| Full name: N-acetylated alpha-linked acidic dipeptidase 2 | Alias Symbol: NAALADASE2|GCPIII | ||
| Type: protein-coding gene | Cytoband: 11q14.3 | ||
| Entrez ID: 10003 | HGNC ID: HGNC:14526 | Ensembl Gene: ENSG00000077616 | OMIM ID: 611636 |
| Drug and gene relationship at DGIdb | |||
Expression of NAALAD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NAALAD2 | 10003 | 233815_at | 0.0136 | 0.9661 | |
| GSE20347 | NAALAD2 | 10003 | 222161_at | -0.0039 | 0.9562 | |
| GSE23400 | NAALAD2 | 10003 | 222161_at | -0.0903 | 0.0000 | |
| GSE26886 | NAALAD2 | 10003 | 233815_at | 0.0647 | 0.4781 | |
| GSE29001 | NAALAD2 | 10003 | 222161_at | -0.0617 | 0.6762 | |
| GSE38129 | NAALAD2 | 10003 | 222161_at | -0.2187 | 0.0662 | |
| GSE45670 | NAALAD2 | 10003 | 233815_at | -0.0338 | 0.7185 | |
| GSE53622 | NAALAD2 | 10003 | 54613 | -0.4134 | 0.0029 | |
| GSE53624 | NAALAD2 | 10003 | 54613 | -0.7474 | 0.0000 | |
| GSE63941 | NAALAD2 | 10003 | 222161_at | -0.3476 | 0.0788 | |
| GSE77861 | NAALAD2 | 10003 | 233815_at | -0.0691 | 0.4420 | |
| GSE97050 | NAALAD2 | 10003 | A_23_P161583 | -0.2795 | 0.2577 | |
| SRP064894 | NAALAD2 | 10003 | RNAseq | -0.7025 | 0.0375 | |
| SRP133303 | NAALAD2 | 10003 | RNAseq | -1.1211 | 0.0000 | |
| SRP159526 | NAALAD2 | 10003 | RNAseq | -0.8309 | 0.0722 | |
| SRP193095 | NAALAD2 | 10003 | RNAseq | -0.1129 | 0.6061 | |
| SRP219564 | NAALAD2 | 10003 | RNAseq | -1.1758 | 0.0659 | |
| TCGA | NAALAD2 | 10003 | RNAseq | -0.5043 | 0.0297 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by NAALAD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NAALAD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NAALAD2 | 10003 | 3 | 10 | 17 | |
| GSE20123 | NAALAD2 | 10003 | 3 | 10 | 17 | |
| GSE43470 | NAALAD2 | 10003 | 3 | 4 | 36 | |
| GSE46452 | NAALAD2 | 10003 | 6 | 23 | 30 | |
| GSE47630 | NAALAD2 | 10003 | 2 | 19 | 19 | |
| GSE54993 | NAALAD2 | 10003 | 8 | 2 | 60 | |
| GSE54994 | NAALAD2 | 10003 | 5 | 19 | 29 | |
| GSE60625 | NAALAD2 | 10003 | 0 | 3 | 8 | |
| GSE74703 | NAALAD2 | 10003 | 2 | 3 | 31 | |
| GSE74704 | NAALAD2 | 10003 | 3 | 6 | 11 | |
| TCGA | NAALAD2 | 10003 | 14 | 40 | 42 |
Total number of gains: 49; Total number of losses: 139; Total Number of normals: 300.
Somatic mutations of NAALAD2:
Generating mutation plots.
Highly correlated genes for NAALAD2:
Showing top 20/200 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NAALAD2 | AGT | 0.742484 | 3 | 0 | 3 |
| NAALAD2 | ZNF585A | 0.724046 | 3 | 0 | 3 |
| NAALAD2 | VEGFB | 0.71706 | 3 | 0 | 3 |
| NAALAD2 | DYNC1I2 | 0.716069 | 3 | 0 | 3 |
| NAALAD2 | ZNF780B | 0.677634 | 3 | 0 | 3 |
| NAALAD2 | ZBTB16 | 0.673261 | 4 | 0 | 3 |
| NAALAD2 | C1QTNF7 | 0.670572 | 3 | 0 | 3 |
| NAALAD2 | KCTD6 | 0.663577 | 4 | 0 | 4 |
| NAALAD2 | CRTAP | 0.651088 | 4 | 0 | 4 |
| NAALAD2 | RARA | 0.646055 | 3 | 0 | 3 |
| NAALAD2 | ITM2C | 0.638925 | 3 | 0 | 3 |
| NAALAD2 | RSF1 | 0.634587 | 4 | 0 | 3 |
| NAALAD2 | TIMP4 | 0.633122 | 6 | 0 | 5 |
| NAALAD2 | ZNF609 | 0.632031 | 4 | 0 | 3 |
| NAALAD2 | PREX2 | 0.629315 | 4 | 0 | 3 |
| NAALAD2 | KCNT2 | 0.624776 | 4 | 0 | 4 |
| NAALAD2 | NIPSNAP3B | 0.624684 | 6 | 0 | 4 |
| NAALAD2 | MRPL2 | 0.621437 | 4 | 0 | 3 |
| NAALAD2 | RGN | 0.619939 | 5 | 0 | 5 |
| NAALAD2 | PRELP | 0.618416 | 6 | 0 | 4 |
For details and further investigation, click here
