| Full name: tumor protein p63 regulated 1 like | Alias Symbol: RP11-46F15.3|FLJ21811 | ||
| Type: protein-coding gene | Cytoband: 1p36.32 | ||
| Entrez ID: 127262 | HGNC ID: HGNC:27007 | Ensembl Gene: ENSG00000158109 | OMIM ID: 611460 |
| Drug and gene relationship at DGIdb | |||
Expression of TPRG1L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TPRG1L | 127262 | 224871_at | -0.4774 | 0.4593 | |
| GSE26886 | TPRG1L | 127262 | 224871_at | -0.5639 | 0.0237 | |
| GSE45670 | TPRG1L | 127262 | 224871_at | -0.3050 | 0.0693 | |
| GSE53622 | TPRG1L | 127262 | 50154 | -0.2951 | 0.0000 | |
| GSE53624 | TPRG1L | 127262 | 50154 | -0.5272 | 0.0000 | |
| GSE63941 | TPRG1L | 127262 | 224871_at | -0.7741 | 0.1580 | |
| GSE77861 | TPRG1L | 127262 | 224871_at | -0.5417 | 0.0230 | |
| GSE97050 | TPRG1L | 127262 | A_23_P339773 | -0.1387 | 0.4997 | |
| SRP007169 | TPRG1L | 127262 | RNAseq | -2.0064 | 0.0000 | |
| SRP008496 | TPRG1L | 127262 | RNAseq | -1.7505 | 0.0000 | |
| SRP064894 | TPRG1L | 127262 | RNAseq | -0.3350 | 0.0905 | |
| SRP133303 | TPRG1L | 127262 | RNAseq | -0.5091 | 0.0315 | |
| SRP159526 | TPRG1L | 127262 | RNAseq | -0.8606 | 0.0011 | |
| SRP193095 | TPRG1L | 127262 | RNAseq | -0.7499 | 0.0000 | |
| SRP219564 | TPRG1L | 127262 | RNAseq | -0.8986 | 0.0144 | |
| TCGA | TPRG1L | 127262 | RNAseq | -0.1658 | 0.0015 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by TPRG1L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TPRG1L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TPRG1L | 127262 | 4 | 6 | 20 | |
| GSE20123 | TPRG1L | 127262 | 4 | 5 | 21 | |
| GSE43470 | TPRG1L | 127262 | 3 | 5 | 35 | |
| GSE46452 | TPRG1L | 127262 | 7 | 1 | 51 | |
| GSE47630 | TPRG1L | 127262 | 8 | 4 | 28 | |
| GSE54993 | TPRG1L | 127262 | 3 | 2 | 65 | |
| GSE54994 | TPRG1L | 127262 | 14 | 3 | 36 | |
| GSE60625 | TPRG1L | 127262 | 0 | 0 | 11 | |
| GSE74703 | TPRG1L | 127262 | 3 | 3 | 30 | |
| GSE74704 | TPRG1L | 127262 | 4 | 0 | 16 | |
| TCGA | TPRG1L | 127262 | 14 | 20 | 62 |
Total number of gains: 64; Total number of losses: 49; Total Number of normals: 375.
Somatic mutations of TPRG1L:
Generating mutation plots.
Highly correlated genes for TPRG1L:
Showing top 20/980 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TPRG1L | MKRN1 | 0.803642 | 3 | 0 | 3 |
| TPRG1L | KLHDC10 | 0.780502 | 3 | 0 | 3 |
| TPRG1L | RBPJL | 0.780167 | 3 | 0 | 3 |
| TPRG1L | PRDX2 | 0.77303 | 3 | 0 | 3 |
| TPRG1L | VAMP3 | 0.767387 | 8 | 0 | 8 |
| TPRG1L | CIDEB | 0.764335 | 3 | 0 | 3 |
| TPRG1L | VDAC3 | 0.762085 | 3 | 0 | 3 |
| TPRG1L | TOP2B | 0.752933 | 3 | 0 | 3 |
| TPRG1L | NDUFA13 | 0.746021 | 4 | 0 | 4 |
| TPRG1L | ZMPSTE24 | 0.739814 | 3 | 0 | 3 |
| TPRG1L | TP53RK | 0.737824 | 3 | 0 | 3 |
| TPRG1L | CDIPT | 0.736108 | 3 | 0 | 3 |
| TPRG1L | ZNF518A | 0.729159 | 3 | 0 | 3 |
| TPRG1L | GOLGB1 | 0.726672 | 3 | 0 | 3 |
| TPRG1L | KDM3A | 0.722443 | 3 | 0 | 3 |
| TPRG1L | RAD17 | 0.721729 | 3 | 0 | 3 |
| TPRG1L | ERI2 | 0.720343 | 3 | 0 | 3 |
| TPRG1L | AKIRIN1 | 0.718306 | 3 | 0 | 3 |
| TPRG1L | NDN | 0.717139 | 3 | 0 | 3 |
| TPRG1L | NUDT16 | 0.714369 | 3 | 0 | 3 |
For details and further investigation, click here
