| Full name: WAP four-disulfide core domain 12 | Alias Symbol: dJ211D12.4|WAP2 | ||
| Type: protein-coding gene | Cytoband: 20q13.12 | ||
| Entrez ID: 128488 | HGNC ID: HGNC:16115 | Ensembl Gene: ENSG00000168703 | OMIM ID: 609872 |
| Drug and gene relationship at DGIdb | |||
Expression of WFDC12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WFDC12 | 128488 | 1553081_at | 0.5359 | 0.6907 | |
| GSE26886 | WFDC12 | 128488 | 1553081_at | -0.6284 | 0.1005 | |
| GSE45670 | WFDC12 | 128488 | 1553081_at | 0.0768 | 0.9229 | |
| GSE53622 | WFDC12 | 128488 | 131003 | -0.6497 | 0.0365 | |
| GSE53624 | WFDC12 | 128488 | 131003 | -0.8129 | 0.0022 | |
| GSE63941 | WFDC12 | 128488 | 1553081_at | 0.1289 | 0.4627 | |
| GSE77861 | WFDC12 | 128488 | 1553081_at | -0.3465 | 0.3105 | |
| GSE97050 | WFDC12 | 128488 | A_23_P68436 | -0.2090 | 0.4865 | |
| SRP007169 | WFDC12 | 128488 | RNAseq | -6.2759 | 0.0002 | |
| SRP064894 | WFDC12 | 128488 | RNAseq | -3.6348 | 0.0000 | |
| SRP133303 | WFDC12 | 128488 | RNAseq | -0.5282 | 0.0643 | |
| SRP193095 | WFDC12 | 128488 | RNAseq | -0.6415 | 0.0299 | |
| TCGA | WFDC12 | 128488 | RNAseq | 1.7345 | 0.0220 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by WFDC12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WFDC12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WFDC12 | 128488 | 13 | 1 | 16 | |
| GSE20123 | WFDC12 | 128488 | 13 | 1 | 16 | |
| GSE43470 | WFDC12 | 128488 | 12 | 1 | 30 | |
| GSE46452 | WFDC12 | 128488 | 29 | 0 | 30 | |
| GSE47630 | WFDC12 | 128488 | 24 | 1 | 15 | |
| GSE54993 | WFDC12 | 128488 | 0 | 17 | 53 | |
| GSE54994 | WFDC12 | 128488 | 25 | 0 | 28 | |
| GSE60625 | WFDC12 | 128488 | 0 | 0 | 11 | |
| GSE74703 | WFDC12 | 128488 | 10 | 1 | 25 | |
| GSE74704 | WFDC12 | 128488 | 9 | 0 | 11 | |
| TCGA | WFDC12 | 128488 | 45 | 3 | 48 |
Total number of gains: 180; Total number of losses: 25; Total Number of normals: 283.
Somatic mutations of WFDC12:
Generating mutation plots.
Highly correlated genes for WFDC12:
Showing top 20/70 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WFDC12 | IL36RN | 0.639568 | 5 | 0 | 3 |
| WFDC12 | PGLYRP3 | 0.628223 | 4 | 0 | 3 |
| WFDC12 | LCE3E | 0.627409 | 4 | 0 | 3 |
| WFDC12 | LCE3D | 0.616628 | 8 | 0 | 7 |
| WFDC12 | NLRP4 | 0.61544 | 3 | 0 | 3 |
| WFDC12 | SPRR2G | 0.611642 | 6 | 0 | 5 |
| WFDC12 | KRTAP20-3 | 0.609558 | 3 | 0 | 3 |
| WFDC12 | LCE3A | 0.607778 | 4 | 0 | 3 |
| WFDC12 | SDR9C7 | 0.604106 | 5 | 0 | 4 |
| WFDC12 | KRT75 | 0.603708 | 5 | 0 | 4 |
| WFDC12 | SPRR2B | 0.596979 | 4 | 0 | 4 |
| WFDC12 | NDRG4 | 0.592234 | 4 | 0 | 3 |
| WFDC12 | CALB2 | 0.588232 | 5 | 0 | 4 |
| WFDC12 | GPR45 | 0.583719 | 4 | 0 | 3 |
| WFDC12 | SPRR2E | 0.579067 | 4 | 0 | 4 |
| WFDC12 | DUSP14 | 0.575483 | 5 | 0 | 4 |
| WFDC12 | CARD18 | 0.573558 | 5 | 0 | 4 |
| WFDC12 | PLA2G4D | 0.572744 | 4 | 0 | 3 |
| WFDC12 | SERPINB7 | 0.569774 | 6 | 0 | 4 |
| WFDC12 | SPRR2D | 0.563349 | 4 | 0 | 3 |
For details and further investigation, click here
