| Full name: secernin 1 | Alias Symbol: KIAA0193 | ||
| Type: protein-coding gene | Cytoband: 7p14.3 | ||
| Entrez ID: 9805 | HGNC ID: HGNC:22192 | Ensembl Gene: ENSG00000136193 | OMIM ID: 614965 |
| Drug and gene relationship at DGIdb | |||
Expression of SCRN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SCRN1 | 9805 | 201462_at | 0.5483 | 0.5645 | |
| GSE20347 | SCRN1 | 9805 | 201462_at | 1.1261 | 0.0000 | |
| GSE23400 | SCRN1 | 9805 | 201462_at | 0.6168 | 0.0000 | |
| GSE26886 | SCRN1 | 9805 | 201462_at | 0.8322 | 0.0014 | |
| GSE29001 | SCRN1 | 9805 | 201462_at | 1.1026 | 0.0050 | |
| GSE38129 | SCRN1 | 9805 | 201462_at | 0.6263 | 0.0047 | |
| GSE45670 | SCRN1 | 9805 | 201462_at | 0.5222 | 0.0408 | |
| GSE53622 | SCRN1 | 9805 | 46076 | 0.5552 | 0.0000 | |
| GSE53624 | SCRN1 | 9805 | 46076 | 0.7727 | 0.0000 | |
| GSE63941 | SCRN1 | 9805 | 201462_at | -0.9442 | 0.1836 | |
| GSE77861 | SCRN1 | 9805 | 201462_at | 1.9166 | 0.0003 | |
| GSE97050 | SCRN1 | 9805 | A_23_P366366 | -0.0703 | 0.8548 | |
| SRP007169 | SCRN1 | 9805 | RNAseq | 1.4174 | 0.0002 | |
| SRP008496 | SCRN1 | 9805 | RNAseq | 1.7522 | 0.0000 | |
| SRP064894 | SCRN1 | 9805 | RNAseq | 0.8045 | 0.0000 | |
| SRP133303 | SCRN1 | 9805 | RNAseq | 0.8591 | 0.0004 | |
| SRP159526 | SCRN1 | 9805 | RNAseq | 0.7709 | 0.0000 | |
| SRP193095 | SCRN1 | 9805 | RNAseq | 1.2521 | 0.0000 | |
| SRP219564 | SCRN1 | 9805 | RNAseq | -0.0622 | 0.9165 | |
| TCGA | SCRN1 | 9805 | RNAseq | 0.0127 | 0.8589 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by SCRN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SCRN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SCRN1 | 9805 | 16 | 0 | 14 | |
| GSE20123 | SCRN1 | 9805 | 16 | 0 | 14 | |
| GSE43470 | SCRN1 | 9805 | 4 | 0 | 39 | |
| GSE46452 | SCRN1 | 9805 | 11 | 1 | 47 | |
| GSE47630 | SCRN1 | 9805 | 8 | 1 | 31 | |
| GSE54993 | SCRN1 | 9805 | 0 | 6 | 64 | |
| GSE54994 | SCRN1 | 9805 | 19 | 3 | 31 | |
| GSE60625 | SCRN1 | 9805 | 0 | 0 | 11 | |
| GSE74703 | SCRN1 | 9805 | 4 | 0 | 32 | |
| GSE74704 | SCRN1 | 9805 | 10 | 0 | 10 | |
| TCGA | SCRN1 | 9805 | 55 | 6 | 35 |
Total number of gains: 143; Total number of losses: 17; Total Number of normals: 328.
Somatic mutations of SCRN1:
Generating mutation plots.
Highly correlated genes for SCRN1:
Showing top 20/1403 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SCRN1 | WDR81 | 0.795747 | 3 | 0 | 3 |
| SCRN1 | NOM1 | 0.780202 | 3 | 0 | 3 |
| SCRN1 | RAVER1 | 0.756951 | 3 | 0 | 3 |
| SCRN1 | GATAD2B | 0.756834 | 3 | 0 | 3 |
| SCRN1 | CPT1A | 0.750145 | 4 | 0 | 4 |
| SCRN1 | JAK1 | 0.749716 | 3 | 0 | 3 |
| SCRN1 | SH3RF3 | 0.749005 | 3 | 0 | 3 |
| SCRN1 | TRIM35 | 0.748524 | 3 | 0 | 3 |
| SCRN1 | SDHAF2 | 0.747045 | 3 | 0 | 3 |
| SCRN1 | PPP1R21 | 0.737597 | 3 | 0 | 3 |
| SCRN1 | KRTCAP2 | 0.7297 | 4 | 0 | 4 |
| SCRN1 | UBQLN4 | 0.729083 | 3 | 0 | 3 |
| SCRN1 | RAB34 | 0.725263 | 3 | 0 | 3 |
| SCRN1 | PPTC7 | 0.723663 | 4 | 0 | 3 |
| SCRN1 | CRTC2 | 0.723053 | 4 | 0 | 3 |
| SCRN1 | NUP205 | 0.722806 | 4 | 0 | 4 |
| SCRN1 | ALKBH6 | 0.719958 | 4 | 0 | 4 |
| SCRN1 | CHST15 | 0.718262 | 11 | 0 | 11 |
| SCRN1 | C20orf194 | 0.717501 | 4 | 0 | 3 |
| SCRN1 | PTGFRN | 0.714673 | 7 | 0 | 6 |
For details and further investigation, click here
