6 | 92840 | 4 | 6 | 20 | |
| GSE20123 | REEP6 | 92840 | 4 | 5 | 21 | |
| GSE43470 | REEP6 | 92840 | 1 | 11 | 31 | |
| GSE46452 | REEP6 | 92840 | 47 | 1 | 11 | |
| GSE47630 | REEP6 | 92840 | 5 | 7 | 28 | |
| GSE54993 | REEP6 | 92840 | 16 | 3 | 51 | |
| GSE54994 | REEP6 | 92840 | 8 | 15 | 30 | |
| GSE60625 | REEP6 | 92840 | 9 | 0 | 2 | |
| GSE74703 | REEP6 | 92840 | 1 | 8 | 27 | |
| GSE74704 | REEP6 | 92840 | 3 | 3 | 14 | |
| TCGA | REEP6 | 92840 | 6 | 25 | 65 |
Total number of gains: 104; Total number of losses: 84; Total Number of normals: 300.
Somatic mutations of REEP6:
Generating mutation plots.
Highly correlated genes for REEP6:
Showing top 20/415 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| REEP6 | RNPEPL1 | 0.700536 | 4 | 0 | 4 |
| REEP6 | POLR2L | 0.696056 | 3 | 0 | 3 |
| REEP6 | MTMR14 | 0.670824 | 3 | 0 | 3 |
| REEP6 | MYD88 | 0.664041 | 5 | 0 | 5 |
| REEP6 | POLR2I | 0.658794 | 3 | 0 | 3 |
| REEP6 | LMNTD2 | 0.652888 | 4 | 0 | 3 |
| REEP6 | RAB4B | 0.648615 | 4 | 0 | 4 |
| REEP6 | FLT4 | 0.6473 | 3 | 0 | 3 |
| REEP6 | BCL10 | 0.634709 | 3 | 0 | 3 |
| REEP6 | AP2M1 | 0.634411 | 3 | 0 | 3 |
| REEP6 | SH3BGRL3 | 0.629873 | 4 | 0 | 3 |
| REEP6 | ENSA | 0.629707 | 6 | 0 | 6 |
| REEP6 | CRABP2 | 0.628904 | 4 | 0 | 3 |
| REEP6 | FBXL16 | 0.628408 | 6 | 0 | 6 |
| REEP6 | MYL12A | 0.626208 | 3 | 0 | 3 |
| REEP6 | ACY1 | 0.624898 | 3 | 0 | 3 |
| REEP6 | LLGL2 | 0.624832 | 5 | 0 | 5 |
| REEP6 | MINK1 | 0.622162 | 5 | 0 | 5 |
| REEP6 | MOSPD3 | 0.62116 | 5 | 0 | 5 |
| REEP6 | SH3GL1 | 0.616986 | 6 | 0 | 6 |
For details and further investigation, click here
