| Full name: neuralized E3 ubiquitin protein ligase 3 | Alias Symbol: Lincr|LOC93082|RNF132 | ||
| Type: protein-coding gene | Cytoband: 2q11.2 | ||
| Entrez ID: 93082 | HGNC ID: HGNC:25162 | Ensembl Gene: ENSG00000163121 | OMIM ID: 617206 |
| Drug and gene relationship at DGIdb | |||
Expression of NEURL3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NEURL3 | 93082 | 232593_at | 0.0963 | 0.6684 | |
| GSE26886 | NEURL3 | 93082 | 232593_at | 0.3558 | 0.0195 | |
| GSE45670 | NEURL3 | 93082 | 232593_at | 0.3891 | 0.0281 | |
| GSE53622 | NEURL3 | 93082 | 57495 | 1.8834 | 0.0000 | |
| GSE53624 | NEURL3 | 93082 | 57495 | 2.0428 | 0.0000 | |
| GSE63941 | NEURL3 | 93082 | 232593_at | 0.5577 | 0.0924 | |
| GSE77861 | NEURL3 | 93082 | 232593_at | 0.0470 | 0.8212 | |
| SRP159526 | NEURL3 | 93082 | RNAseq | 1.7925 | 0.0061 | |
| SRP219564 | NEURL3 | 93082 | RNAseq | 3.5238 | 0.0001 | |
| TCGA | NEURL3 | 93082 | RNAseq | 3.2050 | 0.0000 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by NEURL3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NEURL3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NEURL3 | 93082 | 6 | 2 | 22 | |
| GSE20123 | NEURL3 | 93082 | 6 | 2 | 22 | |
| GSE43470 | NEURL3 | 93082 | 2 | 3 | 38 | |
| GSE46452 | NEURL3 | 93082 | 2 | 3 | 54 | |
| GSE47630 | NEURL3 | 93082 | 7 | 0 | 33 | |
| GSE54993 | NEURL3 | 93082 | 0 | 6 | 64 | |
| GSE54994 | NEURL3 | 93082 | 11 | 0 | 42 | |
| GSE60625 | NEURL3 | 93082 | 0 | 3 | 8 | |
| GSE74703 | NEURL3 | 93082 | 2 | 2 | 32 | |
| GSE74704 | NEURL3 | 93082 | 4 | 1 | 15 | |
| TCGA | NEURL3 | 93082 | 35 | 3 | 58 |
Total number of gains: 75; Total number of losses: 25; Total Number of normals: 388.
Somatic mutations of NEURL3:
Generating mutation plots.
Highly correlated genes for NEURL3:
Showing top 20/188 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NEURL3 | LINC01312 | 0.660211 | 3 | 0 | 3 |
| NEURL3 | APOE | 0.659158 | 3 | 0 | 3 |
| NEURL3 | LPIN3 | 0.633704 | 3 | 0 | 3 |
| NEURL3 | MARCKSL1 | 0.633326 | 4 | 0 | 4 |
| NEURL3 | SSR3 | 0.631274 | 4 | 0 | 3 |
| NEURL3 | CXCL1 | 0.62545 | 5 | 0 | 5 |
| NEURL3 | STX1A | 0.617302 | 3 | 0 | 3 |
| NEURL3 | CHRNA1 | 0.614143 | 3 | 0 | 3 |
| NEURL3 | CACNA1E | 0.613811 | 3 | 0 | 3 |
| NEURL3 | LIF | 0.613126 | 4 | 0 | 3 |
| NEURL3 | ACP2 | 0.613105 | 3 | 0 | 3 |
| NEURL3 | CHST11 | 0.612456 | 6 | 0 | 5 |
| NEURL3 | ICAM1 | 0.610879 | 4 | 0 | 4 |
| NEURL3 | C2orf81 | 0.603743 | 4 | 0 | 3 |
| NEURL3 | SOCS3 | 0.602476 | 3 | 0 | 3 |
| NEURL3 | SLC2A6 | 0.601036 | 4 | 0 | 3 |
| NEURL3 | LINC00161 | 0.59975 | 3 | 0 | 3 |
| NEURL3 | MST1R | 0.598719 | 4 | 0 | 3 |
| NEURL3 | NMI | 0.596461 | 3 | 0 | 3 |
| NEURL3 | SIX4 | 0.5962 | 3 | 0 | 3 |
For details and further investigation, click here
