| Full name: myosin heavy chain 15 | Alias Symbol: KIAA1000 | ||
| Type: protein-coding gene | Cytoband: 3q13.13 | ||
| Entrez ID: 22989 | HGNC ID: HGNC:31073 | Ensembl Gene: ENSG00000144821 | OMIM ID: 609929 |
| Drug and gene relationship at DGIdb | |||
MYH15 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04530 | Tight junction |
Expression of MYH15:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MYH15 | 22989 | 215331_at | 0.0148 | 0.9599 | |
| GSE20347 | MYH15 | 22989 | 215331_at | 0.0798 | 0.3370 | |
| GSE23400 | MYH15 | 22989 | 215331_at | 0.0031 | 0.9133 | |
| GSE26886 | MYH15 | 22989 | 215331_at | -0.0132 | 0.9024 | |
| GSE29001 | MYH15 | 22989 | 215331_at | -0.0775 | 0.5116 | |
| GSE38129 | MYH15 | 22989 | 215331_at | -0.0442 | 0.6120 | |
| GSE45670 | MYH15 | 22989 | 215331_at | 0.0892 | 0.2940 | |
| GSE53622 | MYH15 | 22989 | 7762 | 0.1955 | 0.0879 | |
| GSE53624 | MYH15 | 22989 | 7762 | 0.2601 | 0.0060 | |
| GSE63941 | MYH15 | 22989 | 215331_at | -0.0478 | 0.7666 | |
| GSE77861 | MYH15 | 22989 | 215331_at | -0.0605 | 0.6001 | |
| TCGA | MYH15 | 22989 | RNAseq | -1.0097 | 0.0907 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MYH15 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MYH15:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MYH15 | 22989 | 17 | 1 | 12 | |
| GSE20123 | MYH15 | 22989 | 16 | 1 | 13 | |
| GSE43470 | MYH15 | 22989 | 18 | 1 | 24 | |
| GSE46452 | MYH15 | 22989 | 12 | 6 | 41 | |
| GSE47630 | MYH15 | 22989 | 16 | 6 | 18 | |
| GSE54993 | MYH15 | 22989 | 2 | 5 | 63 | |
| GSE54994 | MYH15 | 22989 | 28 | 5 | 20 | |
| GSE60625 | MYH15 | 22989 | 0 | 6 | 5 | |
| GSE74703 | MYH15 | 22989 | 15 | 1 | 20 | |
| GSE74704 | MYH15 | 22989 | 13 | 1 | 6 | |
| TCGA | MYH15 | 22989 | 50 | 8 | 38 |
Total number of gains: 187; Total number of losses: 41; Total Number of normals: 260.
Somatic mutations of MYH15:
Generating mutation plots.
Highly correlated genes for MYH15:
Showing top 20/248 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MYH15 | CPNE6 | 0.662675 | 3 | 0 | 3 |
| MYH15 | CHST4 | 0.647665 | 3 | 0 | 3 |
| MYH15 | SLC2A5 | 0.645371 | 3 | 0 | 3 |
| MYH15 | BCAN | 0.644699 | 4 | 0 | 3 |
| MYH15 | KIR3DL3 | 0.637997 | 4 | 0 | 4 |
| MYH15 | NTRK3 | 0.633356 | 4 | 0 | 3 |
| MYH15 | LUZP4 | 0.631865 | 4 | 0 | 4 |
| MYH15 | TAS2R4 | 0.629795 | 4 | 0 | 3 |
| MYH15 | ADCYAP1R1 | 0.629091 | 4 | 0 | 4 |
| MYH15 | POU5F1B | 0.623637 | 3 | 0 | 3 |
| MYH15 | TRPM3 | 0.622522 | 4 | 0 | 3 |
| MYH15 | NEURL1 | 0.621955 | 4 | 0 | 3 |
| MYH15 | OR10H3 | 0.619924 | 4 | 0 | 3 |
| MYH15 | HRG | 0.61642 | 4 | 0 | 3 |
| MYH15 | NEUROD2 | 0.611326 | 4 | 0 | 3 |
| MYH15 | RUNX2 | 0.610322 | 4 | 0 | 4 |
| MYH15 | ACKR2 | 0.610203 | 3 | 0 | 3 |
| MYH15 | PLCB2 | 0.607731 | 3 | 0 | 3 |
| MYH15 | NRP2 | 0.605864 | 4 | 0 | 3 |
| MYH15 | INE1 | 0.605482 | 4 | 0 | 3 |
For details and further investigation, click here
