| Full name: neuraminidase 2 | Alias Symbol: SIAL2 | ||
| Type: protein-coding gene | Cytoband: 2q37.1 | ||
| Entrez ID: 4759 | HGNC ID: HGNC:7759 | Ensembl Gene: ENSG00000115488 | OMIM ID: 605528 |
| Drug and gene relationship at DGIdb | |||
Expression of NEU2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NEU2 | 4759 | 221368_at | 0.0298 | 0.9065 | |
| GSE20347 | NEU2 | 4759 | 221368_at | -0.0399 | 0.6449 | |
| GSE23400 | NEU2 | 4759 | 221368_at | -0.0788 | 0.0011 | |
| GSE26886 | NEU2 | 4759 | 221368_at | 0.2543 | 0.0198 | |
| GSE29001 | NEU2 | 4759 | 221368_at | -0.1040 | 0.2897 | |
| GSE38129 | NEU2 | 4759 | 221368_at | -0.0612 | 0.3566 | |
| GSE45670 | NEU2 | 4759 | 221368_at | 0.0774 | 0.3913 | |
| GSE53622 | NEU2 | 4759 | 5716 | 0.6782 | 0.0006 | |
| GSE53624 | NEU2 | 4759 | 5716 | 0.3765 | 0.0097 | |
| GSE63941 | NEU2 | 4759 | 221368_at | -0.0647 | 0.7239 | |
| GSE77861 | NEU2 | 4759 | 221368_at | -0.0805 | 0.5875 | |
| TCGA | NEU2 | 4759 | RNAseq | 2.0368 | 0.0773 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NEU2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NEU2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NEU2 | 4759 | 1 | 12 | 17 | |
| GSE20123 | NEU2 | 4759 | 1 | 12 | 17 | |
| GSE43470 | NEU2 | 4759 | 1 | 9 | 33 | |
| GSE46452 | NEU2 | 4759 | 0 | 5 | 54 | |
| GSE47630 | NEU2 | 4759 | 4 | 5 | 31 | |
| GSE54993 | NEU2 | 4759 | 3 | 2 | 65 | |
| GSE54994 | NEU2 | 4759 | 6 | 10 | 37 | |
| GSE60625 | NEU2 | 4759 | 0 | 3 | 8 | |
| GSE74703 | NEU2 | 4759 | 1 | 7 | 28 | |
| GSE74704 | NEU2 | 4759 | 1 | 5 | 14 | |
| TCGA | NEU2 | 4759 | 12 | 28 | 56 |
Total number of gains: 30; Total number of losses: 98; Total Number of normals: 360.
Somatic mutations of NEU2:
Generating mutation plots.
Highly correlated genes for NEU2:
Showing top 20/270 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NEU2 | CCDC106 | 0.694777 | 3 | 0 | 3 |
| NEU2 | ZNF358 | 0.668254 | 3 | 0 | 3 |
| NEU2 | SEZ6L2 | 0.659154 | 3 | 0 | 3 |
| NEU2 | MYBPC3 | 0.655949 | 5 | 0 | 5 |
| NEU2 | FUT7 | 0.652062 | 4 | 0 | 3 |
| NEU2 | CHST8 | 0.649658 | 5 | 0 | 5 |
| NEU2 | NES | 0.640029 | 3 | 0 | 3 |
| NEU2 | NOS2 | 0.638648 | 3 | 0 | 3 |
| NEU2 | F11 | 0.633138 | 3 | 0 | 3 |
| NEU2 | VCX2 | 0.631857 | 3 | 0 | 3 |
| NEU2 | TBXA2R | 0.62951 | 4 | 0 | 4 |
| NEU2 | POU2F2 | 0.62482 | 3 | 0 | 3 |
| NEU2 | NACAD | 0.620396 | 4 | 0 | 3 |
| NEU2 | CABIN1 | 0.619971 | 3 | 0 | 3 |
| NEU2 | CNPY4 | 0.617137 | 4 | 0 | 3 |
| NEU2 | CYP2A13 | 0.611245 | 4 | 0 | 3 |
| NEU2 | ZNF366 | 0.609692 | 3 | 0 | 3 |
| NEU2 | GRIN1 | 0.607856 | 6 | 0 | 4 |
| NEU2 | CAPN10 | 0.607298 | 3 | 0 | 3 |
| NEU2 | SYDE1 | 0.607186 | 3 | 0 | 3 |
For details and further investigation, click here
