| Full name: NME/NM23 nucleoside diphosphate kinase 4 | Alias Symbol: nm23-H4|NM23H4|NDPKD | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 4833 | HGNC ID: HGNC:7852 | Ensembl Gene: ENSG00000103202 | OMIM ID: 601818 |
| Drug and gene relationship at DGIdb | |||
Expression of NME4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NME4 | 4833 | 212739_s_at | 0.0666 | 0.9466 | |
| GSE20347 | NME4 | 4833 | 212739_s_at | 0.8941 | 0.0000 | |
| GSE23400 | NME4 | 4833 | 212739_s_at | 0.3513 | 0.0047 | |
| GSE26886 | NME4 | 4833 | 212739_s_at | 1.0391 | 0.0001 | |
| GSE29001 | NME4 | 4833 | 212739_s_at | 0.3194 | 0.2603 | |
| GSE38129 | NME4 | 4833 | 212739_s_at | 0.3743 | 0.1467 | |
| GSE45670 | NME4 | 4833 | 212739_s_at | -0.1728 | 0.5784 | |
| GSE53622 | NME4 | 4833 | 15832 | 0.6367 | 0.0000 | |
| GSE53624 | NME4 | 4833 | 15832 | 0.6109 | 0.0000 | |
| GSE63941 | NME4 | 4833 | 212739_s_at | -0.8320 | 0.5042 | |
| GSE77861 | NME4 | 4833 | 212739_s_at | 0.3850 | 0.2110 | |
| GSE97050 | NME4 | 4833 | A_24_P210829 | -0.0798 | 0.8818 | |
| SRP007169 | NME4 | 4833 | RNAseq | 0.3416 | 0.5648 | |
| SRP008496 | NME4 | 4833 | RNAseq | 0.3195 | 0.3581 | |
| SRP064894 | NME4 | 4833 | RNAseq | 0.4307 | 0.2440 | |
| SRP133303 | NME4 | 4833 | RNAseq | 0.4211 | 0.0264 | |
| SRP159526 | NME4 | 4833 | RNAseq | 0.5855 | 0.0941 | |
| SRP193095 | NME4 | 4833 | RNAseq | 0.8451 | 0.0000 | |
| SRP219564 | NME4 | 4833 | RNAseq | -0.1391 | 0.8456 | |
| TCGA | NME4 | 4833 | RNAseq | 0.0245 | 0.7469 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by NME4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NME4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NME4 | 4833 | 5 | 5 | 20 | |
| GSE20123 | NME4 | 4833 | 5 | 4 | 21 | |
| GSE43470 | NME4 | 4833 | 3 | 7 | 33 | |
| GSE46452 | NME4 | 4833 | 38 | 1 | 20 | |
| GSE47630 | NME4 | 4833 | 13 | 6 | 21 | |
| GSE54993 | NME4 | 4833 | 3 | 5 | 62 | |
| GSE54994 | NME4 | 4833 | 4 | 10 | 39 | |
| GSE60625 | NME4 | 4833 | 4 | 0 | 7 | |
| GSE74703 | NME4 | 4833 | 3 | 5 | 28 | |
| GSE74704 | NME4 | 4833 | 3 | 2 | 15 | |
| TCGA | NME4 | 4833 | 20 | 15 | 61 |
Total number of gains: 101; Total number of losses: 60; Total Number of normals: 327.
Somatic mutations of NME4:
Generating mutation plots.
Highly correlated genes for NME4:
Showing top 20/1154 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NME4 | IL3RA | 0.82068 | 3 | 0 | 3 |
| NME4 | ORAI1 | 0.734822 | 3 | 0 | 3 |
| NME4 | R3HDM2 | 0.722059 | 3 | 0 | 3 |
| NME4 | RASD1 | 0.718496 | 4 | 0 | 4 |
| NME4 | ABHD1 | 0.712431 | 3 | 0 | 3 |
| NME4 | COL4A5 | 0.699793 | 8 | 0 | 7 |
| NME4 | ALG12 | 0.699211 | 3 | 0 | 3 |
| NME4 | SLC15A4 | 0.697698 | 3 | 0 | 3 |
| NME4 | RP9 | 0.696035 | 5 | 0 | 5 |
| NME4 | ARHGAP4 | 0.686143 | 3 | 0 | 3 |
| NME4 | RILPL2 | 0.686107 | 3 | 0 | 3 |
| NME4 | ANP32D | 0.680432 | 3 | 0 | 3 |
| NME4 | RPRD1A | 0.676103 | 4 | 0 | 3 |
| NME4 | PRKG2 | 0.675261 | 3 | 0 | 3 |
| NME4 | CERK | 0.675057 | 3 | 0 | 3 |
| NME4 | RAB34 | 0.673508 | 4 | 0 | 3 |
| NME4 | RPAP1 | 0.671619 | 4 | 0 | 3 |
| NME4 | SMYD5 | 0.671029 | 6 | 0 | 6 |
| NME4 | C18orf54 | 0.669662 | 4 | 0 | 4 |
| NME4 | PARM1 | 0.667154 | 3 | 0 | 3 |
For details and further investigation, click here
