| Full name: glyoxalase I | Alias Symbol: GLOD1 | ||
| Type: protein-coding gene | Cytoband: 6p21.2 | ||
| Entrez ID: 2739 | HGNC ID: HGNC:4323 | Ensembl Gene: ENSG00000124767 | OMIM ID: 138750 |
| Drug and gene relationship at DGIdb | |||
Expression of GLO1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GLO1 | 2739 | 200681_at | 0.4047 | 0.1850 | |
| GSE20347 | GLO1 | 2739 | 200681_at | 0.0872 | 0.6258 | |
| GSE23400 | GLO1 | 2739 | 200681_at | 0.3844 | 0.0000 | |
| GSE26886 | GLO1 | 2739 | 200681_at | 0.5047 | 0.0007 | |
| GSE29001 | GLO1 | 2739 | 200681_at | 0.2355 | 0.4469 | |
| GSE38129 | GLO1 | 2739 | 200681_at | 0.3009 | 0.0122 | |
| GSE45670 | GLO1 | 2739 | 200681_at | 0.2875 | 0.0394 | |
| GSE53622 | GLO1 | 2739 | 118944 | 0.3529 | 0.0000 | |
| GSE53624 | GLO1 | 2739 | 118944 | 0.4177 | 0.0000 | |
| GSE63941 | GLO1 | 2739 | 200681_at | 0.8319 | 0.0140 | |
| GSE77861 | GLO1 | 2739 | 200681_at | 0.1530 | 0.3792 | |
| GSE97050 | GLO1 | 2739 | A_23_P214411 | 0.3899 | 0.3038 | |
| SRP007169 | GLO1 | 2739 | RNAseq | -0.2717 | 0.4589 | |
| SRP008496 | GLO1 | 2739 | RNAseq | -0.2597 | 0.1693 | |
| SRP064894 | GLO1 | 2739 | RNAseq | 0.4101 | 0.0660 | |
| SRP133303 | GLO1 | 2739 | RNAseq | 0.8665 | 0.0001 | |
| SRP159526 | GLO1 | 2739 | RNAseq | 0.3419 | 0.0686 | |
| SRP193095 | GLO1 | 2739 | RNAseq | -0.0703 | 0.6488 | |
| SRP219564 | GLO1 | 2739 | RNAseq | -0.3547 | 0.1835 | |
| TCGA | GLO1 | 2739 | RNAseq | 0.1400 | 0.0018 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GLO1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GLO1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GLO1 | 2739 | 4 | 2 | 24 | |
| GSE20123 | GLO1 | 2739 | 4 | 2 | 24 | |
| GSE43470 | GLO1 | 2739 | 6 | 0 | 37 | |
| GSE46452 | GLO1 | 2739 | 2 | 9 | 48 | |
| GSE47630 | GLO1 | 2739 | 8 | 4 | 28 | |
| GSE54993 | GLO1 | 2739 | 3 | 2 | 65 | |
| GSE54994 | GLO1 | 2739 | 11 | 4 | 38 | |
| GSE60625 | GLO1 | 2739 | 0 | 1 | 10 | |
| GSE74703 | GLO1 | 2739 | 6 | 0 | 30 | |
| GSE74704 | GLO1 | 2739 | 1 | 2 | 17 | |
| TCGA | GLO1 | 2739 | 18 | 14 | 64 |
Total number of gains: 63; Total number of losses: 40; Total Number of normals: 385.
Somatic mutations of GLO1:
Generating mutation plots.
Highly correlated genes for GLO1:
Showing top 20/1179 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GLO1 | CNOT10 | 0.79569 | 3 | 0 | 3 |
| GLO1 | NLK | 0.789963 | 3 | 0 | 3 |
| GLO1 | REST | 0.771794 | 3 | 0 | 3 |
| GLO1 | CCDC14 | 0.761862 | 3 | 0 | 3 |
| GLO1 | ERCC6 | 0.758926 | 3 | 0 | 3 |
| GLO1 | LRRC58 | 0.75736 | 4 | 0 | 4 |
| GLO1 | CENPBD1 | 0.751824 | 3 | 0 | 3 |
| GLO1 | SSBP4 | 0.750037 | 3 | 0 | 3 |
| GLO1 | RPP38 | 0.746793 | 4 | 0 | 4 |
| GLO1 | GPR160 | 0.739918 | 3 | 0 | 3 |
| GLO1 | ERP27 | 0.729809 | 3 | 0 | 3 |
| GLO1 | RRP36 | 0.728046 | 7 | 0 | 7 |
| GLO1 | TCF12 | 0.724782 | 4 | 0 | 4 |
| GLO1 | NSUN3 | 0.723975 | 3 | 0 | 3 |
| GLO1 | SESN3 | 0.721936 | 3 | 0 | 3 |
| GLO1 | PPIL1 | 0.721367 | 9 | 0 | 9 |
| GLO1 | ATG4C | 0.711442 | 3 | 0 | 3 |
| GLO1 | HAUS1 | 0.709441 | 4 | 0 | 4 |
| GLO1 | SFXN2 | 0.707357 | 3 | 0 | 3 |
| GLO1 | WDR5 | 0.700039 | 4 | 0 | 3 |
For details and further investigation, click here
