TUBA4B

 

Full name: tubulin alpha 4b Alias Symbol: FLJ13940
Type: protein-coding gene Cytoband: 2q35
Entrez ID: 80086 HGNC ID: HGNC:18637 Ensembl Gene: ENSG00000243910 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of TUBA4B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TUBA4B 80086 207490_at 0.1723 0.7550
GSE20347 TUBA4B 80086 207490_at 0.0002 0.9989
GSE23400 TUBA4B 80086 207490_at 0.0169 0.6902
GSE26886 TUBA4B 80086 207490_at -0.0242 0.9127
GSE29001 TUBA4B 80086 207490_at -0.0641 0.7763
GSE38129 TUBA4B 80086 207490_at 0.0871 0.4113
GSE45670 TUBA4B 80086 207490_at 0.2664 0.0513
GSE63941 TUBA4B 80086 207490_at -0.0411 0.8939
GSE77861 TUBA4B 80086 207490_at 0.3238 0.2172
TCGA TUBA4B 80086 RNAseq 2.7582 0.0206

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by TUBA4B expression:

 

TCGA

 

Note: Click image to view full size file.  


Copy number change of TUBA4B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TUBA4B 80086 2 14 14
GSE20123 TUBA4B 80086 2 13 15
GSE43470 TUBA4B 80086 1 7 35
GSE46452 TUBA4B 80086 0 5 54
GSE47630 TUBA4B 80086 4 5 31
GSE54993 TUBA4B 80086 1 2 67
GSE54994 TUBA4B 80086 8 9 36
GSE60625 TUBA4B 80086 0 3 8
GSE74703 TUBA4B 80086 1 5 30
GSE74704 TUBA4B 80086 2 7 11
TCGA TUBA4B 80086 12 26 58

Total number of gains: 33; Total number of losses: 96; Total Number of normals: 359.  


 

Somatic mutations of TUBA4B:

 

Generating mutation plots.

 

Highly correlated genes for TUBA4B:

 

Showing top 20/74 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TUBA4BNIPAL40.72051303
TUBA4BTUBA4A0.709744908
TUBA4BCCDC88B0.694418303
TUBA4BTSPAN100.680414404
TUBA4BPRSS360.673947303
TUBA4BGPRIN10.668237303
TUBA4BCCM20.653092303
TUBA4BLINC004600.651732303
TUBA4BIPO40.646906303
TUBA4BIGSF80.640362303
TUBA4BSTON20.615562403
TUBA4BUCN20.605366303
TUBA4BEIF2S10.60264403
TUBA4BSH2D50.601858404
TUBA4BB3GNT90.599047303
TUBA4BPDLIM70.594456403
TUBA4BSTRN30.593182303
TUBA4BCD470.592905403
TUBA4BPMEPA10.590137403
TUBA4BFKBP30.589972303

For details and further investigation, click here