| Full name: pellino E3 ubiquitin protein ligase 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2p14 | ||
| Entrez ID: 57162 | HGNC ID: HGNC:8827 | Ensembl Gene: ENSG00000197329 | OMIM ID: 614797 |
| Drug and gene relationship at DGIdb | |||
Expression of PELI1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PELI1 | 57162 | 218319_at | -0.8534 | 0.1509 | |
| GSE20347 | PELI1 | 57162 | 218319_at | -1.3484 | 0.0000 | |
| GSE23400 | PELI1 | 57162 | 218319_at | -1.3313 | 0.0000 | |
| GSE26886 | PELI1 | 57162 | 218319_at | -1.3266 | 0.0000 | |
| GSE29001 | PELI1 | 57162 | 218319_at | -1.5253 | 0.0006 | |
| GSE38129 | PELI1 | 57162 | 218319_at | -0.8608 | 0.0042 | |
| GSE45670 | PELI1 | 57162 | 218319_at | -0.8289 | 0.0024 | |
| GSE53622 | PELI1 | 57162 | 3763 | -1.1433 | 0.0000 | |
| GSE53624 | PELI1 | 57162 | 3763 | -1.4886 | 0.0000 | |
| GSE63941 | PELI1 | 57162 | 218319_at | 2.2652 | 0.0059 | |
| GSE77861 | PELI1 | 57162 | 218319_at | -0.7779 | 0.1528 | |
| GSE97050 | PELI1 | 57162 | A_33_P3316928 | -0.5951 | 0.2032 | |
| SRP007169 | PELI1 | 57162 | RNAseq | -1.6948 | 0.0012 | |
| SRP008496 | PELI1 | 57162 | RNAseq | -1.7135 | 0.0000 | |
| SRP064894 | PELI1 | 57162 | RNAseq | -1.6139 | 0.0000 | |
| SRP133303 | PELI1 | 57162 | RNAseq | -0.8372 | 0.0009 | |
| SRP159526 | PELI1 | 57162 | RNAseq | -0.4699 | 0.0771 | |
| SRP193095 | PELI1 | 57162 | RNAseq | -1.6896 | 0.0000 | |
| SRP219564 | PELI1 | 57162 | RNAseq | -1.0958 | 0.0752 | |
| TCGA | PELI1 | 57162 | RNAseq | 0.0955 | 0.2230 |
Upregulated datasets: 1; Downregulated datasets: 10.
Survival by PELI1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PELI1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PELI1 | 57162 | 12 | 0 | 18 | |
| GSE20123 | PELI1 | 57162 | 12 | 0 | 18 | |
| GSE43470 | PELI1 | 57162 | 6 | 0 | 37 | |
| GSE46452 | PELI1 | 57162 | 2 | 3 | 54 | |
| GSE47630 | PELI1 | 57162 | 8 | 0 | 32 | |
| GSE54993 | PELI1 | 57162 | 0 | 6 | 64 | |
| GSE54994 | PELI1 | 57162 | 12 | 0 | 41 | |
| GSE60625 | PELI1 | 57162 | 0 | 3 | 8 | |
| GSE74703 | PELI1 | 57162 | 6 | 0 | 30 | |
| GSE74704 | PELI1 | 57162 | 10 | 0 | 10 | |
| TCGA | PELI1 | 57162 | 36 | 2 | 58 |
Total number of gains: 104; Total number of losses: 14; Total Number of normals: 370.
Somatic mutations of PELI1:
Generating mutation plots.
Highly correlated genes for PELI1:
Showing top 20/1172 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PELI1 | NUAK2 | 0.813422 | 3 | 0 | 3 |
| PELI1 | CYSRT1 | 0.802803 | 6 | 0 | 6 |
| PELI1 | DUSP5 | 0.797267 | 11 | 0 | 11 |
| PELI1 | EPGN | 0.793725 | 3 | 0 | 3 |
| PELI1 | ATG9B | 0.786505 | 7 | 0 | 7 |
| PELI1 | VSIG10L | 0.786188 | 6 | 0 | 6 |
| PELI1 | SPINK7 | 0.784071 | 6 | 0 | 6 |
| PELI1 | C18orf25 | 0.781409 | 11 | 0 | 11 |
| PELI1 | CA13 | 0.781355 | 3 | 0 | 3 |
| PELI1 | ENDOU | 0.780277 | 11 | 0 | 11 |
| PELI1 | GYS2 | 0.767261 | 10 | 0 | 10 |
| PELI1 | MPZL3 | 0.765505 | 8 | 0 | 8 |
| PELI1 | CRISP3 | 0.761815 | 11 | 0 | 11 |
| PELI1 | SLURP1 | 0.76155 | 10 | 0 | 10 |
| PELI1 | TMOD3 | 0.758897 | 11 | 0 | 11 |
| PELI1 | TGM3 | 0.758533 | 11 | 0 | 10 |
| PELI1 | SAMD5 | 0.75829 | 7 | 0 | 7 |
| PELI1 | SCEL | 0.757198 | 11 | 0 | 10 |
| PELI1 | C15orf62 | 0.756639 | 7 | 0 | 7 |
| PELI1 | ANXA9 | 0.755715 | 11 | 0 | 11 |
For details and further investigation, click here
