CCDC124

 

Full name: coiled-coil domain containing 124 Alias Symbol: 
Type: protein-coding gene Cytoband: 19p13.11
Entrez ID: 115098 HGNC ID: HGNC:25171 Ensembl Gene: ENSG00000007080 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of CCDC124:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CCDC124 115098 225454_at 0.1156 0.8240
GSE26886 CCDC124 115098 225454_at 0.7748 0.0029
GSE45670 CCDC124 115098 225454_at 0.1495 0.3062
GSE53622 CCDC124 115098 21457 -0.1567 0.0144
GSE53624 CCDC124 115098 21457 0.0314 0.6614
GSE63941 CCDC124 115098 225454_at 1.4358 0.0005
GSE77861 CCDC124 115098 225454_at 0.2432 0.1133
GSE97050 CCDC124 115098 A_33_P3417141 -0.0083 0.9713
SRP007169 CCDC124 115098 RNAseq -0.7300 0.1118
SRP008496 CCDC124 115098 RNAseq -0.2958 0.4160
SRP064894 CCDC124 115098 RNAseq 0.2966 0.3794
SRP133303 CCDC124 115098 RNAseq 0.0764 0.6225
SRP159526 CCDC124 115098 RNAseq -0.0547 0.8447
SRP193095 CCDC124 115098 RNAseq -0.0685 0.6974
SRP219564 CCDC124 115098 RNAseq 0.0503 0.8715
TCGA CCDC124 115098 RNAseq 0.1388 0.0125

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by CCDC124 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CCDC124:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CCDC124 115098 4 4 22
GSE20123 CCDC124 115098 3 2 25
GSE43470 CCDC124 115098 2 6 35
GSE46452 CCDC124 115098 47 1 11
GSE47630 CCDC124 115098 4 8 28
GSE54993 CCDC124 115098 15 4 51
GSE54994 CCDC124 115098 6 14 33
GSE60625 CCDC124 115098 9 0 2
GSE74703 CCDC124 115098 2 4 30
GSE74704 CCDC124 115098 0 2 18
TCGA CCDC124 115098 17 9 70

Total number of gains: 109; Total number of losses: 54; Total Number of normals: 325.  

 

Somatic mutations of CCDC124:

 

Generating mutation plots.

 

Highly correlated genes for CCDC124:

 

Showing top 20/698 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CCDC124RNFT20.809659303
CCDC124USP100.782058303
CCDC124LRRC470.777633303
CCDC124CASKIN20.774591404
CCDC124CSTF2T0.770524303
CCDC124KLHDC30.766528303
CCDC124SRSF30.764426303
CCDC124CHCHD20.748716404
CCDC124NAA600.748551303
CCDC124DDIT30.748136303
CCDC124SLC25A140.744836303
CCDC124MED220.744015404
CCDC124SF10.743639303
CCDC124LSR0.740132303
CCDC124USP10.736183303
CCDC124TLN20.732407303
CCDC124TP53I130.730488303
CCDC124TFAM0.727319303
CCDC124THAP110.72698303
CCDC124SF3A20.726001303

For details and further investigation, click here