| Full name: GID complex subunit 8 homolog | Alias Symbol: FLJ20602|bA305P22.1|TWA1 | ||
| Type: protein-coding gene | Cytoband: 20q13.33 | ||
| Entrez ID: 54994 | HGNC ID: HGNC:15857 | Ensembl Gene: ENSG00000101193 | OMIM ID: 611625 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of GID8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GID8 | 54994 | 218448_at | 0.2680 | 0.7452 | |
| GSE20347 | GID8 | 54994 | 218448_at | -0.8899 | 0.0000 | |
| GSE23400 | GID8 | 54994 | 218448_at | -0.3740 | 0.0002 | |
| GSE26886 | GID8 | 54994 | 225376_at | -0.9819 | 0.0005 | |
| GSE29001 | GID8 | 54994 | 218448_at | -0.5984 | 0.0449 | |
| GSE38129 | GID8 | 54994 | 218448_at | -0.3532 | 0.0714 | |
| GSE45670 | GID8 | 54994 | 218448_at | -0.2777 | 0.1501 | |
| GSE53622 | GID8 | 54994 | 72930 | -0.2581 | 0.0158 | |
| GSE53624 | GID8 | 54994 | 72930 | -0.3437 | 0.0000 | |
| GSE63941 | GID8 | 54994 | 225376_at | -0.0001 | 0.9999 | |
| GSE77861 | GID8 | 54994 | 218448_at | -0.7198 | 0.0085 | |
| SRP007169 | GID8 | 54994 | RNAseq | -2.1450 | 0.0000 | |
| SRP008496 | GID8 | 54994 | RNAseq | -2.0205 | 0.0000 | |
| SRP064894 | GID8 | 54994 | RNAseq | -0.6692 | 0.0003 | |
| SRP133303 | GID8 | 54994 | RNAseq | -0.5877 | 0.0000 | |
| SRP159526 | GID8 | 54994 | RNAseq | -0.5718 | 0.0045 | |
| SRP193095 | GID8 | 54994 | RNAseq | -0.9628 | 0.0000 | |
| SRP219564 | GID8 | 54994 | RNAseq | -0.5592 | 0.1824 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by GID8 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of GID8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GID8 | 54994 | 14 | 2 | 14 | |
| GSE20123 | GID8 | 54994 | 14 | 2 | 14 | |
| GSE43470 | GID8 | 54994 | 11 | 1 | 31 | |
| GSE46452 | GID8 | 54994 | 35 | 0 | 24 | |
| GSE47630 | GID8 | 54994 | 25 | 1 | 14 | |
| GSE54993 | GID8 | 54994 | 0 | 16 | 54 | |
| GSE54994 | GID8 | 54994 | 29 | 0 | 24 | |
| GSE60625 | GID8 | 54994 | 0 | 0 | 11 | |
| GSE74703 | GID8 | 54994 | 10 | 0 | 26 | |
| GSE74704 | GID8 | 54994 | 11 | 0 | 9 | |
| TCGA | GID8 | 54994 | 44 | 4 | 48 |
Total number of gains: 193; Total number of losses: 26; Total Number of normals: 269.
Somatic mutations of GID8:
Generating mutation plots.
Highly correlated genes for GID8:
Showing top 20/1118 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GID8 | DNAJC5 | 0.774974 | 5 | 0 | 5 |
| GID8 | SH3BGRL2 | 0.747081 | 3 | 0 | 3 |
| GID8 | HDHD2 | 0.746344 | 3 | 0 | 3 |
| GID8 | ANKRD13A | 0.740357 | 3 | 0 | 3 |
| GID8 | ZNRF1 | 0.733755 | 4 | 0 | 4 |
| GID8 | CAPNS2 | 0.726342 | 3 | 0 | 3 |
| GID8 | CPEB4 | 0.720224 | 3 | 0 | 3 |
| GID8 | PDCD6IP | 0.71823 | 8 | 0 | 8 |
| GID8 | SPNS2 | 0.718008 | 3 | 0 | 3 |
| GID8 | TBC1D20 | 0.718007 | 3 | 0 | 3 |
| GID8 | ABHD5 | 0.712458 | 6 | 0 | 6 |
| GID8 | TOM1 | 0.711677 | 8 | 0 | 7 |
| GID8 | ITCH | 0.709885 | 10 | 0 | 8 |
| GID8 | MPP7 | 0.708538 | 3 | 0 | 3 |
| GID8 | RASSF5 | 0.70521 | 4 | 0 | 4 |
| GID8 | MKRN2 | 0.704236 | 4 | 0 | 4 |
| GID8 | MUC20 | 0.702795 | 3 | 0 | 3 |
| GID8 | VSIG10L | 0.701006 | 4 | 0 | 3 |
| GID8 | NRBP1 | 0.700359 | 6 | 0 | 6 |
| GID8 | SULT2B1 | 0.699818 | 7 | 0 | 6 |
For details and further investigation, click here
