| Full name: calpain 10 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q37.3 | ||
| Entrez ID: 11132 | HGNC ID: HGNC:1477 | Ensembl Gene: ENSG00000142330 | OMIM ID: 605286 |
| Drug and gene relationship at DGIdb | |||
Expression of CAPN10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CAPN10 | 11132 | 219333_s_at | 0.1581 | 0.6601 | |
| GSE20347 | CAPN10 | 11132 | 219333_s_at | -0.2516 | 0.0077 | |
| GSE23400 | CAPN10 | 11132 | 219333_s_at | -0.2133 | 0.0000 | |
| GSE26886 | CAPN10 | 11132 | 219333_s_at | -0.0037 | 0.9848 | |
| GSE29001 | CAPN10 | 11132 | 219333_s_at | -0.3833 | 0.0062 | |
| GSE38129 | CAPN10 | 11132 | 219333_s_at | -0.3780 | 0.0014 | |
| GSE45670 | CAPN10 | 11132 | 219333_s_at | -0.1054 | 0.2540 | |
| GSE53622 | CAPN10 | 11132 | 7507 | -0.3798 | 0.0000 | |
| GSE53624 | CAPN10 | 11132 | 7507 | -0.3365 | 0.0000 | |
| GSE63941 | CAPN10 | 11132 | 219333_s_at | 0.5891 | 0.0075 | |
| GSE77861 | CAPN10 | 11132 | 219333_s_at | -0.2252 | 0.0711 | |
| GSE97050 | CAPN10 | 11132 | A_33_P3343552 | -0.2661 | 0.2556 | |
| SRP007169 | CAPN10 | 11132 | RNAseq | -1.0195 | 0.0082 | |
| SRP008496 | CAPN10 | 11132 | RNAseq | -1.0379 | 0.0003 | |
| SRP064894 | CAPN10 | 11132 | RNAseq | 0.0205 | 0.9196 | |
| SRP133303 | CAPN10 | 11132 | RNAseq | -0.3541 | 0.0614 | |
| SRP159526 | CAPN10 | 11132 | RNAseq | -0.0041 | 0.9874 | |
| SRP193095 | CAPN10 | 11132 | RNAseq | -0.0150 | 0.9085 | |
| SRP219564 | CAPN10 | 11132 | RNAseq | -0.3227 | 0.1316 | |
| TCGA | CAPN10 | 11132 | RNAseq | -0.1667 | 0.0060 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by CAPN10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CAPN10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CAPN10 | 11132 | 1 | 12 | 17 | |
| GSE20123 | CAPN10 | 11132 | 1 | 12 | 17 | |
| GSE43470 | CAPN10 | 11132 | 1 | 9 | 33 | |
| GSE46452 | CAPN10 | 11132 | 0 | 5 | 54 | |
| GSE47630 | CAPN10 | 11132 | 4 | 5 | 31 | |
| GSE54993 | CAPN10 | 11132 | 3 | 3 | 64 | |
| GSE54994 | CAPN10 | 11132 | 8 | 9 | 36 | |
| GSE60625 | CAPN10 | 11132 | 0 | 3 | 8 | |
| GSE74703 | CAPN10 | 11132 | 1 | 7 | 28 | |
| GSE74704 | CAPN10 | 11132 | 1 | 5 | 14 | |
| TCGA | CAPN10 | 11132 | 11 | 29 | 56 |
Total number of gains: 31; Total number of losses: 99; Total Number of normals: 358.
Somatic mutations of CAPN10:
Generating mutation plots.
Highly correlated genes for CAPN10:
Showing top 20/603 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CAPN10 | NOTO | 0.76626 | 3 | 0 | 3 |
| CAPN10 | PGC | 0.739192 | 3 | 0 | 3 |
| CAPN10 | DNAJB8 | 0.734105 | 3 | 0 | 3 |
| CAPN10 | ABHD11 | 0.726736 | 3 | 0 | 3 |
| CAPN10 | LRSAM1 | 0.712704 | 3 | 0 | 3 |
| CAPN10 | RNF222 | 0.706937 | 3 | 0 | 3 |
| CAPN10 | MECR | 0.699448 | 3 | 0 | 3 |
| CAPN10 | CHRNB4 | 0.698051 | 3 | 0 | 3 |
| CAPN10 | HSD3B1 | 0.689738 | 3 | 0 | 3 |
| CAPN10 | TNNT2 | 0.682734 | 4 | 0 | 3 |
| CAPN10 | PARS2 | 0.679179 | 3 | 0 | 3 |
| CAPN10 | IL17RC | 0.675701 | 9 | 0 | 7 |
| CAPN10 | TERT | 0.673548 | 6 | 0 | 6 |
| CAPN10 | ZNF335 | 0.669602 | 4 | 0 | 4 |
| CAPN10 | GCK | 0.667862 | 3 | 0 | 3 |
| CAPN10 | TULP1 | 0.665059 | 6 | 0 | 5 |
| CAPN10 | OR2H2 | 0.664655 | 6 | 0 | 5 |
| CAPN10 | RNF123 | 0.664263 | 7 | 0 | 6 |
| CAPN10 | TP73 | 0.662895 | 5 | 0 | 4 |
| CAPN10 | ASMT | 0.660608 | 3 | 0 | 3 |
For details and further investigation, click here
