| Full name: ankyrin repeat domain 22 | Alias Symbol: MGC22805 | ||
| Type: protein-coding gene | Cytoband: 10q23.31 | ||
| Entrez ID: 118932 | HGNC ID: HGNC:28321 | Ensembl Gene: ENSG00000152766 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ANKRD22:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANKRD22 | 118932 | 238439_at | -1.0297 | 0.3859 | |
| GSE26886 | ANKRD22 | 118932 | 238439_at | -3.4574 | 0.0000 | |
| GSE45670 | ANKRD22 | 118932 | 238439_at | -0.3672 | 0.2580 | |
| GSE63941 | ANKRD22 | 118932 | 239196_at | 1.5134 | 0.1229 | |
| GSE77861 | ANKRD22 | 118932 | 239196_at | -0.9735 | 0.0057 | |
| GSE97050 | ANKRD22 | 118932 | A_33_P3407880 | -0.1422 | 0.5982 | |
| SRP007169 | ANKRD22 | 118932 | RNAseq | -2.9498 | 0.0000 | |
| SRP008496 | ANKRD22 | 118932 | RNAseq | -2.9524 | 0.0000 | |
| SRP064894 | ANKRD22 | 118932 | RNAseq | -2.2789 | 0.0000 | |
| SRP133303 | ANKRD22 | 118932 | RNAseq | -1.4669 | 0.0000 | |
| SRP159526 | ANKRD22 | 118932 | RNAseq | -2.5324 | 0.0000 | |
| SRP193095 | ANKRD22 | 118932 | RNAseq | -1.9242 | 0.0000 | |
| SRP219564 | ANKRD22 | 118932 | RNAseq | -2.1554 | 0.0232 | |
| TCGA | ANKRD22 | 118932 | RNAseq | -0.5431 | 0.0044 |
Upregulated datasets: 0; Downregulated datasets: 8.
Survival by ANKRD22 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ANKRD22:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANKRD22 | 118932 | 2 | 7 | 21 | |
| GSE20123 | ANKRD22 | 118932 | 2 | 6 | 22 | |
| GSE43470 | ANKRD22 | 118932 | 0 | 8 | 35 | |
| GSE46452 | ANKRD22 | 118932 | 0 | 11 | 48 | |
| GSE47630 | ANKRD22 | 118932 | 2 | 14 | 24 | |
| GSE54993 | ANKRD22 | 118932 | 7 | 0 | 63 | |
| GSE54994 | ANKRD22 | 118932 | 1 | 11 | 41 | |
| GSE60625 | ANKRD22 | 118932 | 0 | 0 | 11 | |
| GSE74703 | ANKRD22 | 118932 | 0 | 6 | 30 | |
| GSE74704 | ANKRD22 | 118932 | 1 | 4 | 15 | |
| TCGA | ANKRD22 | 118932 | 7 | 27 | 62 |
Total number of gains: 22; Total number of losses: 94; Total Number of normals: 372.
Somatic mutations of ANKRD22:
Generating mutation plots.
Highly correlated genes for ANKRD22:
Showing top 20/1002 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANKRD22 | KALRN | 0.809774 | 4 | 0 | 4 |
| ANKRD22 | MPZL3 | 0.801692 | 6 | 0 | 6 |
| ANKRD22 | SLC35C1 | 0.791202 | 4 | 0 | 4 |
| ANKRD22 | CAPN14 | 0.787677 | 4 | 0 | 4 |
| ANKRD22 | CLINT1 | 0.787614 | 4 | 0 | 4 |
| ANKRD22 | TTC9 | 0.787363 | 5 | 0 | 5 |
| ANKRD22 | TMED3 | 0.784432 | 4 | 0 | 4 |
| ANKRD22 | EPB41L3 | 0.783316 | 4 | 0 | 4 |
| ANKRD22 | TGM1 | 0.782274 | 6 | 0 | 6 |
| ANKRD22 | GALNT5 | 0.781901 | 3 | 0 | 3 |
| ANKRD22 | DGAT2 | 0.777639 | 3 | 0 | 3 |
| ANKRD22 | RAB10 | 0.777008 | 5 | 0 | 4 |
| ANKRD22 | GRPEL2 | 0.775333 | 5 | 0 | 5 |
| ANKRD22 | CLIC3 | 0.774688 | 6 | 0 | 6 |
| ANKRD22 | GLTP | 0.771445 | 6 | 0 | 6 |
| ANKRD22 | CNFN | 0.769653 | 6 | 0 | 6 |
| ANKRD22 | SFTA2 | 0.769266 | 4 | 0 | 4 |
| ANKRD22 | LPIN1 | 0.769059 | 4 | 0 | 4 |
| ANKRD22 | C12orf74 | 0.767577 | 3 | 0 | 3 |
| ANKRD22 | C5orf66-AS1 | 0.766869 | 4 | 0 | 4 |
For details and further investigation, click here
