| Full name: NSFL1 cofactor | Alias Symbol: dJ776F14.1|p47|UBXD10|UBX1|UBXN2C | ||
| Type: protein-coding gene | Cytoband: 20p13 | ||
| Entrez ID: 55968 | HGNC ID: HGNC:15912 | Ensembl Gene: ENSG00000088833 | OMIM ID: 606610 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NSFL1C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NSFL1C | 55968 | 232520_s_at | 0.0355 | 0.9518 | |
| GSE20347 | NSFL1C | 55968 | 220248_x_at | -0.0117 | 0.9562 | |
| GSE23400 | NSFL1C | 55968 | 220248_x_at | 0.0539 | 0.5291 | |
| GSE26886 | NSFL1C | 55968 | 232520_s_at | -0.3677 | 0.0587 | |
| GSE29001 | NSFL1C | 55968 | 220248_x_at | -0.0137 | 0.9731 | |
| GSE38129 | NSFL1C | 55968 | 220248_x_at | 0.1431 | 0.2924 | |
| GSE45670 | NSFL1C | 55968 | 232520_s_at | 0.3208 | 0.0728 | |
| GSE53622 | NSFL1C | 55968 | 52661 | 0.1539 | 0.0358 | |
| GSE53624 | NSFL1C | 55968 | 52661 | -0.0232 | 0.7274 | |
| GSE63941 | NSFL1C | 55968 | 232520_s_at | 0.4468 | 0.2653 | |
| GSE77861 | NSFL1C | 55968 | 232520_s_at | 0.0179 | 0.9205 | |
| GSE97050 | NSFL1C | 55968 | A_24_P65864 | 0.0822 | 0.8450 | |
| SRP007169 | NSFL1C | 55968 | RNAseq | -1.2996 | 0.0005 | |
| SRP008496 | NSFL1C | 55968 | RNAseq | -0.8964 | 0.0000 | |
| SRP064894 | NSFL1C | 55968 | RNAseq | 0.0616 | 0.7542 | |
| SRP133303 | NSFL1C | 55968 | RNAseq | 0.0442 | 0.7497 | |
| SRP159526 | NSFL1C | 55968 | RNAseq | -0.0124 | 0.9323 | |
| SRP193095 | NSFL1C | 55968 | RNAseq | -0.0075 | 0.9428 | |
| SRP219564 | NSFL1C | 55968 | RNAseq | 0.1619 | 0.5761 | |
| TCGA | NSFL1C | 55968 | RNAseq | 0.0979 | 0.0528 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by NSFL1C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NSFL1C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NSFL1C | 55968 | 13 | 3 | 14 | |
| GSE20123 | NSFL1C | 55968 | 14 | 3 | 13 | |
| GSE43470 | NSFL1C | 55968 | 11 | 1 | 31 | |
| GSE46452 | NSFL1C | 55968 | 26 | 1 | 32 | |
| GSE47630 | NSFL1C | 55968 | 19 | 4 | 17 | |
| GSE54993 | NSFL1C | 55968 | 2 | 14 | 54 | |
| GSE54994 | NSFL1C | 55968 | 24 | 2 | 27 | |
| GSE60625 | NSFL1C | 55968 | 0 | 0 | 11 | |
| GSE74703 | NSFL1C | 55968 | 10 | 1 | 25 | |
| GSE74704 | NSFL1C | 55968 | 9 | 1 | 10 | |
| TCGA | NSFL1C | 55968 | 40 | 11 | 45 |
Total number of gains: 168; Total number of losses: 41; Total Number of normals: 279.
Somatic mutations of NSFL1C:
Generating mutation plots.
Highly correlated genes for NSFL1C:
Showing top 20/230 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NSFL1C | PPIP5K2 | 0.75941 | 3 | 0 | 3 |
| NSFL1C | MALT1 | 0.719216 | 3 | 0 | 3 |
| NSFL1C | RELL2 | 0.717737 | 3 | 0 | 3 |
| NSFL1C | C16orf87 | 0.713465 | 3 | 0 | 3 |
| NSFL1C | PRNP | 0.712597 | 3 | 0 | 3 |
| NSFL1C | UBXN2A | 0.712114 | 3 | 0 | 3 |
| NSFL1C | ALDH7A1 | 0.70977 | 4 | 0 | 4 |
| NSFL1C | RAD50 | 0.705298 | 3 | 0 | 3 |
| NSFL1C | ZBTB11 | 0.70029 | 3 | 0 | 3 |
| NSFL1C | SCAPER | 0.700129 | 3 | 0 | 3 |
| NSFL1C | STK35 | 0.698491 | 8 | 0 | 7 |
| NSFL1C | PDZD11 | 0.69591 | 4 | 0 | 3 |
| NSFL1C | RIOK2 | 0.691537 | 4 | 0 | 3 |
| NSFL1C | ALDH2 | 0.690177 | 3 | 0 | 3 |
| NSFL1C | ARL8B | 0.688696 | 3 | 0 | 3 |
| NSFL1C | ARPC3 | 0.685651 | 3 | 0 | 3 |
| NSFL1C | HAX1 | 0.680267 | 3 | 0 | 3 |
| NSFL1C | LYST | 0.675851 | 3 | 0 | 3 |
| NSFL1C | SLC43A3 | 0.674655 | 3 | 0 | 3 |
| NSFL1C | TRMT6 | 0.674485 | 5 | 0 | 4 |
For details and further investigation, click here
