| Full name: meteorin, glial cell differentiation regulator | Alias Symbol: MGC2601 | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 79006 | HGNC ID: HGNC:14151 | Ensembl Gene: ENSG00000103260 | OMIM ID: 610998 |
| Drug and gene relationship at DGIdb | |||
Expression of METRN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | METRN | 79006 | 232269_x_at | 0.2760 | 0.4996 | |
| GSE20347 | METRN | 79006 | 219051_x_at | 0.3500 | 0.0014 | |
| GSE23400 | METRN | 79006 | 219051_x_at | 0.1327 | 0.0703 | |
| GSE26886 | METRN | 79006 | 228419_at | -0.0313 | 0.8269 | |
| GSE29001 | METRN | 79006 | 219051_x_at | 0.2257 | 0.3149 | |
| GSE38129 | METRN | 79006 | 219051_x_at | 0.2105 | 0.3119 | |
| GSE45670 | METRN | 79006 | 232269_x_at | 0.3565 | 0.0828 | |
| GSE53622 | METRN | 79006 | 30509 | 0.3454 | 0.0005 | |
| GSE53624 | METRN | 79006 | 30509 | 0.8074 | 0.0000 | |
| GSE63941 | METRN | 79006 | 232269_x_at | -0.1837 | 0.6959 | |
| GSE77861 | METRN | 79006 | 228419_at | -0.0877 | 0.4698 | |
| GSE97050 | METRN | 79006 | A_33_P3423570 | 0.1849 | 0.6819 | |
| SRP007169 | METRN | 79006 | RNAseq | 0.0355 | 0.9466 | |
| SRP008496 | METRN | 79006 | RNAseq | 0.4817 | 0.1897 | |
| SRP064894 | METRN | 79006 | RNAseq | -0.2207 | 0.5687 | |
| SRP133303 | METRN | 79006 | RNAseq | 0.4056 | 0.0589 | |
| SRP159526 | METRN | 79006 | RNAseq | 0.3788 | 0.1946 | |
| SRP193095 | METRN | 79006 | RNAseq | 1.0762 | 0.0000 | |
| TCGA | METRN | 79006 | RNAseq | -0.1082 | 0.3880 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by METRN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of METRN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | METRN | 79006 | 5 | 5 | 20 | |
| GSE20123 | METRN | 79006 | 5 | 4 | 21 | |
| GSE43470 | METRN | 79006 | 4 | 7 | 32 | |
| GSE46452 | METRN | 79006 | 38 | 1 | 20 | |
| GSE47630 | METRN | 79006 | 13 | 6 | 21 | |
| GSE54993 | METRN | 79006 | 3 | 5 | 62 | |
| GSE54994 | METRN | 79006 | 5 | 9 | 39 | |
| GSE60625 | METRN | 79006 | 4 | 0 | 7 | |
| GSE74703 | METRN | 79006 | 4 | 5 | 27 | |
| GSE74704 | METRN | 79006 | 3 | 2 | 15 | |
| TCGA | METRN | 79006 | 20 | 15 | 61 |
Total number of gains: 104; Total number of losses: 59; Total Number of normals: 325.
Somatic mutations of METRN:
Generating mutation plots.
Highly correlated genes for METRN:
Showing top 20/186 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| METRN | REM1 | 0.701348 | 3 | 0 | 3 |
| METRN | SHANK1 | 0.686452 | 3 | 0 | 3 |
| METRN | TMEM52 | 0.676335 | 3 | 0 | 3 |
| METRN | FMNL3 | 0.638269 | 3 | 0 | 3 |
| METRN | UBASH3B | 0.638071 | 3 | 0 | 3 |
| METRN | DUSP9 | 0.624419 | 5 | 0 | 4 |
| METRN | TMEM132E | 0.622141 | 3 | 0 | 3 |
| METRN | EGLN2 | 0.621985 | 3 | 0 | 3 |
| METRN | TFE3 | 0.618739 | 3 | 0 | 3 |
| METRN | PGP | 0.613456 | 3 | 0 | 3 |
| METRN | EPHA3 | 0.61196 | 3 | 0 | 3 |
| METRN | SIVA1 | 0.610288 | 7 | 0 | 7 |
| METRN | NEUROG2 | 0.605905 | 3 | 0 | 3 |
| METRN | ZNF517 | 0.604129 | 3 | 0 | 3 |
| METRN | SNRNP25 | 0.596308 | 7 | 0 | 4 |
| METRN | RNF216 | 0.595156 | 5 | 0 | 5 |
| METRN | ATF5 | 0.593886 | 4 | 0 | 4 |
| METRN | RCAN1 | 0.59142 | 4 | 0 | 3 |
| METRN | OBSL1 | 0.590081 | 4 | 0 | 3 |
| METRN | TMEM176B | 0.585951 | 4 | 0 | 3 |
For details and further investigation, click here
