ZNF609

 

Full name: zinc finger protein 609 Alias Symbol: KIAA0295
Type: protein-coding gene Cytoband: 15q22.1
Entrez ID: 23060 HGNC ID: HGNC:29003 Ensembl Gene: ENSG00000180357 OMIM ID: 617474
Drug and gene relationship at DGIdb

 

Expression of ZNF609:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ZNF609 23060 212620_at -0.1236 0.7753
GSE20347 ZNF609 23060 212620_at 0.1165 0.1723
GSE23400 ZNF609 23060 212620_at -0.0829 0.0402
GSE26886 ZNF609 23060 212620_at 0.1640 0.3828
GSE29001 ZNF609 23060 212620_at 0.3552 0.0962
GSE38129 ZNF609 23060 212620_at -0.0227 0.9171
GSE45670 ZNF609 23060 212620_at 0.1972 0.2057
GSE53622 ZNF609 23060 61023 0.3334 0.0000
GSE53624 ZNF609 23060 61023 0.4258 0.0000
GSE63941 ZNF609 23060 212620_at -0.0264 0.9381
GSE77861 ZNF609 23060 212620_at 0.1248 0.3768
GSE97050 ZNF609 23060 A_24_P145047 -0.0508 0.8525
SRP007169 ZNF609 23060 RNAseq 1.2686 0.0028
SRP008496 ZNF609 23060 RNAseq 1.2495 0.0001
SRP064894 ZNF609 23060 RNAseq 0.3603 0.1146
SRP133303 ZNF609 23060 RNAseq 0.1883 0.0554
SRP159526 ZNF609 23060 RNAseq 0.1242 0.6157
SRP193095 ZNF609 23060 RNAseq 0.3415 0.0015
SRP219564 ZNF609 23060 RNAseq 0.0530 0.8748
TCGA ZNF609 23060 RNAseq -0.0535 0.2476

Upregulated datasets: 2; Downregulated datasets: 0.  


 

Survival by ZNF609 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ZNF609:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ZNF609 23060 7 4 19
GSE20123 ZNF609 23060 7 4 19
GSE43470 ZNF609 23060 4 6 33
GSE46452 ZNF609 23060 3 7 49
GSE47630 ZNF609 23060 8 10 22
GSE54993 ZNF609 23060 5 6 59
GSE54994 ZNF609 23060 6 7 40
GSE60625 ZNF609 23060 4 0 7
GSE74703 ZNF609 23060 4 3 29
GSE74704 ZNF609 23060 3 4 13
TCGA ZNF609 23060 10 17 69

Total number of gains: 61; Total number of losses: 68; Total Number of normals: 359.  


 

Somatic mutations of ZNF609:

 

Generating mutation plots.

 

Highly correlated genes for ZNF609:

 

Showing top 20/296 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ZNF609GRIN3B0.803607303
ZNF609OLFML10.782631303
ZNF609FRZB0.770854303
ZNF609MYH30.766556303
ZNF609KLC10.762452303
ZNF609RNF1150.758651303
ZNF609JUND0.752174303
ZNF609MOAP10.751784303
ZNF609SETD30.74616303
ZNF609NFASC0.744204303
ZNF609TAF30.743369303
ZNF609DMPK0.737704303
ZNF609NES0.737267303
ZNF609SH3GL20.734081303
ZNF609HNRNPL0.727284303
ZNF609PNMA10.71837303
ZNF609IRF2BP20.714371403
ZNF609KIAA12570.711057303
ZNF609SVEP10.709982303
ZNF609SYNC0.705149303

For details and further investigation, click here