| Full name: NDRG family member 4 | Alias Symbol: KIAA1180|SMAP-8 | ||
| Type: protein-coding gene | Cytoband: 16q21 | ||
| Entrez ID: 65009 | HGNC ID: HGNC:14466 | Ensembl Gene: ENSG00000103034 | OMIM ID: 614463 |
| Drug and gene relationship at DGIdb | |||
Expression of NDRG4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NDRG4 | 65009 | 209159_s_at | -0.1286 | 0.9267 | |
| GSE20347 | NDRG4 | 65009 | 209159_s_at | 0.2115 | 0.5767 | |
| GSE23400 | NDRG4 | 65009 | 209159_s_at | -0.1920 | 0.1736 | |
| GSE26886 | NDRG4 | 65009 | 209159_s_at | -0.8570 | 0.0458 | |
| GSE29001 | NDRG4 | 65009 | 209159_s_at | -0.1215 | 0.7183 | |
| GSE38129 | NDRG4 | 65009 | 209159_s_at | 0.5409 | 0.0731 | |
| GSE45670 | NDRG4 | 65009 | 209159_s_at | 0.7696 | 0.0191 | |
| GSE53622 | NDRG4 | 65009 | 50762 | -0.0997 | 0.5291 | |
| GSE53624 | NDRG4 | 65009 | 50762 | -0.2381 | 0.0194 | |
| GSE63941 | NDRG4 | 65009 | 209159_s_at | -0.7906 | 0.2793 | |
| GSE77861 | NDRG4 | 65009 | 209159_s_at | 0.6018 | 0.2689 | |
| GSE97050 | NDRG4 | 65009 | A_23_P140748 | -0.1394 | 0.5912 | |
| SRP007169 | NDRG4 | 65009 | RNAseq | -0.6539 | 0.3921 | |
| SRP008496 | NDRG4 | 65009 | RNAseq | 0.2097 | 0.6859 | |
| SRP064894 | NDRG4 | 65009 | RNAseq | 0.2296 | 0.5871 | |
| SRP133303 | NDRG4 | 65009 | RNAseq | -0.7181 | 0.0747 | |
| SRP159526 | NDRG4 | 65009 | RNAseq | 0.4502 | 0.4578 | |
| SRP193095 | NDRG4 | 65009 | RNAseq | 0.0762 | 0.8177 | |
| SRP219564 | NDRG4 | 65009 | RNAseq | -0.7356 | 0.2590 | |
| TCGA | NDRG4 | 65009 | RNAseq | 0.4614 | 0.0090 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NDRG4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NDRG4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NDRG4 | 65009 | 7 | 0 | 23 | |
| GSE20123 | NDRG4 | 65009 | 7 | 0 | 23 | |
| GSE43470 | NDRG4 | 65009 | 2 | 7 | 34 | |
| GSE46452 | NDRG4 | 65009 | 38 | 1 | 20 | |
| GSE47630 | NDRG4 | 65009 | 10 | 8 | 22 | |
| GSE54993 | NDRG4 | 65009 | 2 | 4 | 64 | |
| GSE54994 | NDRG4 | 65009 | 6 | 10 | 37 | |
| GSE60625 | NDRG4 | 65009 | 4 | 0 | 7 | |
| GSE74703 | NDRG4 | 65009 | 2 | 5 | 29 | |
| GSE74704 | NDRG4 | 65009 | 5 | 0 | 15 | |
| TCGA | NDRG4 | 65009 | 26 | 11 | 59 |
Total number of gains: 109; Total number of losses: 46; Total Number of normals: 333.
Somatic mutations of NDRG4:
Generating mutation plots.
Highly correlated genes for NDRG4:
Showing top 20/95 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NDRG4 | NIT1 | 0.686432 | 3 | 0 | 3 |
| NDRG4 | ZMAT2 | 0.662912 | 3 | 0 | 3 |
| NDRG4 | RNF181 | 0.63675 | 3 | 0 | 3 |
| NDRG4 | STK25 | 0.634829 | 3 | 0 | 3 |
| NDRG4 | STX3 | 0.619997 | 4 | 0 | 3 |
| NDRG4 | CCNE1 | 0.615473 | 3 | 0 | 3 |
| NDRG4 | SUCLG1 | 0.614549 | 3 | 0 | 3 |
| NDRG4 | ELOVL4 | 0.614313 | 4 | 0 | 3 |
| NDRG4 | SCFD1 | 0.602347 | 3 | 0 | 3 |
| NDRG4 | LDHD | 0.600977 | 3 | 0 | 3 |
| NDRG4 | ANKZF1 | 0.59664 | 3 | 0 | 3 |
| NDRG4 | SLC4A1AP | 0.595572 | 3 | 0 | 3 |
| NDRG4 | PELI1 | 0.595156 | 3 | 0 | 3 |
| NDRG4 | IGSF3 | 0.593366 | 4 | 0 | 3 |
| NDRG4 | FAM192A | 0.592639 | 3 | 0 | 3 |
| NDRG4 | WFDC12 | 0.592234 | 4 | 0 | 3 |
| NDRG4 | DOLK | 0.589253 | 5 | 0 | 4 |
| NDRG4 | AFG3L2 | 0.588716 | 4 | 0 | 4 |
| NDRG4 | CCNYL1 | 0.585721 | 3 | 0 | 3 |
| NDRG4 | CAMKMT | 0.578739 | 3 | 0 | 3 |
For details and further investigation, click here
