| Full name: coiled-coil domain containing 68 | Alias Symbol: SE57-1 | ||
| Type: protein-coding gene | Cytoband: 18q21.2 | ||
| Entrez ID: 80323 | HGNC ID: HGNC:24350 | Ensembl Gene: ENSG00000166510 | OMIM ID: 616909 |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC68:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC68 | 80323 | 220180_at | -0.0567 | 0.9448 | |
| GSE20347 | CCDC68 | 80323 | 220180_at | -0.0888 | 0.4495 | |
| GSE23400 | CCDC68 | 80323 | 220180_at | -0.0028 | 0.9595 | |
| GSE26886 | CCDC68 | 80323 | 220180_at | -0.1110 | 0.7158 | |
| GSE29001 | CCDC68 | 80323 | 220180_at | 0.1024 | 0.7697 | |
| GSE38129 | CCDC68 | 80323 | 220180_at | -0.2781 | 0.0367 | |
| GSE45670 | CCDC68 | 80323 | 220180_at | 0.0893 | 0.8802 | |
| GSE53622 | CCDC68 | 80323 | 133366 | -0.8169 | 0.0014 | |
| GSE53624 | CCDC68 | 80323 | 133366 | -0.6428 | 0.0101 | |
| GSE63941 | CCDC68 | 80323 | 220180_at | -5.0422 | 0.0000 | |
| GSE77861 | CCDC68 | 80323 | 220180_at | -0.0480 | 0.6607 | |
| SRP064894 | CCDC68 | 80323 | RNAseq | -0.1844 | 0.6451 | |
| SRP133303 | CCDC68 | 80323 | RNAseq | -0.0890 | 0.7727 | |
| SRP159526 | CCDC68 | 80323 | RNAseq | -1.0271 | 0.0078 | |
| SRP193095 | CCDC68 | 80323 | RNAseq | -1.0346 | 0.0430 | |
| SRP219564 | CCDC68 | 80323 | RNAseq | -1.0243 | 0.0635 | |
| TCGA | CCDC68 | 80323 | RNAseq | -1.0445 | 0.0030 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by CCDC68 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC68:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC68 | 80323 | 2 | 9 | 19 | |
| GSE20123 | CCDC68 | 80323 | 2 | 9 | 19 | |
| GSE43470 | CCDC68 | 80323 | 0 | 5 | 38 | |
| GSE46452 | CCDC68 | 80323 | 1 | 26 | 32 | |
| GSE47630 | CCDC68 | 80323 | 5 | 20 | 15 | |
| GSE54993 | CCDC68 | 80323 | 10 | 0 | 60 | |
| GSE54994 | CCDC68 | 80323 | 1 | 17 | 35 | |
| GSE60625 | CCDC68 | 80323 | 0 | 4 | 7 | |
| GSE74703 | CCDC68 | 80323 | 0 | 5 | 31 | |
| GSE74704 | CCDC68 | 80323 | 2 | 6 | 12 | |
| TCGA | CCDC68 | 80323 | 10 | 43 | 43 |
Total number of gains: 33; Total number of losses: 144; Total Number of normals: 311.
Somatic mutations of CCDC68:
Generating mutation plots.
Highly correlated genes for CCDC68:
Showing top 20/25 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC68 | MTMR6 | 0.719191 | 3 | 0 | 3 |
| CCDC68 | CDIPT | 0.666762 | 3 | 0 | 3 |
| CCDC68 | SLC30A5 | 0.625476 | 4 | 0 | 3 |
| CCDC68 | ACKR4 | 0.623158 | 4 | 0 | 3 |
| CCDC68 | PPIP5K2 | 0.615553 | 3 | 0 | 3 |
| CCDC68 | RTN1 | 0.607536 | 3 | 0 | 3 |
| CCDC68 | NDEL1 | 0.597956 | 3 | 0 | 3 |
| CCDC68 | JAM2 | 0.573412 | 4 | 0 | 3 |
| CCDC68 | LYSMD3 | 0.563649 | 5 | 0 | 3 |
| CCDC68 | ISOC1 | 0.558408 | 3 | 0 | 3 |
| CCDC68 | PCYOX1 | 0.558085 | 4 | 0 | 3 |
| CCDC68 | TESC | 0.552291 | 3 | 0 | 3 |
| CCDC68 | SUCLA2 | 0.544978 | 5 | 0 | 3 |
| CCDC68 | BBS12 | 0.54257 | 3 | 0 | 3 |
| CCDC68 | ATP10D | 0.535779 | 5 | 0 | 3 |
| CCDC68 | HOXB5 | 0.533716 | 3 | 0 | 3 |
| CCDC68 | SNTB2 | 0.525278 | 4 | 0 | 3 |
| CCDC68 | FUT4 | 0.52446 | 5 | 0 | 3 |
| CCDC68 | CRY1 | 0.522625 | 4 | 0 | 3 |
| CCDC68 | MILR1 | 0.519226 | 5 | 0 | 3 |
For details and further investigation, click here
