| Full name: nucleolar protein 11 | Alias Symbol: DKFZP586L0724 | ||
| Type: protein-coding gene | Cytoband: 17q24.2 | ||
| Entrez ID: 25926 | HGNC ID: HGNC:24557 | Ensembl Gene: ENSG00000130935 | OMIM ID: 615366 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NOL11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NOL11 | 25926 | 221970_s_at | 0.6039 | 0.0506 | |
| GSE20347 | NOL11 | 25926 | 221970_s_at | 0.6583 | 0.0001 | |
| GSE23400 | NOL11 | 25926 | 221970_s_at | 0.7055 | 0.0000 | |
| GSE26886 | NOL11 | 25926 | 221970_s_at | 0.8684 | 0.0000 | |
| GSE29001 | NOL11 | 25926 | 221970_s_at | 0.5633 | 0.1323 | |
| GSE38129 | NOL11 | 25926 | 221970_s_at | 0.7477 | 0.0000 | |
| GSE45670 | NOL11 | 25926 | 221970_s_at | 0.4438 | 0.0081 | |
| GSE53622 | NOL11 | 25926 | 82241 | 0.6210 | 0.0000 | |
| GSE53624 | NOL11 | 25926 | 82241 | 0.6052 | 0.0000 | |
| GSE63941 | NOL11 | 25926 | 221970_s_at | 1.0584 | 0.0055 | |
| GSE77861 | NOL11 | 25926 | 221970_s_at | 0.7468 | 0.0038 | |
| GSE97050 | NOL11 | 25926 | A_23_P55073 | 0.8249 | 0.0885 | |
| SRP007169 | NOL11 | 25926 | RNAseq | 0.5819 | 0.0706 | |
| SRP008496 | NOL11 | 25926 | RNAseq | 0.6746 | 0.0022 | |
| SRP064894 | NOL11 | 25926 | RNAseq | 0.3976 | 0.0064 | |
| SRP133303 | NOL11 | 25926 | RNAseq | 0.8601 | 0.0000 | |
| SRP159526 | NOL11 | 25926 | RNAseq | 0.5082 | 0.0262 | |
| SRP193095 | NOL11 | 25926 | RNAseq | 0.0956 | 0.3949 | |
| SRP219564 | NOL11 | 25926 | RNAseq | 0.4844 | 0.1797 | |
| TCGA | NOL11 | 25926 | RNAseq | 0.2321 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by NOL11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NOL11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NOL11 | 25926 | 3 | 2 | 25 | |
| GSE20123 | NOL11 | 25926 | 3 | 2 | 25 | |
| GSE43470 | NOL11 | 25926 | 4 | 0 | 39 | |
| GSE46452 | NOL11 | 25926 | 31 | 1 | 27 | |
| GSE47630 | NOL11 | 25926 | 7 | 1 | 32 | |
| GSE54993 | NOL11 | 25926 | 2 | 5 | 63 | |
| GSE54994 | NOL11 | 25926 | 9 | 4 | 40 | |
| GSE60625 | NOL11 | 25926 | 4 | 2 | 5 | |
| GSE74703 | NOL11 | 25926 | 4 | 0 | 32 | |
| GSE74704 | NOL11 | 25926 | 3 | 1 | 16 | |
| TCGA | NOL11 | 25926 | 28 | 8 | 60 |
Total number of gains: 98; Total number of losses: 26; Total Number of normals: 364.
Somatic mutations of NOL11:
Generating mutation plots.
Highly correlated genes for NOL11:
Showing top 20/2041 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NOL11 | LRRCC1 | 0.799489 | 3 | 0 | 3 |
| NOL11 | CCT5 | 0.784754 | 8 | 0 | 8 |
| NOL11 | PSMD12 | 0.772453 | 11 | 0 | 11 |
| NOL11 | NMT1 | 0.765846 | 12 | 0 | 11 |
| NOL11 | MCM6 | 0.754249 | 13 | 0 | 13 |
| NOL11 | RAD18 | 0.753663 | 3 | 0 | 3 |
| NOL11 | LRRC59 | 0.752647 | 9 | 0 | 9 |
| NOL11 | ACLY | 0.752156 | 10 | 0 | 9 |
| NOL11 | TTC8 | 0.750851 | 3 | 0 | 3 |
| NOL11 | RFC2 | 0.750472 | 11 | 0 | 11 |
| NOL11 | SNRPG | 0.748063 | 12 | 0 | 12 |
| NOL11 | C15orf61 | 0.745469 | 4 | 0 | 4 |
| NOL11 | U2SURP | 0.744399 | 10 | 0 | 10 |
| NOL11 | PRKDC | 0.744362 | 11 | 0 | 11 |
| NOL11 | RUVBL1 | 0.743088 | 12 | 0 | 12 |
| NOL11 | STIP1 | 0.74181 | 10 | 0 | 10 |
| NOL11 | MRPL42 | 0.740282 | 10 | 0 | 8 |
| NOL11 | PUS7 | 0.738643 | 11 | 0 | 10 |
| NOL11 | USP42 | 0.738621 | 5 | 0 | 5 |
| NOL11 | ECT2 | 0.736395 | 12 | 0 | 12 |
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