| Full name: NADH:ubiquinone oxidoreductase core subunit S7 | Alias Symbol: PSST|FLJ46880|FLJ45860|CI-20 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 374291 | HGNC ID: HGNC:7714 | Ensembl Gene: ENSG00000115286 | OMIM ID: 601825 |
| Related drugs: ME-344, METFORMIN HYDROCHLORIDE, NV-128... [more] | |||
Screen Evidence:
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Expression of NDUFS7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NDUFS7 | 374291 | 211752_s_at | -0.3489 | 0.2416 | |
| GSE20347 | NDUFS7 | 374291 | 211752_s_at | -0.8072 | 0.0000 | |
| GSE23400 | NDUFS7 | 374291 | 211752_s_at | -0.4592 | 0.0000 | |
| GSE26886 | NDUFS7 | 374291 | 211752_s_at | -0.3959 | 0.0102 | |
| GSE29001 | NDUFS7 | 374291 | 211752_s_at | -0.8463 | 0.0016 | |
| GSE38129 | NDUFS7 | 374291 | 211752_s_at | -0.5749 | 0.0001 | |
| GSE45670 | NDUFS7 | 374291 | 211752_s_at | -0.2557 | 0.0579 | |
| GSE63941 | NDUFS7 | 374291 | 211752_s_at | 0.5903 | 0.0841 | |
| GSE77861 | NDUFS7 | 374291 | 211752_s_at | -0.4038 | 0.1759 | |
| GSE97050 | NDUFS7 | 374291 | A_23_P165090 | -0.3343 | 0.2144 | |
| SRP007169 | NDUFS7 | 374291 | RNAseq | -1.5289 | 0.0000 | |
| SRP008496 | NDUFS7 | 374291 | RNAseq | -1.4888 | 0.0000 | |
| SRP064894 | NDUFS7 | 374291 | RNAseq | -0.1152 | 0.7467 | |
| SRP133303 | NDUFS7 | 374291 | RNAseq | -0.4782 | 0.0273 | |
| SRP159526 | NDUFS7 | 374291 | RNAseq | -0.4215 | 0.1836 | |
| SRP193095 | NDUFS7 | 374291 | RNAseq | -0.8339 | 0.0000 | |
| SRP219564 | NDUFS7 | 374291 | RNAseq | -0.2433 | 0.3355 | |
| TCGA | NDUFS7 | 374291 | RNAseq | -0.0858 | 0.1110 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by NDUFS7 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of NDUFS7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NDUFS7 | 374291 | 4 | 6 | 20 | |
| GSE20123 | NDUFS7 | 374291 | 4 | 5 | 21 | |
| GSE43470 | NDUFS7 | 374291 | 1 | 11 | 31 | |
| GSE46452 | NDUFS7 | 374291 | 47 | 1 | 11 | |
| GSE47630 | NDUFS7 | 374291 | 5 | 7 | 28 | |
| GSE54993 | NDUFS7 | 374291 | 13 | 4 | 53 | |
| GSE54994 | NDUFS7 | 374291 | 8 | 15 | 30 | |
| GSE60625 | NDUFS7 | 374291 | 9 | 0 | 2 | |
| GSE74703 | NDUFS7 | 374291 | 1 | 8 | 27 | |
| GSE74704 | NDUFS7 | 374291 | 3 | 3 | 14 | |
| TCGA | NDUFS7 | 374291 | 7 | 25 | 64 |
Total number of gains: 102; Total number of losses: 85; Total Number of normals: 301.
Somatic mutations of NDUFS7:
Generating mutation plots.
Highly correlated genes for NDUFS7:
Showing top 20/641 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NDUFS7 | TMEM141 | 0.778526 | 4 | 0 | 4 |
| NDUFS7 | MOB2 | 0.717474 | 3 | 0 | 3 |
| NDUFS7 | RBPJL | 0.707436 | 3 | 0 | 3 |
| NDUFS7 | MGST2 | 0.689638 | 9 | 0 | 9 |
| NDUFS7 | ABHD17A | 0.689038 | 5 | 0 | 5 |
| NDUFS7 | CLVS1 | 0.686583 | 4 | 0 | 4 |
| NDUFS7 | GLI4 | 0.684728 | 3 | 0 | 3 |
| NDUFS7 | BLOC1S1 | 0.684272 | 8 | 0 | 8 |
| NDUFS7 | SLTM | 0.673208 | 3 | 0 | 3 |
| NDUFS7 | CAPNS2 | 0.670593 | 4 | 0 | 4 |
| NDUFS7 | SMAGP | 0.661733 | 8 | 0 | 8 |
| NDUFS7 | SYTL1 | 0.658193 | 5 | 0 | 5 |
| NDUFS7 | PF4 | 0.656776 | 3 | 0 | 3 |
| NDUFS7 | CHMP2A | 0.655772 | 9 | 0 | 9 |
| NDUFS7 | HSD17B4 | 0.652383 | 7 | 0 | 7 |
| NDUFS7 | COA3 | 0.651111 | 8 | 0 | 7 |
| NDUFS7 | C1orf210 | 0.651001 | 3 | 0 | 3 |
| NDUFS7 | HS3ST6 | 0.650996 | 3 | 0 | 3 |
| NDUFS7 | SOX21-AS1 | 0.649849 | 4 | 0 | 3 |
| NDUFS7 | ZNF287 | 0.64964 | 3 | 0 | 3 |
For details and further investigation, click here
