| Full name: ELOVL fatty acid elongase 4 | Alias Symbol: CT118 | ||
| Type: protein-coding gene | Cytoband: 6q14.1 | ||
| Entrez ID: 6785 | HGNC ID: HGNC:14415 | Ensembl Gene: ENSG00000118402 | OMIM ID: 605512 |
| Drug and gene relationship at DGIdb | |||
Expression of ELOVL4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ELOVL4 | 6785 | 219532_at | -1.2337 | 0.3314 | |
| GSE20347 | ELOVL4 | 6785 | 219532_at | -2.1517 | 0.0000 | |
| GSE23400 | ELOVL4 | 6785 | 219532_at | -0.6211 | 0.0000 | |
| GSE26886 | ELOVL4 | 6785 | 219532_at | -2.2226 | 0.0001 | |
| GSE29001 | ELOVL4 | 6785 | 219532_at | -1.6368 | 0.0085 | |
| GSE38129 | ELOVL4 | 6785 | 219532_at | -1.5368 | 0.0000 | |
| GSE45670 | ELOVL4 | 6785 | 219532_at | -1.1759 | 0.0159 | |
| GSE53622 | ELOVL4 | 6785 | 142677 | -1.7196 | 0.0000 | |
| GSE53624 | ELOVL4 | 6785 | 142677 | -1.5900 | 0.0000 | |
| GSE63941 | ELOVL4 | 6785 | 219532_at | -2.3098 | 0.0164 | |
| GSE77861 | ELOVL4 | 6785 | 219532_at | -0.5198 | 0.3260 | |
| GSE97050 | ELOVL4 | 6785 | A_23_P82065 | 0.1627 | 0.4136 | |
| SRP007169 | ELOVL4 | 6785 | RNAseq | -2.3724 | 0.0002 | |
| SRP008496 | ELOVL4 | 6785 | RNAseq | -2.0858 | 0.0017 | |
| SRP064894 | ELOVL4 | 6785 | RNAseq | -1.1702 | 0.0011 | |
| SRP133303 | ELOVL4 | 6785 | RNAseq | -0.7542 | 0.0610 | |
| SRP159526 | ELOVL4 | 6785 | RNAseq | -1.5637 | 0.0018 | |
| SRP219564 | ELOVL4 | 6785 | RNAseq | -2.7031 | 0.0003 | |
| TCGA | ELOVL4 | 6785 | RNAseq | 0.2079 | 0.2524 |
Upregulated datasets: 0; Downregulated datasets: 13.
Survival by ELOVL4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ELOVL4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ELOVL4 | 6785 | 1 | 4 | 25 | |
| GSE20123 | ELOVL4 | 6785 | 1 | 3 | 26 | |
| GSE43470 | ELOVL4 | 6785 | 2 | 1 | 40 | |
| GSE46452 | ELOVL4 | 6785 | 3 | 11 | 45 | |
| GSE47630 | ELOVL4 | 6785 | 8 | 6 | 26 | |
| GSE54993 | ELOVL4 | 6785 | 3 | 2 | 65 | |
| GSE54994 | ELOVL4 | 6785 | 8 | 7 | 38 | |
| GSE60625 | ELOVL4 | 6785 | 0 | 1 | 10 | |
| GSE74703 | ELOVL4 | 6785 | 2 | 1 | 33 | |
| GSE74704 | ELOVL4 | 6785 | 0 | 2 | 18 | |
| TCGA | ELOVL4 | 6785 | 6 | 21 | 69 |
Total number of gains: 34; Total number of losses: 59; Total Number of normals: 395.
Somatic mutations of ELOVL4:
Generating mutation plots.
Highly correlated genes for ELOVL4:
Showing top 20/814 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ELOVL4 | CWH43 | 0.741113 | 9 | 0 | 9 |
| ELOVL4 | CRCT1 | 0.733389 | 10 | 0 | 10 |
| ELOVL4 | LTA4H | 0.730128 | 3 | 0 | 3 |
| ELOVL4 | PRSS3 | 0.713512 | 10 | 0 | 10 |
| ELOVL4 | MXD1 | 0.711821 | 10 | 0 | 10 |
| ELOVL4 | CNFN | 0.703888 | 6 | 0 | 6 |
| ELOVL4 | SPAG17 | 0.701415 | 4 | 0 | 3 |
| ELOVL4 | UPK3B | 0.687481 | 3 | 0 | 3 |
| ELOVL4 | PIM1 | 0.685884 | 10 | 0 | 10 |
| ELOVL4 | ATG9B | 0.683964 | 7 | 0 | 7 |
| ELOVL4 | PMM1 | 0.683826 | 11 | 0 | 10 |
| ELOVL4 | YOD1 | 0.680138 | 11 | 0 | 10 |
| ELOVL4 | TOM1 | 0.678918 | 11 | 0 | 10 |
| ELOVL4 | SNX24 | 0.674549 | 11 | 0 | 10 |
| ELOVL4 | SPINK7 | 0.672663 | 6 | 0 | 5 |
| ELOVL4 | TGM1 | 0.67257 | 11 | 0 | 10 |
| ELOVL4 | VPS4B | 0.67238 | 10 | 0 | 8 |
| ELOVL4 | IL18 | 0.672293 | 10 | 0 | 10 |
| ELOVL4 | FNDC4 | 0.670495 | 11 | 0 | 10 |
| ELOVL4 | EPGN | 0.670184 | 3 | 0 | 3 |
For details and further investigation, click here
