OPCML

 

Full name: opioid binding protein/cell adhesion molecule like Alias Symbol: OPCM|OBCAM|IGLON1
Type: protein-coding gene Cytoband: 11q25
Entrez ID: 4978 HGNC ID: HGNC:8143 Ensembl Gene: ENSG00000183715 OMIM ID: 600632
Drug and gene relationship at DGIdb

 

Expression of OPCML:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 OPCML 4978 206215_at 0.0050 0.9911
GSE20347 OPCML 4978 206215_at 0.0485 0.6656
GSE23400 OPCML 4978 206215_at -0.1960 0.0000
GSE26886 OPCML 4978 206215_at -0.0468 0.6918
GSE29001 OPCML 4978 206215_at -0.1734 0.2926
GSE38129 OPCML 4978 206215_at -0.2085 0.0297
GSE45670 OPCML 4978 206215_at 0.0119 0.9308
GSE53622 OPCML 4978 53407 -0.5921 0.0003
GSE53624 OPCML 4978 53407 -0.8154 0.0000
GSE63941 OPCML 4978 206215_at -0.0239 0.9076
GSE77861 OPCML 4978 214111_at -0.1464 0.1157
SRP133303 OPCML 4978 RNAseq -1.5024 0.0047
TCGA OPCML 4978 RNAseq -2.0606 0.0002

Upregulated datasets: 0; Downregulated datasets: 2.  


 

Survival by OPCML expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of OPCML:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 OPCML 4978 0 15 15
GSE20123 OPCML 4978 0 15 15
GSE43470 OPCML 4978 3 8 32
GSE46452 OPCML 4978 3 26 30
GSE47630 OPCML 4978 2 19 19
GSE54993 OPCML 4978 10 0 60
GSE54994 OPCML 4978 5 19 29
GSE60625 OPCML 4978 0 3 8
GSE74703 OPCML 4978 2 5 29
GSE74704 OPCML 4978 0 11 9
TCGA OPCML 4978 7 49 40

Total number of gains: 32; Total number of losses: 170; Total Number of normals: 286.  


 

Somatic mutations of OPCML:

 

Generating mutation plots.

 

Highly correlated genes for OPCML:

 

Showing top 20/569 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
OPCMLSST0.715402303
OPCMLMUC5AC0.695457404
OPCMLCD79A0.691411303
OPCMLPHLDB10.680261404
OPCMLCHST80.677555303
OPCMLDCSTAMP0.677257303
OPCMLPSG10.672276404
OPCMLNR6A10.670143404
OPCMLTREML20.660829504
OPCMLSGK20.659885606
OPCMLRCVRN0.655903504
OPCMLPRAMEF100.654927303
OPCMLPRAMEF110.652265504
OPCMLCAMK2B0.651369605
OPCMLDMBT10.649667404
OPCMLFSHR0.645453403
OPCMLPTGER10.644063303
OPCMLKRTAP5-90.644039404
OPCMLSLC5A50.643613504
OPCMLMYO1A0.643211606

For details and further investigation, click here