| Full name: KN motif and ankyrin repeat domains 4 | Alias Symbol: KIAA0172 | ||
| Type: protein-coding gene | Cytoband: 1p31.3 | ||
| Entrez ID: 163782 | HGNC ID: HGNC:27263 | Ensembl Gene: ENSG00000132854 | OMIM ID: 614612 |
| Drug and gene relationship at DGIdb | |||
Expression of KANK4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KANK4 | 163782 | 229125_at | 1.3326 | 0.2725 | |
| GSE26886 | KANK4 | 163782 | 229125_at | 1.2146 | 0.0006 | |
| GSE45670 | KANK4 | 163782 | 229125_at | 0.4653 | 0.4848 | |
| GSE53622 | KANK4 | 163782 | 63591 | 1.4969 | 0.0000 | |
| GSE53624 | KANK4 | 163782 | 63591 | 1.8280 | 0.0000 | |
| GSE63941 | KANK4 | 163782 | 229125_at | 0.1083 | 0.8936 | |
| GSE77861 | KANK4 | 163782 | 229125_at | 0.0395 | 0.8415 | |
| GSE97050 | KANK4 | 163782 | A_32_P51237 | 0.8332 | 0.1752 | |
| SRP064894 | KANK4 | 163782 | RNAseq | 2.0308 | 0.0000 | |
| SRP133303 | KANK4 | 163782 | RNAseq | 0.9567 | 0.0088 | |
| SRP159526 | KANK4 | 163782 | RNAseq | 2.3867 | 0.0146 | |
| SRP193095 | KANK4 | 163782 | RNAseq | 0.8952 | 0.0004 | |
| TCGA | KANK4 | 163782 | RNAseq | 0.0407 | 0.9017 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by KANK4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KANK4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KANK4 | 163782 | 3 | 6 | 21 | |
| GSE20123 | KANK4 | 163782 | 3 | 5 | 22 | |
| GSE43470 | KANK4 | 163782 | 5 | 2 | 36 | |
| GSE46452 | KANK4 | 163782 | 1 | 1 | 57 | |
| GSE47630 | KANK4 | 163782 | 8 | 5 | 27 | |
| GSE54993 | KANK4 | 163782 | 0 | 0 | 70 | |
| GSE54994 | KANK4 | 163782 | 6 | 4 | 43 | |
| GSE60625 | KANK4 | 163782 | 0 | 0 | 11 | |
| GSE74703 | KANK4 | 163782 | 4 | 2 | 30 | |
| GSE74704 | KANK4 | 163782 | 2 | 2 | 16 | |
| TCGA | KANK4 | 163782 | 10 | 21 | 65 |
Total number of gains: 42; Total number of losses: 48; Total Number of normals: 398.
Somatic mutations of KANK4:
Generating mutation plots.
Highly correlated genes for KANK4:
Showing top 20/734 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KANK4 | XAB2 | 0.778167 | 3 | 0 | 3 |
| KANK4 | C6orf141 | 0.752873 | 4 | 0 | 4 |
| KANK4 | ADCY3 | 0.741744 | 3 | 0 | 3 |
| KANK4 | KIF3A | 0.738087 | 3 | 0 | 3 |
| KANK4 | BORA | 0.73406 | 3 | 0 | 3 |
| KANK4 | STEAP1B | 0.729423 | 3 | 0 | 3 |
| KANK4 | IRAK3 | 0.72783 | 3 | 0 | 3 |
| KANK4 | STK17A | 0.726557 | 4 | 0 | 4 |
| KANK4 | CDCA2 | 0.725137 | 3 | 0 | 3 |
| KANK4 | TNNT1 | 0.72407 | 4 | 0 | 4 |
| KANK4 | KHNYN | 0.720788 | 3 | 0 | 3 |
| KANK4 | TNFRSF10D | 0.71975 | 4 | 0 | 3 |
| KANK4 | ZCCHC24 | 0.716958 | 3 | 0 | 3 |
| KANK4 | A1BG | 0.715937 | 3 | 0 | 3 |
| KANK4 | MAPK1IP1L | 0.71238 | 3 | 0 | 3 |
| KANK4 | MYO3B | 0.711044 | 3 | 0 | 3 |
| KANK4 | SCAMP1 | 0.708195 | 3 | 0 | 3 |
| KANK4 | TECPR2 | 0.706764 | 3 | 0 | 3 |
| KANK4 | SPINK6 | 0.703776 | 3 | 0 | 3 |
| KANK4 | CYP26B1 | 0.703423 | 4 | 0 | 3 |
For details and further investigation, click here
