| Full name: serine/threonine kinase 25 | Alias Symbol: SOK1|YSK1 | ||
| Type: protein-coding gene | Cytoband: 2q37.3 | ||
| Entrez ID: 10494 | HGNC ID: HGNC:11404 | Ensembl Gene: ENSG00000115694 | OMIM ID: 602255 |
| Drug and gene relationship at DGIdb | |||
Expression of STK25:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STK25 | 10494 | 201314_at | 0.0683 | 0.8631 | |
| GSE20347 | STK25 | 10494 | 201314_at | -0.1254 | 0.4307 | |
| GSE23400 | STK25 | 10494 | 201314_at | 0.1111 | 0.0547 | |
| GSE26886 | STK25 | 10494 | 201314_at | -0.4681 | 0.0144 | |
| GSE29001 | STK25 | 10494 | 201314_at | 0.1262 | 0.3757 | |
| GSE38129 | STK25 | 10494 | 201314_at | -0.0674 | 0.6028 | |
| GSE45670 | STK25 | 10494 | 201314_at | 0.2296 | 0.0503 | |
| GSE53622 | STK25 | 10494 | 63744 | 0.0326 | 0.5778 | |
| GSE53624 | STK25 | 10494 | 63744 | 0.0557 | 0.3842 | |
| GSE63941 | STK25 | 10494 | 201314_at | -0.4470 | 0.3141 | |
| GSE77861 | STK25 | 10494 | 201314_at | 0.1942 | 0.3681 | |
| GSE97050 | STK25 | 10494 | A_23_P252653 | 0.2227 | 0.4343 | |
| SRP007169 | STK25 | 10494 | RNAseq | -0.3816 | 0.1785 | |
| SRP008496 | STK25 | 10494 | RNAseq | -0.3243 | 0.0298 | |
| SRP064894 | STK25 | 10494 | RNAseq | 0.3752 | 0.0389 | |
| SRP133303 | STK25 | 10494 | RNAseq | 0.0559 | 0.7089 | |
| SRP159526 | STK25 | 10494 | RNAseq | 0.1083 | 0.7066 | |
| SRP193095 | STK25 | 10494 | RNAseq | 0.0026 | 0.9780 | |
| SRP219564 | STK25 | 10494 | RNAseq | -0.0394 | 0.8770 | |
| TCGA | STK25 | 10494 | RNAseq | -0.0427 | 0.3412 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by STK25 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STK25:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STK25 | 10494 | 1 | 12 | 17 | |
| GSE20123 | STK25 | 10494 | 1 | 12 | 17 | |
| GSE43470 | STK25 | 10494 | 1 | 9 | 33 | |
| GSE46452 | STK25 | 10494 | 0 | 5 | 54 | |
| GSE47630 | STK25 | 10494 | 4 | 5 | 31 | |
| GSE54993 | STK25 | 10494 | 4 | 3 | 63 | |
| GSE54994 | STK25 | 10494 | 8 | 9 | 36 | |
| GSE60625 | STK25 | 10494 | 0 | 3 | 8 | |
| GSE74703 | STK25 | 10494 | 1 | 7 | 28 | |
| GSE74704 | STK25 | 10494 | 1 | 5 | 14 | |
| TCGA | STK25 | 10494 | 11 | 29 | 56 |
Total number of gains: 32; Total number of losses: 99; Total Number of normals: 357.
Somatic mutations of STK25:
Generating mutation plots.
Highly correlated genes for STK25:
Showing top 20/54 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STK25 | LMTK2 | 0.661738 | 3 | 0 | 3 |
| STK25 | PGS1 | 0.650244 | 3 | 0 | 3 |
| STK25 | STK11IP | 0.640953 | 7 | 0 | 6 |
| STK25 | NDRG4 | 0.634829 | 3 | 0 | 3 |
| STK25 | FARP2 | 0.628473 | 4 | 0 | 3 |
| STK25 | UBTF | 0.609587 | 4 | 0 | 3 |
| STK25 | ATF6B | 0.607578 | 3 | 0 | 3 |
| STK25 | ILKAP | 0.606055 | 8 | 0 | 6 |
| STK25 | LIMK1 | 0.601373 | 3 | 0 | 3 |
| STK25 | CWC25 | 0.59844 | 3 | 0 | 3 |
| STK25 | MTG1 | 0.592817 | 4 | 0 | 4 |
| STK25 | ZNF235 | 0.591828 | 3 | 0 | 3 |
| STK25 | LRFN4 | 0.589394 | 3 | 0 | 3 |
| STK25 | ZKSCAN5 | 0.575691 | 4 | 0 | 3 |
| STK25 | COPS7B | 0.569961 | 7 | 0 | 7 |
| STK25 | DHX58 | 0.564262 | 4 | 0 | 3 |
| STK25 | GNB2 | 0.561696 | 6 | 0 | 4 |
| STK25 | RBM14 | 0.561467 | 5 | 0 | 3 |
| STK25 | L3MBTL2 | 0.560281 | 3 | 0 | 3 |
| STK25 | KCTD11 | 0.559417 | 3 | 0 | 3 |
For details and further investigation, click here
