| Full name: Mov10 like RISC complex RNA helicase 1 | Alias Symbol: DJ402G11.8|DKFZp434B0717|CHAMP | ||
| Type: protein-coding gene | Cytoband: 22q13.33 | ||
| Entrez ID: 54456 | HGNC ID: HGNC:7201 | Ensembl Gene: ENSG00000073146 | OMIM ID: 605794 |
| Drug and gene relationship at DGIdb | |||
Expression of MOV10L1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MOV10L1 | 54456 | 239257_at | 0.0910 | 0.6166 | |
| GSE26886 | MOV10L1 | 54456 | 239257_at | 0.0266 | 0.8354 | |
| GSE45670 | MOV10L1 | 54456 | 239257_at | 0.0601 | 0.5545 | |
| GSE53622 | MOV10L1 | 54456 | 71790 | -2.1565 | 0.0000 | |
| GSE53624 | MOV10L1 | 54456 | 71790 | -2.2653 | 0.0000 | |
| GSE63941 | MOV10L1 | 54456 | 239257_at | -0.4117 | 0.1759 | |
| GSE77861 | MOV10L1 | 54456 | 239257_at | -0.3405 | 0.0203 | |
| SRP133303 | MOV10L1 | 54456 | RNAseq | 1.9789 | 0.0000 | |
| SRP159526 | MOV10L1 | 54456 | RNAseq | 2.1327 | 0.0016 | |
| TCGA | MOV10L1 | 54456 | RNAseq | 2.8896 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 2.
Survival by MOV10L1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MOV10L1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MOV10L1 | 54456 | 3 | 8 | 19 | |
| GSE20123 | MOV10L1 | 54456 | 3 | 8 | 19 | |
| GSE43470 | MOV10L1 | 54456 | 2 | 8 | 33 | |
| GSE46452 | MOV10L1 | 54456 | 31 | 2 | 26 | |
| GSE47630 | MOV10L1 | 54456 | 9 | 4 | 27 | |
| GSE54993 | MOV10L1 | 54456 | 4 | 6 | 60 | |
| GSE54994 | MOV10L1 | 54456 | 11 | 8 | 34 | |
| GSE60625 | MOV10L1 | 54456 | 5 | 0 | 6 | |
| GSE74703 | MOV10L1 | 54456 | 2 | 6 | 28 | |
| GSE74704 | MOV10L1 | 54456 | 1 | 4 | 15 | |
| TCGA | MOV10L1 | 54456 | 26 | 16 | 54 |
Total number of gains: 97; Total number of losses: 70; Total Number of normals: 321.
Somatic mutations of MOV10L1:
Generating mutation plots.
Highly correlated genes for MOV10L1:
Showing top 20/347 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MOV10L1 | EPS8L2 | 0.830354 | 3 | 0 | 3 |
| MOV10L1 | EVPL | 0.794852 | 3 | 0 | 3 |
| MOV10L1 | C6orf132 | 0.785075 | 3 | 0 | 3 |
| MOV10L1 | ANO10 | 0.775961 | 3 | 0 | 3 |
| MOV10L1 | ARHGEF10L | 0.775549 | 3 | 0 | 3 |
| MOV10L1 | MALL | 0.771005 | 3 | 0 | 3 |
| MOV10L1 | DUOX1 | 0.766355 | 3 | 0 | 3 |
| MOV10L1 | GYS2 | 0.766327 | 3 | 0 | 3 |
| MOV10L1 | TMOD3 | 0.758857 | 3 | 0 | 3 |
| MOV10L1 | CSTB | 0.756219 | 3 | 0 | 3 |
| MOV10L1 | PPL | 0.754835 | 3 | 0 | 3 |
| MOV10L1 | NAPA | 0.754766 | 3 | 0 | 3 |
| MOV10L1 | PKP3 | 0.752778 | 3 | 0 | 3 |
| MOV10L1 | RANBP9 | 0.751456 | 3 | 0 | 3 |
| MOV10L1 | S100A14 | 0.748584 | 3 | 0 | 3 |
| MOV10L1 | ACOX3 | 0.748012 | 3 | 0 | 3 |
| MOV10L1 | RMND5B | 0.747236 | 3 | 0 | 3 |
| MOV10L1 | AIF1L | 0.74704 | 3 | 0 | 3 |
| MOV10L1 | FBXL16 | 0.746143 | 3 | 0 | 3 |
| MOV10L1 | RNF208 | 0.74441 | 3 | 0 | 3 |
For details and further investigation, click here
