| Full name: NADH:ubiquinone oxidoreductase subunit B7 | Alias Symbol: B18|CI-B18|MGC2480 | ||
| Type: protein-coding gene | Cytoband: 19p13.12 | ||
| Entrez ID: 4713 | HGNC ID: HGNC:7702 | Ensembl Gene: ENSG00000099795 | OMIM ID: 603842 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of NDUFB7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NDUFB7 | 4713 | 202839_s_at | -0.4231 | 0.1511 | |
| GSE20347 | NDUFB7 | 4713 | 202839_s_at | -0.6139 | 0.0000 | |
| GSE23400 | NDUFB7 | 4713 | 202839_s_at | -0.1474 | 0.0081 | |
| GSE26886 | NDUFB7 | 4713 | 202839_s_at | 0.6647 | 0.0070 | |
| GSE29001 | NDUFB7 | 4713 | 202839_s_at | -0.3402 | 0.4236 | |
| GSE38129 | NDUFB7 | 4713 | 202839_s_at | -0.4718 | 0.0003 | |
| GSE45670 | NDUFB7 | 4713 | 202839_s_at | -0.1212 | 0.2197 | |
| GSE53622 | NDUFB7 | 4713 | 82331 | -0.2399 | 0.0004 | |
| GSE53624 | NDUFB7 | 4713 | 82331 | 0.0268 | 0.7023 | |
| GSE63941 | NDUFB7 | 4713 | 202839_s_at | 0.4735 | 0.0768 | |
| GSE77861 | NDUFB7 | 4713 | 202839_s_at | -0.1722 | 0.4308 | |
| GSE97050 | NDUFB7 | 4713 | A_23_P50872 | 0.0805 | 0.8093 | |
| SRP007169 | NDUFB7 | 4713 | RNAseq | -0.8509 | 0.0300 | |
| SRP008496 | NDUFB7 | 4713 | RNAseq | -0.6734 | 0.0042 | |
| SRP064894 | NDUFB7 | 4713 | RNAseq | 0.7385 | 0.1112 | |
| SRP133303 | NDUFB7 | 4713 | RNAseq | -0.2792 | 0.0581 | |
| SRP159526 | NDUFB7 | 4713 | RNAseq | -0.3182 | 0.1422 | |
| SRP193095 | NDUFB7 | 4713 | RNAseq | -0.6156 | 0.0000 | |
| SRP219564 | NDUFB7 | 4713 | RNAseq | -0.0983 | 0.8079 | |
| TCGA | NDUFB7 | 4713 | RNAseq | -0.0536 | 0.3408 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NDUFB7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NDUFB7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NDUFB7 | 4713 | 4 | 2 | 24 | |
| GSE20123 | NDUFB7 | 4713 | 3 | 1 | 26 | |
| GSE43470 | NDUFB7 | 4713 | 2 | 6 | 35 | |
| GSE46452 | NDUFB7 | 4713 | 47 | 1 | 11 | |
| GSE47630 | NDUFB7 | 4713 | 4 | 7 | 29 | |
| GSE54993 | NDUFB7 | 4713 | 15 | 4 | 51 | |
| GSE54994 | NDUFB7 | 4713 | 6 | 13 | 34 | |
| GSE60625 | NDUFB7 | 4713 | 9 | 0 | 2 | |
| GSE74703 | NDUFB7 | 4713 | 2 | 4 | 30 | |
| GSE74704 | NDUFB7 | 4713 | 0 | 1 | 19 | |
| TCGA | NDUFB7 | 4713 | 18 | 11 | 67 |
Total number of gains: 110; Total number of losses: 50; Total Number of normals: 328.
Somatic mutations of NDUFB7:
Generating mutation plots.
Highly correlated genes for NDUFB7:
Showing top 20/120 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NDUFB7 | MRPL54 | 0.646449 | 7 | 0 | 5 |
| NDUFB7 | CCDC124 | 0.636127 | 5 | 0 | 5 |
| NDUFB7 | NDUFS7 | 0.631785 | 6 | 0 | 5 |
| NDUFB7 | LSM10 | 0.6307 | 3 | 0 | 3 |
| NDUFB7 | TAB2 | 0.620351 | 3 | 0 | 3 |
| NDUFB7 | PET100 | 0.614214 | 4 | 0 | 3 |
| NDUFB7 | CMC4 | 0.608277 | 3 | 0 | 3 |
| NDUFB7 | UQCRC1 | 0.605608 | 10 | 0 | 7 |
| NDUFB7 | WDR83OS | 0.603695 | 11 | 0 | 7 |
| NDUFB7 | PRADC1 | 0.601935 | 5 | 0 | 4 |
| NDUFB7 | CRY1 | 0.60057 | 3 | 0 | 3 |
| NDUFB7 | UBA52 | 0.599512 | 10 | 0 | 8 |
| NDUFB7 | WBP4 | 0.596085 | 3 | 0 | 3 |
| NDUFB7 | OCEL1 | 0.594978 | 3 | 0 | 3 |
| NDUFB7 | PPP1R1A | 0.593556 | 3 | 0 | 3 |
| NDUFB7 | TOLLIP-AS1 | 0.591971 | 3 | 0 | 3 |
| NDUFB7 | PIN1 | 0.590765 | 10 | 0 | 8 |
| NDUFB7 | MRPL22 | 0.586807 | 8 | 0 | 6 |
| NDUFB7 | DCTN3 | 0.586721 | 8 | 0 | 5 |
| NDUFB7 | PEMT | 0.58668 | 4 | 0 | 3 |
For details and further investigation, click here
