| Full name: transmembrane protein 223 | Alias Symbol: MGC3196 | ||
| Type: protein-coding gene | Cytoband: 11q12.3 | ||
| Entrez ID: 79064 | HGNC ID: HGNC:28464 | Ensembl Gene: | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM223:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM223 | 79064 | 220934_s_at | 0.4217 | 0.1820 | |
| GSE20347 | TMEM223 | 79064 | 220934_s_at | 0.6078 | 0.0003 | |
| GSE23400 | TMEM223 | 79064 | 220934_s_at | 0.3464 | 0.0000 | |
| GSE26886 | TMEM223 | 79064 | 220934_s_at | 1.3518 | 0.0000 | |
| GSE29001 | TMEM223 | 79064 | 220934_s_at | 0.4742 | 0.2400 | |
| GSE38129 | TMEM223 | 79064 | 220934_s_at | 0.5761 | 0.0001 | |
| GSE45670 | TMEM223 | 79064 | 220934_s_at | 0.5243 | 0.0049 | |
| GSE63941 | TMEM223 | 79064 | 220934_s_at | -0.7004 | 0.1756 | |
| GSE77861 | TMEM223 | 79064 | 220934_s_at | 0.6109 | 0.0062 | |
| GSE97050 | TMEM223 | 79064 | A_23_P1956 | 0.4955 | 0.1497 | |
| SRP007169 | TMEM223 | 79064 | RNAseq | 0.7963 | 0.0437 | |
| SRP008496 | TMEM223 | 79064 | RNAseq | 0.6173 | 0.0323 | |
| SRP064894 | TMEM223 | 79064 | RNAseq | 0.6079 | 0.0351 | |
| SRP133303 | TMEM223 | 79064 | RNAseq | 0.4160 | 0.0281 | |
| SRP159526 | TMEM223 | 79064 | RNAseq | 0.6250 | 0.0118 | |
| SRP193095 | TMEM223 | 79064 | RNAseq | 0.2919 | 0.0139 | |
| SRP219564 | TMEM223 | 79064 | RNAseq | 0.6566 | 0.0774 | |
| TCGA | TMEM223 | 79064 | RNAseq | 0.2413 | 0.0011 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TMEM223 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of TMEM223:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM223 | 79064 | 6 | 5 | 19 | |
| GSE20123 | TMEM223 | 79064 | 6 | 5 | 19 | |
| GSE43470 | TMEM223 | 79064 | 1 | 6 | 36 | |
| GSE46452 | TMEM223 | 79064 | 8 | 4 | 47 | |
| GSE47630 | TMEM223 | 79064 | 3 | 7 | 30 | |
| GSE54993 | TMEM223 | 79064 | 3 | 0 | 67 | |
| GSE54994 | TMEM223 | 79064 | 5 | 5 | 43 | |
| GSE60625 | TMEM223 | 79064 | 0 | 3 | 8 | |
| GSE74703 | TMEM223 | 79064 | 1 | 3 | 32 | |
| GSE74704 | TMEM223 | 79064 | 4 | 3 | 13 | |
| TCGA | TMEM223 | 79064 | 12 | 11 | 73 |
Total number of gains: 49; Total number of losses: 52; Total Number of normals: 387.
Somatic mutations of TMEM223:
Generating mutation plots.
Highly correlated genes for TMEM223:
Showing top 20/1525 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM223 | EME1 | 0.797845 | 5 | 0 | 5 |
| TMEM223 | BMP2 | 0.786832 | 3 | 0 | 3 |
| TMEM223 | C1orf131 | 0.769668 | 5 | 0 | 5 |
| TMEM223 | CPSF3 | 0.759776 | 5 | 0 | 5 |
| TMEM223 | PSMG3 | 0.757413 | 5 | 0 | 5 |
| TMEM223 | UBE2T | 0.756655 | 5 | 0 | 5 |
| TMEM223 | CDCA2 | 0.754098 | 5 | 0 | 5 |
| TMEM223 | LRRCC1 | 0.746507 | 3 | 0 | 3 |
| TMEM223 | MED19 | 0.743894 | 4 | 0 | 4 |
| TMEM223 | NUF2 | 0.741972 | 5 | 0 | 5 |
| TMEM223 | TRMT6 | 0.739709 | 5 | 0 | 5 |
| TMEM223 | IPO4 | 0.734469 | 5 | 0 | 4 |
| TMEM223 | UBTD2 | 0.733852 | 3 | 0 | 3 |
| TMEM223 | KNSTRN | 0.733106 | 4 | 0 | 4 |
| TMEM223 | SSRP1 | 0.732227 | 9 | 0 | 9 |
| TMEM223 | TBX1 | 0.73119 | 4 | 0 | 4 |
| TMEM223 | MTFR2 | 0.729774 | 4 | 0 | 4 |
| TMEM223 | SIX4 | 0.729156 | 5 | 0 | 5 |
| TMEM223 | GAS2L1 | 0.728896 | 5 | 0 | 5 |
| TMEM223 | GPR158 | 0.728801 | 3 | 0 | 3 |
For details and further investigation, click here
