| Full name: glutathione S-transferase mu 2 | Alias Symbol: GST4 | ||
| Type: protein-coding gene | Cytoband: 1p13.3 | ||
| Entrez ID: 2946 | HGNC ID: HGNC:4634 | Ensembl Gene: ENSG00000213366 | OMIM ID: 138380 |
| Drug and gene relationship at DGIdb | |||
Expression of GSTM2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GSTM2 | 2946 | 204418_x_at | 0.1120 | 0.9245 | |
| GSE20347 | GSTM2 | 2946 | 204418_x_at | 0.3786 | 0.4207 | |
| GSE23400 | GSTM2 | 2946 | 204418_x_at | 0.1714 | 0.4766 | |
| GSE26886 | GSTM2 | 2946 | 204418_x_at | 0.0634 | 0.9363 | |
| GSE29001 | GSTM2 | 2946 | 204418_x_at | -0.1197 | 0.8276 | |
| GSE38129 | GSTM2 | 2946 | 204418_x_at | 0.3182 | 0.3617 | |
| GSE45670 | GSTM2 | 2946 | 204418_x_at | -0.7972 | 0.0905 | |
| GSE53622 | GSTM2 | 2946 | 59151 | -0.3051 | 0.1295 | |
| GSE53624 | GSTM2 | 2946 | 59151 | -0.2387 | 0.0994 | |
| GSE63941 | GSTM2 | 2946 | 204418_x_at | -0.2108 | 0.8887 | |
| GSE77861 | GSTM2 | 2946 | 204418_x_at | -0.0990 | 0.9417 | |
| GSE97050 | GSTM2 | 2946 | A_33_P3410351 | -0.7293 | 0.2422 | |
| SRP007169 | GSTM2 | 2946 | RNAseq | 2.2955 | 0.0021 | |
| SRP008496 | GSTM2 | 2946 | RNAseq | 1.9482 | 0.0036 | |
| SRP064894 | GSTM2 | 2946 | RNAseq | -0.7220 | 0.0387 | |
| SRP133303 | GSTM2 | 2946 | RNAseq | -1.1475 | 0.0000 | |
| SRP159526 | GSTM2 | 2946 | RNAseq | 1.9491 | 0.0035 | |
| SRP193095 | GSTM2 | 2946 | RNAseq | 1.1724 | 0.0013 | |
| SRP219564 | GSTM2 | 2946 | RNAseq | -1.4114 | 0.0195 | |
| TCGA | GSTM2 | 2946 | RNAseq | -0.0742 | 0.7830 |
Upregulated datasets: 4; Downregulated datasets: 2.
Survival by GSTM2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GSTM2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GSTM2 | 2946 | 0 | 12 | 18 | |
| GSE20123 | GSTM2 | 2946 | 0 | 11 | 19 | |
| GSE43470 | GSTM2 | 2946 | 0 | 9 | 34 | |
| GSE46452 | GSTM2 | 2946 | 2 | 1 | 56 | |
| GSE47630 | GSTM2 | 2946 | 9 | 5 | 26 | |
| GSE54993 | GSTM2 | 2946 | 0 | 1 | 69 | |
| GSE54994 | GSTM2 | 2946 | 7 | 4 | 42 | |
| GSE60625 | GSTM2 | 2946 | 0 | 0 | 11 | |
| GSE74703 | GSTM2 | 2946 | 0 | 7 | 29 | |
| GSE74704 | GSTM2 | 2946 | 0 | 7 | 13 | |
| TCGA | GSTM2 | 2946 | 9 | 26 | 61 |
Total number of gains: 27; Total number of losses: 83; Total Number of normals: 378.
Somatic mutations of GSTM2:
Generating mutation plots.
Highly correlated genes for GSTM2:
Showing top 20/61 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GSTM2 | GSTM1 | 0.948241 | 13 | 0 | 13 |
| GSTM2 | NPTXR | 0.703521 | 3 | 0 | 3 |
| GSTM2 | GSTM3 | 0.692392 | 12 | 0 | 12 |
| GSTM2 | HOXB4 | 0.673489 | 3 | 0 | 3 |
| GSTM2 | KY | 0.667017 | 3 | 0 | 3 |
| GSTM2 | GSTM4 | 0.659605 | 13 | 0 | 13 |
| GSTM2 | ARHGAP1 | 0.657704 | 3 | 0 | 3 |
| GSTM2 | JPH3 | 0.657688 | 3 | 0 | 3 |
| GSTM2 | IL3RA | 0.656832 | 3 | 0 | 3 |
| GSTM2 | ADPRH | 0.640715 | 3 | 0 | 3 |
| GSTM2 | CDKL5 | 0.635599 | 3 | 0 | 3 |
| GSTM2 | NHSL2 | 0.627927 | 3 | 0 | 3 |
| GSTM2 | SYNGR1 | 0.625815 | 3 | 0 | 3 |
| GSTM2 | ZER1 | 0.61396 | 4 | 0 | 3 |
| GSTM2 | HS1BP3 | 0.610294 | 3 | 0 | 3 |
| GSTM2 | REM1 | 0.604079 | 4 | 0 | 3 |
| GSTM2 | TSPAN7 | 0.598524 | 13 | 0 | 11 |
| GSTM2 | MATN4 | 0.596461 | 3 | 0 | 3 |
| GSTM2 | LRRTM1 | 0.5927 | 3 | 0 | 3 |
| GSTM2 | TBC1D17 | 0.589605 | 4 | 0 | 3 |
For details and further investigation, click here
