PHAX

 

Full name: phosphorylated adaptor for RNA export Alias Symbol: FLJ13193
Type: protein-coding gene Cytoband: 5q23.2
Entrez ID: 51808 HGNC ID: HGNC:10241 Ensembl Gene: ENSG00000164902 OMIM ID: 604924
Drug and gene relationship at DGIdb

 

Expression of PHAX:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PHAX 51808 234405_s_at -0.2672 0.6404
GSE26886 PHAX 51808 235767_x_at 0.1906 0.5137
GSE45670 PHAX 51808 235767_x_at -0.2499 0.1076
GSE53622 PHAX 51808 6243 -0.2355 0.0000
GSE53624 PHAX 51808 6243 -0.0886 0.0839
GSE63941 PHAX 51808 235767_x_at -1.0859 0.0252
GSE77861 PHAX 51808 231812_x_at -0.1458 0.3974
GSE97050 PHAX 51808 A_23_P213908 -0.1181 0.5883
SRP007169 PHAX 51808 RNAseq 0.4564 0.3464
SRP008496 PHAX 51808 RNAseq 0.3039 0.3853
SRP064894 PHAX 51808 RNAseq -0.0942 0.2620
SRP133303 PHAX 51808 RNAseq 0.1613 0.2498
SRP159526 PHAX 51808 RNAseq -0.4381 0.0882
SRP193095 PHAX 51808 RNAseq -0.4100 0.0000
SRP219564 PHAX 51808 RNAseq -0.4670 0.1024
TCGA PHAX 51808 RNAseq -0.0313 0.5743

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by PHAX expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of PHAX:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PHAX 51808 1 12 17
GSE20123 PHAX 51808 1 12 17
GSE43470 PHAX 51808 3 8 32
GSE46452 PHAX 51808 0 27 32
GSE47630 PHAX 51808 0 21 19
GSE54993 PHAX 51808 9 1 60
GSE54994 PHAX 51808 2 15 36
GSE60625 PHAX 51808 0 0 11
GSE74703 PHAX 51808 2 6 28
GSE74704 PHAX 51808 1 6 13
TCGA PHAX 51808 2 40 54

Total number of gains: 21; Total number of losses: 148; Total Number of normals: 319.  


 

Somatic mutations of PHAX:

 

Generating mutation plots.

 

Highly correlated genes for PHAX:

 

Showing top 20/37 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PHAXMYO1C0.702146404
PHAXZNF4440.692756303
PHAXCUL4A0.690429303
PHAXARSA0.651298303
PHAXLIAS0.648983403
PHAXMOB20.636905303
PHAXNCKAP50.633799404
PHAXSHROOM10.628124403
PHAXDNASE10.615535404
PHAXGRIA30.608159303
PHAXLUZP10.607165403
PHAXZNF5680.603872403
PHAXNAA160.603322303
PHAXPLXDC20.5939303
PHAXGRK40.591031503
PHAXTRAPPC130.589206604
PHAXYIPF50.585701604
PHAXSHISA30.577562504
PHAXCOQ60.576086403
PHAXNUDT60.574006403

For details and further investigation, click here