PTRH2

 

Full name: peptidyl-tRNA hydrolase 2 Alias Symbol: BIT1|CGI-147|PTH2|CFAP37
Type: protein-coding gene Cytoband: 17q23.1
Entrez ID: 51651 HGNC ID: HGNC:24265 Ensembl Gene: ENSG00000141378 OMIM ID: 608625
Drug and gene relationship at DGIdb

 

Expression of PTRH2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PTRH2 51651 218732_at 0.7990 0.0339
GSE20347 PTRH2 51651 218732_at 0.7513 0.0001
GSE23400 PTRH2 51651 218732_at 0.5250 0.0000
GSE26886 PTRH2 51651 218732_at 0.9901 0.0000
GSE29001 PTRH2 51651 218732_at 0.6540 0.0065
GSE38129 PTRH2 51651 218732_at 0.8008 0.0000
GSE45670 PTRH2 51651 218732_at 0.6885 0.0009
GSE53622 PTRH2 51651 48531 0.7805 0.0000
GSE53624 PTRH2 51651 48531 0.9931 0.0000
GSE63941 PTRH2 51651 218732_at 0.2579 0.5336
GSE77861 PTRH2 51651 218732_at 0.5990 0.0023
GSE97050 PTRH2 51651 A_23_P15493 0.7175 0.1725
SRP007169 PTRH2 51651 RNAseq 0.7520 0.0858
SRP008496 PTRH2 51651 RNAseq 0.7962 0.0098
SRP064894 PTRH2 51651 RNAseq 0.8203 0.0010
SRP133303 PTRH2 51651 RNAseq 0.6591 0.0066
SRP159526 PTRH2 51651 RNAseq 0.7389 0.0067
SRP193095 PTRH2 51651 RNAseq 0.2186 0.1088
SRP219564 PTRH2 51651 RNAseq 0.1592 0.6061
TCGA PTRH2 51651 RNAseq 0.2844 0.0000

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by PTRH2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of PTRH2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PTRH2 51651 6 1 23
GSE20123 PTRH2 51651 6 1 23
GSE43470 PTRH2 51651 5 0 38
GSE46452 PTRH2 51651 32 0 27
GSE47630 PTRH2 51651 7 1 32
GSE54993 PTRH2 51651 2 5 63
GSE54994 PTRH2 51651 9 5 39
GSE60625 PTRH2 51651 4 0 7
GSE74703 PTRH2 51651 5 0 31
GSE74704 PTRH2 51651 5 1 14
TCGA PTRH2 51651 27 8 61

Total number of gains: 108; Total number of losses: 22; Total Number of normals: 358.  

 

Somatic mutations of PTRH2:

 

Generating mutation plots.

 

Highly correlated genes for PTRH2:

 

Showing top 20/2207 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PTRH2NIFK0.798239707
PTRH2BOLA30.786717707
PTRH2PYCR20.781837303
PTRH2DNAJB110.781717606
PTRH2MTBP0.77427505
PTRH2FAM89A0.769732303
PTRH2FEN10.766096808
PTRH2CTU20.764287606
PTRH2FMNL20.763426707
PTRH2ACLY0.75928811011
PTRH2EME10.758497505
PTRH2XPR10.758176707
PTRH2MRGBP0.7519110010
PTRH2CENPN0.74785711011
PTRH2LHX50.747539404
PTRH2NOP560.747074303
PTRH2IMP40.74249411010
PTRH2NOP20.74234812011
PTRH2SCYL10.741329505
PTRH2C11orf240.73696111010

For details and further investigation, click here