| Full name: necdin, MAGE family member | Alias Symbol: HsT16328|PWCR | ||
| Type: protein-coding gene | Cytoband: 15q11.2 | ||
| Entrez ID: 4692 | HGNC ID: HGNC:7675 | Ensembl Gene: ENSG00000182636 | OMIM ID: 602117 |
| Drug and gene relationship at DGIdb | |||
Expression of NDN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NDN | 4692 | 209550_at | -0.7826 | 0.4691 | |
| GSE20347 | NDN | 4692 | 209550_at | -0.6080 | 0.0685 | |
| GSE23400 | NDN | 4692 | 209550_at | -0.0474 | 0.7467 | |
| GSE26886 | NDN | 4692 | 209550_at | 0.1080 | 0.8201 | |
| GSE29001 | NDN | 4692 | 209550_at | -1.0426 | 0.0936 | |
| GSE38129 | NDN | 4692 | 209550_at | -0.6004 | 0.0567 | |
| GSE45670 | NDN | 4692 | 209550_at | -0.6967 | 0.0494 | |
| GSE53622 | NDN | 4692 | 11744 | -0.4985 | 0.0002 | |
| GSE53624 | NDN | 4692 | 11744 | -0.3665 | 0.0060 | |
| GSE63941 | NDN | 4692 | 209550_at | -5.2943 | 0.0118 | |
| GSE77861 | NDN | 4692 | 209550_at | -0.4497 | 0.4222 | |
| GSE97050 | NDN | 4692 | A_23_P106405 | -0.3711 | 0.2727 | |
| SRP007169 | NDN | 4692 | RNAseq | -0.2119 | 0.7315 | |
| SRP008496 | NDN | 4692 | RNAseq | -0.4493 | 0.2788 | |
| SRP064894 | NDN | 4692 | RNAseq | 0.1417 | 0.6756 | |
| SRP133303 | NDN | 4692 | RNAseq | -0.0925 | 0.5409 | |
| SRP159526 | NDN | 4692 | RNAseq | -0.0048 | 0.9896 | |
| SRP193095 | NDN | 4692 | RNAseq | 0.3019 | 0.1818 | |
| SRP219564 | NDN | 4692 | RNAseq | -0.4264 | 0.5786 | |
| TCGA | NDN | 4692 | RNAseq | -0.1591 | 0.2599 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by NDN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NDN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NDN | 4692 | 3 | 7 | 20 | |
| GSE20123 | NDN | 4692 | 2 | 7 | 21 | |
| GSE43470 | NDN | 4692 | 3 | 5 | 35 | |
| GSE46452 | NDN | 4692 | 3 | 7 | 49 | |
| GSE47630 | NDN | 4692 | 8 | 11 | 21 | |
| GSE54993 | NDN | 4692 | 4 | 6 | 60 | |
| GSE54994 | NDN | 4692 | 7 | 6 | 40 | |
| GSE60625 | NDN | 4692 | 4 | 3 | 4 | |
| GSE74703 | NDN | 4692 | 3 | 3 | 30 | |
| GSE74704 | NDN | 4692 | 1 | 5 | 14 | |
| TCGA | NDN | 4692 | 17 | 20 | 59 |
Total number of gains: 55; Total number of losses: 80; Total Number of normals: 353.
Somatic mutations of NDN:
Generating mutation plots.
Highly correlated genes for NDN:
Showing top 20/534 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NDN | RPL41 | 0.797556 | 3 | 0 | 3 |
| NDN | CREBBP | 0.751761 | 3 | 0 | 3 |
| NDN | ZBED5 | 0.74924 | 3 | 0 | 3 |
| NDN | MAP3K8 | 0.743113 | 3 | 0 | 3 |
| NDN | UQCRFS1 | 0.729244 | 4 | 0 | 4 |
| NDN | GPKOW | 0.727792 | 4 | 0 | 4 |
| NDN | ZNF215 | 0.724211 | 4 | 0 | 4 |
| NDN | TPRG1L | 0.717139 | 3 | 0 | 3 |
| NDN | KCND1 | 0.716767 | 3 | 0 | 3 |
| NDN | BCAP29 | 0.716044 | 3 | 0 | 3 |
| NDN | TSHZ3 | 0.715899 | 4 | 0 | 3 |
| NDN | ARIH1 | 0.712646 | 4 | 0 | 3 |
| NDN | FKBP7 | 0.712439 | 3 | 0 | 3 |
| NDN | CTTNBP2NL | 0.702434 | 3 | 0 | 3 |
| NDN | C15orf41 | 0.697039 | 3 | 0 | 3 |
| NDN | APLP2 | 0.695733 | 3 | 0 | 3 |
| NDN | KLHDC2 | 0.692646 | 3 | 0 | 3 |
| NDN | CASP4 | 0.689301 | 3 | 0 | 3 |
| NDN | ATF1 | 0.688452 | 3 | 0 | 3 |
| NDN | CYP4V2 | 0.687866 | 4 | 0 | 4 |
For details and further investigation, click here
