| Full name: myozenin 2 | Alias Symbol: CS-1|FATZ-2 | ||
| Type: protein-coding gene | Cytoband: 4q26 | ||
| Entrez ID: 51778 | HGNC ID: HGNC:1330 | Ensembl Gene: ENSG00000172399 | OMIM ID: 605602 |
| Drug and gene relationship at DGIdb | |||
Expression of MYOZ2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MYOZ2 | 51778 | 207148_x_at | -0.3346 | 0.4044 | |
| GSE20347 | MYOZ2 | 51778 | 207148_x_at | 0.0528 | 0.5210 | |
| GSE23400 | MYOZ2 | 51778 | 207148_x_at | -0.0783 | 0.0087 | |
| GSE26886 | MYOZ2 | 51778 | 207148_x_at | -0.0612 | 0.6460 | |
| GSE29001 | MYOZ2 | 51778 | 207148_x_at | -0.2058 | 0.0699 | |
| GSE38129 | MYOZ2 | 51778 | 207148_x_at | -0.1241 | 0.1332 | |
| GSE45670 | MYOZ2 | 51778 | 207148_x_at | -0.1908 | 0.0330 | |
| GSE53622 | MYOZ2 | 51778 | 123154 | -0.6375 | 0.0000 | |
| GSE53624 | MYOZ2 | 51778 | 123154 | -0.4802 | 0.0000 | |
| GSE63941 | MYOZ2 | 51778 | 207148_x_at | 0.1418 | 0.3144 | |
| GSE77861 | MYOZ2 | 51778 | 211476_at | 0.0378 | 0.6500 | |
| TCGA | MYOZ2 | 51778 | RNAseq | -2.4330 | 0.0013 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by MYOZ2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MYOZ2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MYOZ2 | 51778 | 1 | 13 | 16 | |
| GSE20123 | MYOZ2 | 51778 | 1 | 13 | 16 | |
| GSE43470 | MYOZ2 | 51778 | 0 | 13 | 30 | |
| GSE46452 | MYOZ2 | 51778 | 1 | 36 | 22 | |
| GSE47630 | MYOZ2 | 51778 | 0 | 22 | 18 | |
| GSE54993 | MYOZ2 | 51778 | 9 | 0 | 61 | |
| GSE54994 | MYOZ2 | 51778 | 1 | 10 | 42 | |
| GSE60625 | MYOZ2 | 51778 | 0 | 1 | 10 | |
| GSE74703 | MYOZ2 | 51778 | 0 | 11 | 25 | |
| GSE74704 | MYOZ2 | 51778 | 0 | 7 | 13 | |
| TCGA | MYOZ2 | 51778 | 9 | 34 | 53 |
Total number of gains: 22; Total number of losses: 160; Total Number of normals: 306.
Somatic mutations of MYOZ2:
Generating mutation plots.
Highly correlated genes for MYOZ2:
Showing top 20/229 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MYOZ2 | GRIN3A | 0.699279 | 3 | 0 | 3 |
| MYOZ2 | ZNF358 | 0.656749 | 3 | 0 | 3 |
| MYOZ2 | DMPK | 0.643069 | 4 | 0 | 3 |
| MYOZ2 | NT5DC3 | 0.640145 | 3 | 0 | 3 |
| MYOZ2 | LONRF3 | 0.639943 | 4 | 0 | 3 |
| MYOZ2 | GRIA1 | 0.638751 | 4 | 0 | 3 |
| MYOZ2 | CHRNA1 | 0.63537 | 3 | 0 | 3 |
| MYOZ2 | STXBP6 | 0.631266 | 4 | 0 | 3 |
| MYOZ2 | LGI2 | 0.629123 | 4 | 0 | 4 |
| MYOZ2 | TBC1D1 | 0.628609 | 3 | 0 | 3 |
| MYOZ2 | SNX32 | 0.626864 | 4 | 0 | 3 |
| MYOZ2 | TM4SF4 | 0.618857 | 6 | 0 | 4 |
| MYOZ2 | COL4A6 | 0.616202 | 3 | 0 | 3 |
| MYOZ2 | OR10H3 | 0.613243 | 7 | 0 | 6 |
| MYOZ2 | CADPS2 | 0.611964 | 4 | 0 | 3 |
| MYOZ2 | C3orf18 | 0.609172 | 4 | 0 | 3 |
| MYOZ2 | FHAD1 | 0.606498 | 3 | 0 | 3 |
| MYOZ2 | ESRRG | 0.605483 | 5 | 0 | 3 |
| MYOZ2 | PGR | 0.602597 | 5 | 0 | 3 |
| MYOZ2 | LUZP4 | 0.598645 | 7 | 0 | 5 |
For details and further investigation, click here
