| Full name: collagen type IV alpha 6 chain | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: Xq22.3 | ||
| Entrez ID: 1288 | HGNC ID: HGNC:2208 | Ensembl Gene: ENSG00000197565 | OMIM ID: 303631 |
| Drug and gene relationship at DGIdb | |||
COL4A6 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04151 | PI3K-Akt signaling pathway | |
| hsa04510 | Focal adhesion | |
| hsa05200 | Pathways in cancer | |
| hsa05222 | Small cell lung cancer |
Expression of COL4A6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COL4A6 | 1288 | 213992_at | -0.4604 | 0.8368 | |
| GSE20347 | COL4A6 | 1288 | 213992_at | 1.0784 | 0.0351 | |
| GSE23400 | COL4A6 | 1288 | 213992_at | -0.0752 | 0.8140 | |
| GSE26886 | COL4A6 | 1288 | 213992_at | 4.5451 | 0.0000 | |
| GSE29001 | COL4A6 | 1288 | 213992_at | 0.8888 | 0.1436 | |
| GSE38129 | COL4A6 | 1288 | 213992_at | 0.1381 | 0.8389 | |
| GSE45670 | COL4A6 | 1288 | 213992_at | -0.3133 | 0.7237 | |
| GSE53622 | COL4A6 | 1288 | 23082 | 0.7969 | 0.0054 | |
| GSE53624 | COL4A6 | 1288 | 23082 | 1.0525 | 0.0000 | |
| GSE63941 | COL4A6 | 1288 | 213992_at | 1.6319 | 0.1860 | |
| GSE77861 | COL4A6 | 1288 | 213992_at | 1.5526 | 0.0347 | |
| GSE97050 | COL4A6 | 1288 | A_23_P217379 | -1.3962 | 0.1858 | |
| SRP007169 | COL4A6 | 1288 | RNAseq | 4.5831 | 0.0000 | |
| SRP008496 | COL4A6 | 1288 | RNAseq | 4.8553 | 0.0000 | |
| SRP064894 | COL4A6 | 1288 | RNAseq | 0.9462 | 0.0102 | |
| SRP133303 | COL4A6 | 1288 | RNAseq | 0.7095 | 0.4145 | |
| SRP159526 | COL4A6 | 1288 | RNAseq | 1.5094 | 0.0625 | |
| SRP193095 | COL4A6 | 1288 | RNAseq | 1.9049 | 0.0000 | |
| SRP219564 | COL4A6 | 1288 | RNAseq | 0.3683 | 0.7797 | |
| TCGA | COL4A6 | 1288 | RNAseq | -0.0804 | 0.7068 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by COL4A6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COL4A6:
No record found for this gene.
Somatic mutations of COL4A6:
Generating mutation plots.
Highly correlated genes for COL4A6:
Showing top 20/383 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COL4A6 | COL4A5 | 0.77119 | 13 | 0 | 13 |
| COL4A6 | CDH19 | 0.749395 | 4 | 0 | 4 |
| COL4A6 | TNIK | 0.734886 | 3 | 0 | 3 |
| COL4A6 | SP4 | 0.733626 | 3 | 0 | 3 |
| COL4A6 | GABRA5 | 0.715796 | 4 | 0 | 3 |
| COL4A6 | ADAMTSL1 | 0.714575 | 3 | 0 | 3 |
| COL4A6 | ZCRB1 | 0.696388 | 4 | 0 | 4 |
| COL4A6 | ADAMTSL3 | 0.683505 | 4 | 0 | 4 |
| COL4A6 | C9orf24 | 0.67944 | 3 | 0 | 3 |
| COL4A6 | FXYD1 | 0.672818 | 4 | 0 | 4 |
| COL4A6 | MARVELD1 | 0.669717 | 7 | 0 | 7 |
| COL4A6 | TAF1 | 0.668483 | 3 | 0 | 3 |
| COL4A6 | STK17A | 0.666952 | 3 | 0 | 3 |
| COL4A6 | FOXF2 | 0.666037 | 11 | 0 | 10 |
| COL4A6 | PPP1R12B | 0.664158 | 4 | 0 | 4 |
| COL4A6 | CAP2 | 0.662566 | 5 | 0 | 4 |
| COL4A6 | ANGPTL7 | 0.660877 | 4 | 0 | 3 |
| COL4A6 | PRKACB | 0.659586 | 3 | 0 | 3 |
| COL4A6 | DNAJC18 | 0.658914 | 3 | 0 | 3 |
| COL4A6 | MAGI2 | 0.65839 | 4 | 0 | 4 |
For details and further investigation, click here
