| Full name: nuclear receptor binding protein 1 | Alias Symbol: BCON3|MUDPNP|MADM | ||
| Type: protein-coding gene | Cytoband: 2p23.3 | ||
| Entrez ID: 29959 | HGNC ID: HGNC:7993 | Ensembl Gene: ENSG00000115216 | OMIM ID: 606010 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of NRBP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NRBP1 | 29959 | 217765_at | -0.0979 | 0.8544 | |
| GSE20347 | NRBP1 | 29959 | 217765_at | -0.4704 | 0.0045 | |
| GSE23400 | NRBP1 | 29959 | 217765_at | -0.3707 | 0.0000 | |
| GSE26886 | NRBP1 | 29959 | 217765_at | -0.8671 | 0.0000 | |
| GSE29001 | NRBP1 | 29959 | 217765_at | -0.5974 | 0.0323 | |
| GSE38129 | NRBP1 | 29959 | 217765_at | -0.2137 | 0.1494 | |
| GSE45670 | NRBP1 | 29959 | 217765_at | 0.1730 | 0.2032 | |
| GSE53622 | NRBP1 | 29959 | 97636 | -0.3897 | 0.0000 | |
| GSE53624 | NRBP1 | 29959 | 97636 | -0.5043 | 0.0000 | |
| GSE63941 | NRBP1 | 29959 | 217765_at | 0.5582 | 0.1018 | |
| GSE77861 | NRBP1 | 29959 | 217765_at | -0.2052 | 0.0830 | |
| GSE97050 | NRBP1 | 29959 | A_23_P165442 | 0.0180 | 0.9544 | |
| SRP007169 | NRBP1 | 29959 | RNAseq | -1.5602 | 0.0000 | |
| SRP008496 | NRBP1 | 29959 | RNAseq | -1.3300 | 0.0000 | |
| SRP064894 | NRBP1 | 29959 | RNAseq | -0.5078 | 0.0008 | |
| SRP133303 | NRBP1 | 29959 | RNAseq | -0.3184 | 0.0328 | |
| SRP159526 | NRBP1 | 29959 | RNAseq | -0.4973 | 0.1002 | |
| SRP193095 | NRBP1 | 29959 | RNAseq | -0.4664 | 0.0021 | |
| SRP219564 | NRBP1 | 29959 | RNAseq | -0.6634 | 0.0513 | |
| TCGA | NRBP1 | 29959 | RNAseq | 0.1396 | 0.0018 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by NRBP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NRBP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NRBP1 | 29959 | 11 | 2 | 17 | |
| GSE20123 | NRBP1 | 29959 | 11 | 2 | 17 | |
| GSE43470 | NRBP1 | 29959 | 3 | 1 | 39 | |
| GSE46452 | NRBP1 | 29959 | 2 | 4 | 53 | |
| GSE47630 | NRBP1 | 29959 | 8 | 0 | 32 | |
| GSE54993 | NRBP1 | 29959 | 0 | 6 | 64 | |
| GSE54994 | NRBP1 | 29959 | 10 | 0 | 43 | |
| GSE60625 | NRBP1 | 29959 | 0 | 3 | 8 | |
| GSE74703 | NRBP1 | 29959 | 3 | 0 | 33 | |
| GSE74704 | NRBP1 | 29959 | 9 | 1 | 10 | |
| TCGA | NRBP1 | 29959 | 36 | 2 | 58 |
Total number of gains: 93; Total number of losses: 21; Total Number of normals: 374.
Somatic mutations of NRBP1:
Generating mutation plots.
Highly correlated genes for NRBP1:
Showing top 20/844 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NRBP1 | LRRC28 | 0.753591 | 3 | 0 | 3 |
| NRBP1 | CNFN | 0.702934 | 5 | 0 | 5 |
| NRBP1 | MOV10L1 | 0.702419 | 3 | 0 | 3 |
| NRBP1 | GID8 | 0.700359 | 6 | 0 | 6 |
| NRBP1 | ANKRD22 | 0.692114 | 3 | 0 | 3 |
| NRBP1 | PCBP1-AS1 | 0.686754 | 3 | 0 | 3 |
| NRBP1 | EPGN | 0.683752 | 3 | 0 | 3 |
| NRBP1 | GBP6 | 0.680522 | 3 | 0 | 3 |
| NRBP1 | ARCN1 | 0.679545 | 3 | 0 | 3 |
| NRBP1 | RARG | 0.679401 | 8 | 0 | 7 |
| NRBP1 | NHLRC4 | 0.67374 | 3 | 0 | 3 |
| NRBP1 | TMEM79 | 0.673518 | 6 | 0 | 6 |
| NRBP1 | SPNS2 | 0.673037 | 4 | 0 | 4 |
| NRBP1 | IQCF1 | 0.672539 | 4 | 0 | 4 |
| NRBP1 | ORMDL2 | 0.669406 | 8 | 0 | 8 |
| NRBP1 | PRSS27 | 0.668217 | 5 | 0 | 4 |
| NRBP1 | SPINK7 | 0.666888 | 5 | 0 | 5 |
| NRBP1 | VSIG10L | 0.664566 | 5 | 0 | 4 |
| NRBP1 | CYSRT1 | 0.661501 | 5 | 0 | 4 |
| NRBP1 | UPK3B | 0.661426 | 3 | 0 | 3 |
For details and further investigation, click here
